Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
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drug3661 | WebEx Physical Activity Program Wiki | 0.58 |
drug620 | COVID-19 antigen and antibody tests, and influenza rapid test Wiki | 0.58 |
Name (Synonyms) | Correlation | |
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D001930 | Brain Injuries, NIH | 0.26 |
D014947 | Wounds and Injuries NIH | 0.21 |
Name (Synonyms) | Correlation |
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Navigate: Correlations HPO
There are 3 clinical trials
During the current COVID-19 pandemic many spinal cord injury (SCI) rehabilitation services are limited to emergency management, leaving those living in the community without access to services. Unfortunately, this can lead to negative effects including increase in emotional distress, feelings of isolation, and decreased activity engagement. Due to their limited mobility and greater likelihood of respiratory illness it is imperative to provide alternative forms of activity engagement to reduce their risk for secondary complications. Physical activity has been demonstrate to have numerous benefits for individuals with SCI ranging from enhanced health through prevention of secondary complications to improved subjective well-being. The current study proposes to provide an online physical activity program through web-based videoconferencing to person with SCI to improve overall wellbeing and activity engagement. The program will consist of six weeks of twice-weekly, 45-minute sessions in which an experienced fitness instructor (i.e., wheelchair aerobics) with lived experience and a Kinesiology graduate student will lead online sessions. The sessions will be comprised of a 10-minute warm-up phase, a 25-minute aerobic phase and a 10-minute cool-down phase that will incorporate upper-extremity flexibility exercises and guided meditation. In all cases, remote (i.e., in-home) participant monitoring of physiological signals will be conducted by the instructor to ensure safety of participants. Once the program has been completed, participants will be asked to complete self-report questionnaires related to acceptability, feasibility, and limited effectiveness. Participants will also be asked to complete a brief semi-structured interview examining barriers and facilitators of the program. Participant feedback from the interviews will be used to further develop of the program to meet the needs of the population and develop sustainable approaches for access to care in the community setting through collaborations with community partners (SCI Ontario, National SCI Alliance, Ontario Neurotrauma Foundation). Ultimately, the proposed project aims to improve overall wellbeing and access to health care service for those with SCI during the COVID-19 quarantine.
Description: Treatment Satisfaction Questionnaire
Measure: Treatment Satisfaction Time: 6 weeksDescription: Spinal Cord Injury - Quality of Life Short Form
Measure: Ability to Participate in Social Roles and Activities Time: Baseline, 6 weeks, and at 3 month follow-upDescription: Spinal Cord Injury - Quality of Life Short Form
Measure: Fatigue Time: Baseline, 6 weeks, and at 3 month follow-upDescription: Spinal Cord Injury - Quality of Life Short Form
Measure: Satisfaction with Social Roles and Activities Time: Baseline, 6 weeks, and at 3 month follow-upDescription: Spinal Cord Injury - Quality of Life Short Form
Measure: Positive Affect and Well-Being Time: Baseline, 6 weeks, and at 3 month follow-upDescription: Spinal Cord Injury - Quality of Life Short Form
Measure: Pain Interference Time: Baseline, 6 weeks, and at 3 month follow-upDescription: Spinal Cord Injury - Quality of Life Short Form
Measure: Resilience Time: Baseline, 6 weeks, and at 3 month follow-upDescription: Spinal Cord Injury - Quality of Life Short Form
Measure: Self-Esteem Time: Baseline, 6 weeks, and at 3 month follow-upDescription: Fear of COVID-19 Scale
Measure: Fear of COVID-19 Scale Time: Baseline, 6 weeks, and at 3 month follow-upPersons with spinal cord injury (PwSCI) are at a greater risk for major health conditions and poorer health outcomes than persons without spinal cord injury (SCI). They often experience a great deal of health needs both on a physiological level as well as a psychosocial level. PwSCI frequently require supports and services to be able to live independently within the community. These services and supports are sometimes difficult to access within the community when the country is operating under regular capacity, in current times with the global COVID-19 pandemic, the challenges for obtaining and accessing supports and services will become much greater. The proposed project aims to identify the specific needs during this time of crisis and to provide referrals and resources to ameliorate those needs by surveying PwSCI in the St. Louis region. The project also hopes to determine if these persons experience isolation during shelter at home orders. PwSCI, who the investigators serve or have served in the past, will be contacted via phone or e-mail once a month for six months and asked to complete a questionnaire that will allow the investigators to track the participant's needs during the COVID-19 pandemic.
Description: Instrumental Support refers to the perception that people in one's social network are available to provide material or functional aid in completing daily tasks (such as making meals or providing transportation) if needed. This self-report measure for adults (ages 18 and above) is an 8-item calibrated scale.This study will use the measure to determine if people's instrumental support changes during a pandemic.
Measure: NIH Toolbox Instrumental Support Survey - change in instrumental support Time: Baseline, 3 month and 6 monthDescription: A scale designed to measure one's subjective feelings of loneliness as well as feelings of social isolation. Participants rate each of the 3 items as hardly ever (score of "1"), some of the time (score of "2"), or often (score of "3"). The scores for each individual question can be added together to give you a possible range of scores from 3 to 9. The higher the score the more lonely the person will be. This study will use the measure to determine if people feel socially isolated during a pandemic.
Measure: UCLA (University of California - Los Angeles) 3-item Loneliness Scale - change in social isolation Time: Baseline, 3 month and 6 monthDocument and evaluate the impact of societal restrictions due to the pandemic on SCI- and ABI-related disability and functional impairments, and the resultant effects on psychological wellbeing, physical wellbeing and quality of life for those with SCI/ABI.
Description: Fear of COVID-19 Questionnaire
Measure: Change in Fear of COVID-19 Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Ability to Part. in SRA
Measure: Change in ability to participate in social roles and activities Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Depression
Measure: Change in depressive symptoms Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Pos. Affect & Well-Being
Measure: Change in positive affect and well-being Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Anxiety
Measure: Change in anxiety Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Fatigue
Measure: Change in fatigue Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Emotional & Beh. Dyscontrol
Measure: Change in emotional and behavioural dyscontrol Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Satisfaction w SRA
Measure: Change in satisfaction with social roles and activities Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Sleep Disturbance
Measure: Change in sleep disturbance Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Stigma
Measure: Change in stigma Time: baseline, 3 months, 6 monthsDescription: NeuroQol SF v1.0 - Cognitive Function
Measure: Change in cognitive function Time: baseline, 3 months, 6 monthsDescription: 23 questions about strategies to social distance
Measure: Change in social distancing strategies used Time: baseline, 3 months, 6 monthsDescription: 22 questions about social distancing
Measure: Change in thoughts and feelings about social distancing Time: baseline, 3 months, 6 monthsAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on January 01, 2021.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports