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D048909: Diabetes Complications

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug2641 PrimePro™/ PrimeMSK™ Wiki 1.00
drug567 CLIA of IgG and IgM against SARS-Cov-2 Wiki 1.00

Correlated MeSH Terms (8)


Name (Synonyms) Correlation
D009140 Musculoskeletal Diseases NIH 1.00
D019636 Neurodegenerative Diseases NIH 1.00
D012871 Skin Diseases NIH 0.71
Name (Synonyms) Correlation
D009422 Nervous System Diseases NIH 0.45
D001327 Autoimmune Diseases NIH 0.38
D008171 Lung Diseases, NIH 0.21
D004194 Disease NIH 0.20
D002318 Cardiovascular Diseases NIH 0.17

Correlated HPO Terms (0)


Name (Synonyms) Correlation

Clinical Trials

Navigate: Correlations   HPO

There is one clinical trial.


1 Evaluation of the Safety, Tolerability and Efficacy of Regenerative Therapy for the Treatment of Various Chronic and Acute Conditions

This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions. Clinically observed initial findings and an extensive body of research indicate regenerative treatments are both safe and effective for the treatment of multiple conditions.

NCT04684602
Conditions
  1. Autoimmune Diseases
  2. Cardiovascular Disorders
  3. Diabetes Complications
  4. Integumentary Disease
  5. Musculoskeletal Disorders
  6. Neurodegenerative Disorders
  7. Neurologic Disorders
  8. Pulmonary Disorders
  9. Sexual Dysfunction
  10. Urologic Disorders
  11. Viral Illness
Interventions
  1. Biological: PrimePro™/ PrimeMSK™
MeSH:Musculoskeletal Diseases Lung Diseases Nervous System Diseases Neurodegenerative Diseases Cardiovascular Diseases Skin Diseases Diabetes Complications Autoimmune Diseases Disease
HPO:Abnormal lung morphology Abnormality of the cardiovascular system Abnormality of the skin Autoimmunity Neurodegeneration

Primary Outcomes

Description: General Health Outcome Instrument used to derive a simple psychometric score for health related quality of life which provides scores on various dimensions or items describing the systems. The score is derived by adding the unweighted response order of each question, with a lower score denoting a better quality of life.

Measure: Assessment of quality of life (QOL) via 36-Item Short Form Survey (SF-36) change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

Description: Upper Extremity Outcome Instrument

Measure: Assessment of disabilities of arm, shoulder, hand via DASH Questionnaire change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

Description: Erectile Function Questionnaire. Scoring exists from 0 to 25. The lower the score, the more severe the Erectile Dysfunction.

Measure: Assessment of erectile function via International Index of Erectile Function (IIEF-5) change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

Description: COPD Outcome Instrument. Items are scored on a Likert scale (range 0-60). Higher scores indicate a worse health status.

Measure: Assessment of COPD via Clinical Chronic Obstructive Pulmonary Disease Questionnaire change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

Description: Memory Outcome Instrument. The maximum MMSE score is 30 points. The lower the score, the more severe the dementia.

Measure: Assessment of mental state via Mini Mental State Examination (MMSE) change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

Description: Voiding and Pain Indices. Possible score of 0-20 with higher scores denoting better function.

Measure: Assessment of interstitial cystitis via O'Leary/Sant Questionnaire change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

Description: Low Back Pain Outcome Instrument. Possible score of 0-100 with lower scores denoting better function.

Measure: Assessment of back pain via Oswestry Low Back Pain Disability Questionnaire change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

Description: Arthritis Outcome Instrument. Individual question scores are then summed to form a raw score ranging from 0 (worst) to 96 (best)

Measure: Assessment of osteoarthritis via Western Ontario and McMaster Osteoarthritis Index (WOMAC) change from baseline at 6 and 12 months.

Time: Follow up time-frames will measure changes occurring from baseline post procedure at 6 months and 12 months.

HPO Nodes


HPO

Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


HPO Nodes


Reports

Data processed on January 01, 2021.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

Drug Reports   MeSH Reports   HPO Reports  

Interventions

4,818 reports on interventions/drugs

MeSH

706 reports on MeSH terms

HPO

306 reports on HPO terms

All Terms

Alphabetical index of all Terms

Google Colab

Python example via Google Colab Notebook