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D006948: Hyperkinesis

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug1672 Interview by psychologists Wiki 1.00
drug544 CD24Fc Wiki 1.00
drug2448 Placebo Wiki 0.05

Correlated MeSH Terms (5)


Name (Synonyms) Correlation
D002659 Child Development Disorders, Pervasive NIH 0.71
D001289 Attention Deficit Disorder with Hyperactivity NIH 0.58
D001321 Autistic Disorder NIH 0.58
Name (Synonyms) Correlation
D000067877 Autism Spectrum Disorder NIH 0.50
D004194 Disease NIH 0.20

Correlated HPO Terms (4)


Name (Synonyms) Correlation
HP:0002487 Hyperkinetic movements HPO 1.00
HP:0000717 Autism HPO 0.71
HP:0007018 Attention deficit hyperactivity disorder HPO 0.58
Name (Synonyms) Correlation
HP:0000729 Autistic behavior HPO 0.58

Clinical Trials

Navigate: Correlations   HPO

There is one clinical trial.


1 Clinical Evolution and Parenting in Children and Adolescents With Autism Spectrum Disorder or Attention Deficit Hyperactivity Disorder Quarantined Because of Covid-19 Outbreak

In response to the coronavirus disease 2019 (covid-19) outbreak, the home confinement of the population ordered by governments in many countries raise questions about its impact on individuals' physical and mental health in the short and longer term. In children, reduced physical activity, changes in lifestyle, disturbances in sleep patterns, lack of in-person contact with peers, poor or inadequate understanding of health risks may be risk factors of anxiety, stress, fatigue, sleep disorders (Brooks et al, 2020; Wang et al, 2020; Sprang et al, 2013). These problematic effects could be modulated by social factors (housing in urban or rural areas, availability of personal space at home, parenting stress, etc.) (Cluver et al, 2020; Liu et al, 2020).

NCT04416360
Conditions
  1. Autism Spectrum Disorder
  2. Attention-deficit Hyperactivity Disorder
Interventions
  1. Other: Interview by psychologists
MeSH:Hyperkinesis Disease Autistic Disorder Attention Deficit Disorder with Hyperactivity Autism Spectrum Disorder Child Development Disorders, Pervasive
HPO:Attention deficit hyperactivity disorder Autism Autistic behavior Hyperactivity Hyperkinetic movements

Primary Outcomes

Description: composition, home confinement, change in the environment, personal room at home, screens with internet access, parents' current professional status, teleworking, care, family concerns related to Covid-19, parenting stress, schooling, recurrent complaints.

Measure: Interview of the parents : contextual data

Time: Baseline

Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)

Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general

Time: Baseline

Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)

Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general

Time: 1 month

Description: related to education; related to daily family life; related to leisure, related to care (children/adolescents, parents)

Measure: Interview of the children/adolescents/ parents : Experience of the confinement in general

Time: 3 months

Description: Data relating to disease and management of care. Experience of the referring caregiver.

Measure: Interview of the referring caregiver : data relating to disease and management of care

