|drug3847||laparoscopic or open appendicectomy Wiki||0.50|
|drug475||Blood sample for serological test Wiki||0.50|
There are 4 clinical trials
The study aims to examine whether a nationwide lock-down with an entire population subjugated to social distancing reduces the incidence of appendicitis. If a reduction is detected it supports the hypothesis that infectious disease may play a role in the etiology of appendicitis.
Description: Appendectomy or other surgery for appendicitisMeasure: Appendectomy Time: 5 weeks
Description: Postoperative length of stayMeasure: Postoperative length of stay Time: 30 days
Description: Overall mortalityMeasure: Mortality Time: 30 days
Description: Perforated appendicitis or periappendicular abscessMeasure: Incidence of complicated appendicitis Time: 5 weeks
Appendicitis is one of the most common clinical conditions in general surgery. The diagnosis is usually made from clinical examination, imaging (sonography or CT) and laboratory parameters. The laparoscopic appendectomy without drainage has established as the gold standard. Patients usually leave the hospital two days after surgery. In times of corona crisis, patients are unsure to visit the hospital because of fear of infection with SARS-CoV-2. A higher incidence of perforated appendicitis could be an indicator for fear-related delay of going to the hospital. Methods: Investigators performed a retrospective analysis on the incidence of perforated appendicitis in a 10-week interval (mid-March to end of May) of the years 2018, 2019 and 2020 to evaluate possible changes in times of corona crisis. Intraoperative findings, procedures, complications and the length of hospital stay were considered.
During the Covid-19 pandemic, non-operative management for acute appendicitis (AA) was implemented in the UK. The aim of this study was to determine the efficacy and outcomes of conservative versus surgical management of AA during the pandemic.
Description: Death secondary to acute appendicitisMeasure: Mortality Time: within 90 days of a patient's initial presentation
Description: failure of conservative management and need to undergo surgeryMeasure: Failure of primary proposed treatment Time: within 90 days of a patient's initial presentation
Description: length of stay in hospital from admission date till discharge date or deathMeasure: length of stay Time: within 90 days of a patient's initial presentation
Description: Re-attendance to hospital after patient's discharge whether planned or unplannedMeasure: Re-attendance Time: within 90 days of a patient's initial presentation
Description: imaging modality obtained and findings to confirm the diagnosis of acute appendicitisMeasure: Imaging Time: within 90 days of a patient's initial presentation
Description: Intra-operative findings of pus or free fluid during appendicectomyMeasure: Intra-operative findings during surgery Time: within 90 days of a patient's initial presentation
retrospective observational study of variation in incidence and clinical presentation of appendicitis during the pandemic in northern Italy, compared with the same period in the previous 2 years.
Description: Number of patients with complicated acute appendicitisMeasure: complicated appendicitis Time: 2 months
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.Drug Reports MeSH Reports HPO Reports