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D000073397: Occupational Stress

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO

Correlated Drug Terms (13)

Name (Synonyms) Correlation
drug3198 Sudarshan Kriya Yoga (SKY) Wiki 0.45
drug3864 maslach burnout inventory questionnair Wiki 0.45
drug1392 Health Enhancement Program Wiki 0.45
Name (Synonyms) Correlation
drug2788 Remote Automated Monitoring System Wiki 0.45
drug4075 vitamin D Wiki 0.45
drug2643 Psychological stress and adaptation at work score (PSAS) Wiki 0.45
drug2953 Saliva sample collection Wiki 0.32
drug295 Assessment of work-related stress Wiki 0.32
drug289 Assessment of behavioral response to emotional stimulation Wiki 0.32
drug691 Cardiac and electrodermal recordings Wiki 0.32
drug621 COVID-19 patients Wiki 0.32
drug1262 Favipiravir Wiki 0.09
drug2448 Placebo Wiki 0.04

Correlated MeSH Terms (6)

Name (Synonyms) Correlation
D000068376 Compassion Fatigue NIH 0.32
D000067073 Psychological Trauma NIH 0.32
D002055 Burnout, Professional NIH 0.15
Name (Synonyms) Correlation
D013315 Stress, Psychological NIH 0.08
D018352 Coronavirus Infections NIH 0.03
D045169 Severe Acute Respiratory Syndrome NIH 0.02

Correlated HPO Terms (0)

Name (Synonyms) Correlation

Clinical Trials

Navigate: Correlations   HPO

There are 5 clinical trials

1 Psychological Impact of COVID19 Among Doctors in Assiut University Hospitals

study aimed to investigate the psychological impact of corona virus among doctor in Assiut University Hospitals, mainly stress and burn out will be assessed

  1. Occupational Stress
  1. Other: maslach burnout inventory questionnair
MeSH:Occupational Stress

Primary Outcomes

Description: Emotional Exhaustion measures feelings of being emotionally overextended and exhausted by one's work. Depersonalization measures an unfeeling and impersonal response toward patients. Personal Accomplishment measures feelings of competence and successful achievement in one's work. All MBI items are scored using a 7 level frequency scale from "never" to "daily." Initial development had 3 components: emotional exhaustion (9 items), depersonalization (5 items) and personal achievement (8 items). Each scale measures its own unique dimension of burnout

Measure: The MBI-HSS (MP) addresses three scales:Emotional Exhaustion ,Depersonalization and Personal Accomplishment

Time: baseline

Secondary Outcomes

Description: The scale asks whether the respondent has experienced a particular symptom or behavior recently. Each item is rated on a four-point scale (less than usual, no more than usual, rather more than usual, or much more than usual); and for example when using the GHQ-12 it gives a total score of 36 or 12 based on the selected scoring methods. it measure social dysfunction, anxiety and depression and loss of confidence

Measure: GHQ-12 questionnaire for measuring of current mental health

Time: baseline
2 Stress Biomarkers Leading to Professional Burnout Among People Involved in a Mobile Intensive Care Unit During the COVID-19 Pandemic

This study is aiming at investigating whether professional burnout in people involved in the mobile intensive care unit (in French: Element Mobile de RĂ©animation, EMR) in Mulhouse (France) can be predicted upstream by a low mindfulness level (as a protective factor) or by a dysregulation of stress pathways with a high level of perceived stress towards an emotional event (psychological index of allostatic load), i.e. an early and silent dysfunctional physiological response (measured by the electrophysiological and biological measurements of allostasis load and parasympathetic brake). It is part of a global approach aiming at identifying levers to prevent the allostatic load of occupational stress related to large-scale health crises.

  1. Occupational Stress
  1. Behavioral: Assessment of work-related stress
  2. Biological: Saliva sample collection
  3. Other: Cardiac and electrodermal recordings
  4. Behavioral: Assessment of behavioral response to emotional stimulation
MeSH:Occupational Stress Burnout, Professional

Primary Outcomes

Description: Professional burnout is measured at D21 by the Burnout Measure Short Version (BMS) questionnaire It is a 10-item questionnaire used to assess burnout regardless of the occupational category. Each item is rated from 0 to 6 ("never" to "always"). An average score (sum/10) below 2.4 indicates a very low degree of burnout exposure; a score between 2.5 and 3.4 indicates a low degree of burnout exposure; a score between 3.5 and 4.4 indicates the presence of burnout; a score between 4.5 and 5.4 indicates a high degree of burnout exposure; a score above 5.5 indicates a very high degree of burnout exposure.