Time: 3 months

HPO Nodes


HP:0000752: Hyperactivity
Genes 603
EZR TGIF1 MBD5 SH2B1 EEF1A2 KCNA1 GNE TBL1X ALG13 HSPG2 NODAL GNE CUL4B POLA1 DHCR7 NSUN2 AGTR2 AMT ZNF711 GTF2IRD1 SLC9A7 NECAP1 PIGY RAB39B PHF21A FRMPD4 CNKSR2 SATB2 KIF11 SHH ARX NTRK1 GABRG2 ST3GAL3 ARVCF SLITRK1 SETD5 MED13 YY1 RREB1 GNB5 GCSH TRAPPC14 DNM1 STXBP1 FBXO11 STEEP1 ARX HUWE1 AIMP1 ATP10A UBE3A AARS1 PIEZO2 FGF8 DMD RAB39B GAS1 EBP TGFBR2 FOXH1 CLIP2 ELN GRIN2A FANCD2 MYT1L HIRA CC2D1A GP1BB SVBP ACTL6B ADNP DLL1 SEC24C SIX3 CDK8 TIMM8A GABRG2 ELN PIK3CA HCN1 PAH MBOAT7 CLTC SATB2 TLK2 WAC GNS PMS2 FOXH1 CLCN4 GABRA5 TTI2 AFF2 GABRG2 CDON TSC1 GDI1 SLC1A2 PTCHD1 GAS1 PDE4D SHOC2 HDC GABRB2 CREBBP NPAP1 KMT2A PTCH1 FRRS1L OPHN1 CC2D1A KRAS JRK SCN1A NTRK2 CDON CDK19 KMT2E IGF2 SHH DISP1 ASPM TANC2 STS ZIC2 NFIX ACTL6B SNORD115-1 LIG4 GALC MADD NF1 DISP1 MAN1B1 FGD1 ARG1 KCNB1 PAK3 MKRN3-AS1 FOXH1 TSPAN7 YWHAG SEMA3E TDGF1 IKBKG KDM5B DHTKD1 FAN1 TKT VPS13A FTSJ1 MED13 NBN GLI2 FGF8 ABCD1 ANK3 YWHAG PPM1D CNKSR2 DPYD GRIA4 PNKP FGFR1 IGF1 ZNF81 SMARCC2 PUF60 CCBE1 PDE4D TAF1 KMT2A PWRN1 IPW HOXA2 PNKP CHRNA7 FLI1 PAK3 WDR62 SNRPN DISP1 DALRD3 PANK2 SPR TRIO STAG2 ARID2 KCNA2 ADSL SIX3 DNAJC21 RAI1 SH2B1 EBP KDM6B ZC3H14 DCPS MED12 HTT HNMT NKAP MSH6 BSCL2 DMXL2 KIF15 ZIC2 WDFY3 KIF14 CACNA1H HERC2 GABRA2 ACY1 MSH2 MED23 CAMTA1 DHCR7 FGF8 NTRK1 SHH SYNGAP1 CREBBP DYM RIC1 NOP56 FGFR3 NODAL AP3B2 DDX6 PTCH1 ZIC2 RAD21 NUS1 SOX5 TTI2 MED25 ADAT3 KANSL1 DLL1 LINS1 WASHC4 RERE CASK SLC6A8 FGF12 DNM1 ODC1 KAT8 TUSC3 BCORL1 MAGEL2 ACSL4 PCNT TET3 STS CLTC CDON SPRED1 NSDHL MID2 SIK1 CDKN1C STAG2 PPP1R12A SLC13A5 FBXW11 ALDH5A1 PTCH1 SLC45A1 GATAD2B PSMD12 GLI2 ANAPC1 PWAR1 SLC1A4 TRIP12 WAC SCN8A ASH1L AASS SLC2A1 THRB CNKSR2 TSC2 KANSL1 GLUD1 MAPK1 CARS1 IFNG NIPBL TCF20 USP9X MKRN3 CUX2 PANK2 FGFR1 DLL1 NSUN2 RAI1 TCF20 TECR OPHN1 