Measure: Professional burnout

Time: 21 days after enrollment (Day 21)

Description: Mindfulness level is assessed at D0 thanks to the Freiburg Mindfulness Inventory. It is a 14 item scale. Each item is rated from 1 to 4 ("almost never" to "almost always"). The total score is between 14 and 56. The mean value in a population of young adults under 36 years of age is 38.5 (+/- 5.1 standard deviation).

Measure: Mindfulness level

Time: Day 1

Secondary Outcomes

Description: Perceived stress level is assessed with the Perceived Stress Scale (PSS). It is a 14 item scale. Each item is rated from 0 to 5 ("never" to "very often"). The total score ranges from 0 to 56 with higher scores indicating greater perceived stress.

Measure: Perceived stress level following the emotional stimulation

Time: Day 1

Description: Parasympathetic flexibility is assessed through dynamic electro-physiological analysis of cardiac and electrodermal conductance recordings. Physiological and cognitive reserve of emotional regulation is assessed through the analysis of the spectral power of the 0.1 Hz frequency band at emotional recall.

Measure: Parasympathetic flexibility evolution during emotional recall

Time: Day 1

Description: The activity of the sympathetic tone is assessed by the measurement of the resting state salivary Chromogranin A. Physiological and cognitive reserve of emotional regulation is assessed through the analysis of the spectral power of the 0.1 Hz frequency band at emotional recall. The activity of the sympathetic tone is assessed by the measurement of the resting salivary Chromogranin A.

Measure: Sympathetic tone at rest

Time: Day 1

Description: Corticotropic activation at rest is assessed through the DHEA/cortisol level ratio

Measure: Corticotropic activation at rest

Time: Day 1

Description: The Hospital Anxiety and Depression Scale (HAD-s32) is used to assess mood disorders in the general non-psychiatric population. It is used to discriminate between anxiety and depression. Scores greater than 11 are indicative of charcaterized anxiety/depression.

Measure: Mood disorders (anxiety / depression)

Time: Day 1

Description: Post-traumatic disorder is assessed with the PCL-5. It is a 20-item self-administered questionnaire representing DSM-5 PTSD diagnosis symptoms rated by the subject on a scale from 0 ("not at all") to 4 ("extremely") during the past month. Scores range from 0 to 80. A score greater than of 33 evokes the presence of post-traumatic stress disorder.

Measure: Post-traumatic stress disorder

Time: Day 1

Description: Sleep quality is assesses thanks to the Leeds Sleep Evaluation questionnaire (LEEDS). It consists of ten visual analogue scales assessing four aspects of sleep: (i) quality of falling asleep and degree of drowsiness, (ii) quality of sleep, (iii) quality of wakefulness, and (iv) quality of post-wakefulness and performance.

Measure: Sleep quality

Time: Day 1
3 Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness (BREATH): an RCT for Frontline Hospital and Long-term Care Home Staff Managing the COVID-19 Pandemic

This study will examine the feasibility of conducting an online Randomized Controlled Trial (RCT) in frontline hospital and long term care healthcare staff in managing COVID-19 patients in London, ON. The study will randomize participants to Sudarshan Kriya Yoga (SKY) or a Health Enhancement Program (HEP).

  1. Job Stress
  2. Workplace Stress
  3. Compassion Fatigue
  4. Psychological Trauma
  5. Healthcare Workers
  6. Healthcare Providers
  1. Other: Sudarshan Kriya Yoga (SKY)
  2. Other: Health Enhancement Program
MeSH:Compassion Fatigue Occupational Stress Psychological Trauma

Primary Outcomes

Description: The number of participants recruited per month will be calculated as a feasibility measure.

Measure: Rate of participant recruitment

Time: 1 year

Description: The retention rate of participants will be calculated as a feasibility measure.

Measure: Rate of retention

Time: 1 year

Description: The completeness of study assessments will be assessed as a feasibility measure by calculating the missing percentage of data in case report forms.

Measure: Completeness of data entry

Time: 1 year

Description: The cost of both study interventions will be calculated to assess the total study cost for interventions and the cost per participant. This information will be used as a feasibility measure.

Measure: Cost of interventions

Time: 1 year

Description: The total of unexpected costs will be calculated as a feasibility measure.