TAF6 PCGF2 FLCN B3GALNT2 BCAP31 DYRK1A RPS20 MID2 FMR1 PAH CUL4B SNRPN PRODH HAL MED12 SHANK3 CSGALNACT1 ADAT3 IL1RAPL1 APC2 TNIK APC2 ODC1 CNTNAP2 CACNA1A TBX1 NSD1 JMJD1C C12ORF4 CREBBP RSRC1 TBX1 FBXO31 SHROOM4 NRXN1 PNP TSHR EPCAM MECP2 TNIK TBL2 SIM1 TBX1 WWOX GABRB3 SYNJ1 METTL5 DNAJC12 PRNP TUBB2B SATB2 NEXMIF CSNK2A1 MTOR FOXP1 CLIP1 RFC2 GLDC TMCO1 SARS1 GATA4 TRAPPC9 SNORD116-1 LIMK1 MED12 MYT1L CRBN PPP2R1A SIX3 PTCHD1 CRBN EP300 ATP6V1A GLI2 SMPD1 BSCL2 ARV1 CRKL EP300 CDKL5 PMS1 SZT2 MCTP2 BPTF SIN3A NEUROD2 SYP CDON ZMIZ1 TBX1 ZNF41 PRSS12 PIGP DDX3X SMC1A STEEP1 IQSEC2 CACNA1B CIC LNPK ATRX GABRB3 EDC3 UBE3A ACTL6A DEAF1 NSDHL MED12 PLA2G6 ZIC2 CLCN4 UBE3A PSMD12 SCN8A PCDH19 MLH1 SLC6A8 GABRA1 FOXH1 USP27X UBTF FGD1 KCNK9 TSC2 RAI1 PHIP GRIN2D MECP2 FGF8 GRIK2 SNRPN NDP NBN PRKCG NDST1 TANC2 TGIF1 ATP1A1 NLGN1 WAC POGZ UBE3A ZMIZ1 SMC1A PUS7 HDAC4 MANBA SLC25A13 TDGF1 TSC1 KRAS HMGA2 TRAPPC9 ATR PTCH1 IQSEC1 CNTNAP2 GLI2 TSHR SEMA4A GAS1 PPP3CA GAS1 TRIM8 DOCK3 ANK3 SETBP1 GABRB3 UFD1 TGIF1 SLC1A4 SH3KBP1 PLAG1 DPP6 GTF2I SCN2A STAG2 SHANK3 FMR1 ATRX HGSNAT KDM3B GNAQ CYFIP2 KCNA2 LMAN2L RUSC2 MED13L FRMPD4 KANSL1 AFF2 GRIN2A PTCH1 NR2F1 TRAK1 PIGC MAPK10 UBA5 SETD5 TDGF1 ZSWIM6 UQCC2 CHD2 RAI1 MED12L SCN1B DYRK1A PARS2 TGIF1 BMPR1A CHD7 STXBP1 ARF1 UPF3B ALKBH8 SMC1A CDH2 NDN SETD2 INPP5E UPF3B OCRL DHDDS TSHR METTL23 HCFC1 SHROOM4 SMC3 YME1L1 HIVEP2 TDGF1 ADNP ZDHHC9 IQSEC1 NAGLU DLL1 PGAP1 TRMT1 SHH DPH1 SIX3 RERE SLC25A22 TKT HDAC8 MLH3 HERC2 CORO1A SRPX2 STAG2 DLG3 DRD5 EP300 C12ORF4 MLXIPL FMN2 MAP1B IQSEC2 DDX3X GATAD2B BCR RSRC1 SETBP1 NKX2-1 SPG7 SCN3A GNAO1 LHCGR BCORL1 NODAL NTNG2 SGSH BAZ1B DLL1 TRAPPC4 GAMT MED12 COMT CRADD USP7 DRD4 FLII NTNG1 ARHGEF6 FOXP1 DYNC1I2 NODAL RPS6KA3 PRKAR1A AUTS2 RLIM TRIO DPF2 PAH ABCD1 PIGQ IL1RAPL1 IGF1 OCA2 DISP1
Protein Mutations 0
SNP 0