Measure: Unexpected costs

Time: 1 year

Secondary Outcomes

Description: The Athens Insomnia Scale will be used to assess insomnia. This scale is an 8-item, self-rated measure of the extent of sleep difficulties over the last 30 days with each item representing a different aspect of sleep (e.g. "Overall Quality of Sleep"). Ratings are from 0 to 4, with 0 being no difficulty with the item and 4 being the most difficulty with the item. Higher overall scores on this scale indicate higher difficulties with sleep.

Measure: Change in Athens Insomnia Scale

Time: Change from Week 0 to week 3 and to week 5

Description: The Generalized Anxiety Disorder 7-item scale (each scored 0-3) is a self-rated measure of anxiety and has been validated for the diagnosis of Generalized Anxiety Disorder in the adult population. Scores range from 0 to 21. Higher scores indicate greater anxiety symptoms (5-9, mild anxiety; 10-14, moderate anxiety; 15-21 severe anxiety).

Measure: Change in Generalized Anxiety Disorder 7-item scale

Time: Change from Week 0 to week 3 and to week 5

Description: The Patient Health Questionnaire (PHQ-9) is a 9-item, self-rated measure of depression which has been validated for screening a major depressive episode in adults. Total scores indicate various levels of depression: 0-4, no depression; 5-9, mild depression; 10-14, moderate depression; 15-19, moderately severe depression; 20-27, severe depression.

Measure: Change in Patient Health Questionnaire 9

Time: Change from Week 0 to week 3 and to week 5

Description: The Connor-Davidson Resilience Scale (CD-RISC) is a brief self-rated assessment tool that comprises of 10 items, each rated on a 5-point Likert scale (0 = not true at all to 4 = true nearly all the time). Higher scores reflect greater resilience, which is a measure of one's ability to cope with stress. The scale demonstrated strong reliability and validity and has been studied in a variety of populations including medical personnel, nurses, social workers and physicians).

Measure: Change in Connor-Davidson Resilience Scale

Time: Change from Week 0 to week 3 and to week 5
4 Psychological Impact of COVID-19 Pandemic in Healthcare Workers in Spain: A Cross-sectional Study. PSIMCOV Group

Background. The current coronavirus disease (COVID-19) has a great impact worldwide. Healthcare workers play an essential role and are one of the most exposed groups.Information about the psychosocial impact on healthcare workers is limited. Methods. 3109 healthcare workers completed a national, internet-based, cross-sectional 45-item survey between 9 and 19 April 2020. The objective is to assess the psychological impact of the COVID-19 pandemic in Spanish healthcare workers. A Psychological Stress and Adaptation at work Score (PSAS) was defined combining four modified versions of validated psychological assessment tests (A) Healthcare Stressful Test, (B) Coping Strategies Inventory,(C) Font-Roja Questionnaire and (D) Trait Meta-Mood Scale.

  1. Covid19
  2. Stress, Psychological
  3. Work Related Stress
  4. Epidemic Disease
  5. SARS-CoV Infe
  6. SARS-CoV Infection
  1. Diagnostic Test: Psychological stress and adaptation at work score (PSAS)
MeSH:Coronavirus Infections Severe Acute Respiratory Syndrome Occupational Stress Stress, Psychological

Primary Outcomes

Description: evaluate the severity of psychological impact of the pandemic in Spain in healthcare workers

Measure: PSAS (Psychological Stress and Adaptation at work Score) during the crisis

Time: during the pandemic (April 9, 2020 to April 19, 2020)

Secondary Outcomes

Description: evaluate the psychological stress in Spain in healthcare workers

Measure: PSAS (Psychological Stress and Adaptation at work Score) in basal conditions

Time: After the pandemic (back to regular activity to be considered in the future as we do not know it yet. It expected to be in less than one year.
5 Perceived Stress and Needs Among Medical Staff in ICU During COVID-19 Crisis

The objective of this study is to compare psychological distress and needs of nurses in ICU before and during coronavirus pandemic.

  1. Coronavirus
  2. Nurse's Role
  3. Professional Stress
MeSH:Coronavirus Infections Occupational Stress

Primary Outcomes

Description: Job Content Questionnaire (Karasek, 1979)

Measure: stress at work

Time: change from baseline at one year

Description: Nursing Stress Questionnaire (Gray-Toft, 1981)

Measure: stress in a medical unit

Time: change from baseline at one year

Secondary Outcomes

Description: We will ask if they are used to do activities like hypnosis, yoga, mediation, sport, etc. This factor could help us to know if these activities can help and if we have to promote them in the hospital.

Measure: hobby activities

Time: change from baseline at one year

HPO Nodes


Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials

HPO Nodes


Data processed on December 13, 2020.

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