HPO

Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


HPO Nodes


HP:0000752: Hyperactivity
Genes 603
EZR TGIF1 MBD5 SH2B1 EEF1A2 KCNA1 GNE TBL1X ALG13 HSPG2 NODAL GNE CUL4B POLA1 DHCR7 NSUN2 AGTR2 AMT ZNF711 GTF2IRD1 SLC9A7 NECAP1 PIGY RAB39B PHF21A FRMPD4 CNKSR2 SATB2 KIF11 SHH ARX NTRK1 GABRG2 ST3GAL3 ARVCF SLITRK1 SETD5 MED13 YY1 RREB1 GNB5 GCSH TRAPPC14 DNM1 STXBP1 FBXO11 STEEP1 ARX HUWE1 AIMP1 ATP10A UBE3A AARS1 PIEZO2 FGF8 DMD RAB39B GAS1 EBP TGFBR2 FOXH1 CLIP2 ELN GRIN2A FANCD2 MYT1L HIRA CC2D1A GP1BB SVBP ACTL6B ADNP DLL1 SEC24C SIX3 CDK8 TIMM8A GABRG2 ELN PIK3CA HCN1 PAH MBOAT7 CLTC SATB2 TLK2 WAC GNS PMS2 FOXH1 CLCN4 GABRA5 TTI2 AFF2 GABRG2 CDON TSC1 GDI1 SLC1A2 PTCHD1 GAS1 PDE4D SHOC2 HDC GABRB2 CREBBP NPAP1 KMT2A PTCH1 FRRS1L OPHN1 CC2D1A KRAS JRK SCN1A NTRK2 CDON CDK19 KMT2E IGF2 SHH DISP1 ASPM TANC2 STS ZIC2 NFIX ACTL6B SNORD115-1 LIG4 GALC MADD NF1 DISP1 MAN1B1 FGD1 ARG1 KCNB1 PAK3 MKRN3-AS1 FOXH1 TSPAN7 YWHAG SEMA3E TDGF1 IKBKG KDM5B DHTKD1 FAN1 TKT VPS13A FTSJ1 MED13 NBN GLI2 FGF8 ABCD1 ANK3 YWHAG PPM1D CNKSR2 DPYD GRIA4 PNKP FGFR1 IGF1 ZNF81 SMARCC2 PUF60 CCBE1 PDE4D TAF1 KMT2A PWRN1 IPW HOXA2 PNKP CHRNA7 FLI1 PAK3 WDR62 SNRPN DISP1 DALRD3 PANK2 SPR TRIO STAG2 ARID2 KCNA2 ADSL SIX3 DNAJC21 RAI1 SH2B1 EBP KDM6B ZC3H14 DCPS MED12 HTT HNMT NKAP MSH6 BSCL2 DMXL2 KIF15 ZIC2 WDFY3 KIF14 CACNA1H HERC2 GABRA2 ACY1 MSH2 MED23 CAMTA1 DHCR7 FGF8 NTRK1 SHH SYNGAP1 CREBBP DYM RIC1 NOP56 FGFR3 NODAL AP3B2 DDX6 PTCH1 ZIC2 RAD21 NUS1 SOX5 TTI2 MED25 ADAT3 KANSL1 DLL1 LINS1 WASHC4 RERE CASK SLC6A8 FGF12 DNM1 ODC1 KAT8 TUSC3 BCORL1 MAGEL2 ACSL4 PCNT TET3 STS CLTC CDON SPRED1 NSDHL MID2 SIK1 CDKN1C STAG2 PPP1R12A SLC13A5 FBXW11 ALDH5A1 PTCH1 SLC45A1 GATAD2B PSMD12 GLI2 ANAPC1 PWAR1 SLC1A4 TRIP12 WAC SCN8A ASH1L AASS SLC2A1 THRB CNKSR2 TSC2 KANSL1 GLUD1 MAPK1 CARS1 IFNG NIPBL TCF20 USP9X MKRN3 CUX2 PANK2 FGFR1 DLL1 NSUN2 RAI1 TCF20 TECR OPHN1 TAF6 PCGF2 FLCN B3GALNT2 BCAP31 DYRK1A RPS20 MID2 FMR1 PAH CUL4B SNRPN PRODH HAL MED12 SHANK3 CSGALNACT1 ADAT3 IL1RAPL1 APC2 TNIK APC2 ODC1 CNTNAP2 CACNA1A TBX1 NSD1 JMJD1C C12ORF4 CREBBP RSRC1 TBX1 FBXO31 SHROOM4 NRXN1 PNP TSHR EPCAM MECP2 TNIK TBL2 SIM1 TBX1 WWOX GABRB3 SYNJ1 METTL5 DNAJC12 PRNP TUBB2B SATB2 NEXMIF CSNK2A1 MTOR FOXP1 CLIP1 RFC2 GLDC TMCO1 SARS1 GATA4 TRAPPC9 SNORD116-1 LIMK1 MED12 MYT1L CRBN PPP2R1A SIX3 PTCHD1 CRBN EP300 ATP6V1A GLI2 SMPD1 BSCL2 ARV1 CRKL EP300 CDKL5 PMS1 SZT2 MCTP2 BPTF SIN3A NEUROD2 SYP CDON ZMIZ1 TBX1 ZNF41 PRSS12 PIGP DDX3X SMC1A STEEP1 IQSEC2 CACNA1B CIC LNPK ATRX GABRB3 EDC3 UBE3A ACTL6A DEAF1 NSDHL MED12 PLA2G6 ZIC2 CLCN4 UBE3A PSMD12 SCN8A PCDH19 MLH1 SLC6A8 GABRA1 FOXH1 USP27X UBTF FGD1 KCNK9 TSC2 RAI1 PHIP GRIN2D MECP2 FGF8 GRIK2 SNRPN NDP NBN PRKCG NDST1 TANC2 TGIF1 ATP1A1 NLGN1 WAC POGZ UBE3A ZMIZ1 SMC1A PUS7 HDAC4 MANBA SLC25A13 TDGF1 TSC1 KRAS HMGA2 TRAPPC9 ATR PTCH1 IQSEC1 CNTNAP2 GLI2 TSHR SEMA4A GAS1 PPP3CA GAS1 TRIM8 DOCK3 ANK3 SETBP1 GABRB3 UFD1 TGIF1 SLC1A4 SH3KBP1 PLAG1 DPP6 GTF2I SCN2A STAG2 SHANK3 FMR1 ATRX HGSNAT KDM3B GNAQ CYFIP2 KCNA2 LMAN2L RUSC2 MED13L FRMPD4 KANSL1 AFF2 GRIN2A PTCH1 NR2F1 TRAK1 PIGC MAPK10 UBA5 SETD5 TDGF1 ZSWIM6 UQCC2 CHD2 RAI1 MED12L SCN1B DYRK1A PARS2 TGIF1 BMPR1A CHD7 STXBP1 ARF1 UPF3B ALKBH8 SMC1A CDH2 NDN SETD2 INPP5E UPF3B OCRL DHDDS TSHR METTL23 HCFC1 SHROOM4 SMC3 YME1L1 HIVEP2 TDGF1 ADNP ZDHHC9 IQSEC1 NAGLU DLL1 PGAP1 TRMT1 SHH DPH1 SIX3 RERE SLC25A22 TKT HDAC8 MLH3 HERC2 CORO1A SRPX2 STAG2 DLG3 DRD5 EP300 C12ORF4 MLXIPL FMN2 MAP1B IQSEC2 DDX3X GATAD2B BCR RSRC1 SETBP1 NKX2-1 SPG7 SCN3A GNAO1 LHCGR BCORL1 NODAL NTNG2 SGSH BAZ1B DLL1 TRAPPC4 GAMT MED12 COMT CRADD USP7 DRD4 FLII NTNG1 ARHGEF6 FOXP1 DYNC1I2 NODAL RPS6KA3 PRKAR1A AUTS2 RLIM TRIO DPF2 PAH ABCD1 PIGQ IL1RAPL1 IGF1 OCA2 DISP1
Protein Mutations 0
SNP 0

Reports

Data processed on December 13, 2020.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

Drug Reports   MeSH Reports   HPO Reports  

Interventions

4,818 reports on interventions/drugs

MeSH

706 reports on MeSH terms

HPO

306 reports on HPO terms

All Terms

Alphabetical index of all Terms

Google Colab

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