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D015775: Fractures, Stress

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO


Correlated Drug Terms (6)


Name (Synonyms) Correlation
drug554 CBD Isolate Wiki 0.71
drug368 BCG vaccine (Freeze-dried) Wiki 0.71
drug2057 MinnRAP Peer Support Program Wiki 0.71
Name (Synonyms) Correlation
drug1345 Full Spectrum CBD Oil Wiki 0.71
drug416 Behaviour Change Technique Intervention to Improve Quality of Life Wiki 0.71
drug2521 Placebo Oil Wiki 0.71

Correlated MeSH Terms (11)


Name (Synonyms) Correlation
D000068376 Compassion Fatigue NIH 0.50
D000067073 Psychological Trauma NIH 0.50
D000437 Alcoholism NIH 0.41
Name (Synonyms) Correlation
D019966 Substance-Related Disorders NIH 0.35
D020920 Dyssomnias NIH 0.27
D020447 Parasomnias NIH 0.25
D040921 Stress Disorders, Traumatic NIH 0.14
D004194 Disease NIH 0.14
D013313 Stress Disorders, Post-Traumatic NIH 0.13
D013315 Stress, Psychological NIH 0.13
D001008 Anxiety Disorders NIH 0.11

Correlated HPO Terms (0)


Name (Synonyms) Correlation

Clinical Trials

Navigate: Correlations   HPO

There are 2 clinical trials


1 The Professional Peer Resilience Initiative: Leveraging a Data-Driven Model to Maximize the Resilience of Healthcare Workers During the COVID-19 Pandemic

The Professional Peer Resilience Initiative (PPRI) study is an observational study aimed at understanding how symptoms of traumatic stress and resilience evolve over time in the University of Minnesota (UMN) healthcare workforce during the coronavirus disease 2019 (COVID-19) pandemic. The study is being conducted concurrently with a UMN peer support program called the MinnRAP program and will remotely administer quality of life and mental health surveys to healthcare workers before they start the MinnRAP program and throughout their participation in the program.

NCT04396600
Conditions
  1. Stress
  2. Stress Disorder
  3. Stress, Psychological
  4. Trauma, Psychological
  5. Anxiety
  6. Anxiety State
  7. Post Traumatic Stress Disorder
  8. Secondary Traumatic Stress
  9. Professional Quality of Life
  10. Stress Related Disorder
  11. Stress Reaction
  12. Stress Risk
  13. Mental Resilience
  14. Emotional Resilience
Interventions
  1. Behavioral: MinnRAP Peer Support Program
MeSH:Disease Compassion Fatigue Fractures, Stress Anxiety Disorders Stress Disorders, Traumatic Stress Disorders, Post-Traumatic Stress, Psychological Psychological Trauma

Primary Outcomes

Description: Professional Quality of Life Questionnaire (proQOL): min score of 10; max score of 50; higher scores mean worse outcome

Measure: Change in professional quality of life

Time: Before peer support program, through study completion (an average of 7 months)

Secondary Outcomes

Description: Stress Risk & Resilience Self-Index: min score 0; max score of 12; higher scores mean worse outcome

Measure: Change in mental health symptoms and resilience markers

Time: Before peer support program, through study completion (an average of 7 months)
2 Use of CBD Oil for Reducing the Negative Emotional Impact of COVID-19: A Randomized Placebo-Controlled Clinical Trial

The overarching objective of the proposed project is to test the relative clinical efficacy of CBD isolate, full-spectrum CBD oil, and placebo in in reducing COVID-Induced stress, anxiety, depression, anger, and sleep disturbance.

NCT04603781
Conditions
  1. Anxiety Depression
  2. Alcohol Abuse
  3. Substance Abuse
  4. Anger
  5. Sleep Disturbance
  6. Stress Reaction
Interventions
  1. Dietary Supplement: CBD Isolate
  2. Dietary Supplement: Full Spectrum CBD Oil
  3. Dietary Supplement: Placebo Oil
MeSH:Dyssomnias Parasomnias Substance-Related Disorders Alcoholism Fractures, Stress

Primary Outcomes

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 0-Baseline

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 1-Treatment

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 2-Treatment

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 3-Treatment

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Weeks 4-Treatment

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 5-Treatment

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 6-Treatment

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 7-Follow-up

Description: This measure is a 23-item patient-rated emotional distress symptom scale consisting of 3 sub-factors (Depression, Anxiety, and Anger). Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Emotional Distress Index

Time: Week 8-Follow-up

Secondary Outcomes

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Depression Scale

Time: Week 0-Baseline

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Depression Scale

Time: Week 1-Treatment

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Depression Scale

Time: Week 2-Treatment

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Depression Scale

Time: Week 3-Treatment

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Depression Scale

Time: Week 4-Treatment

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Depression Scale

Time: Week 5-Follow-up

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Depression Scale

Time: Week 6-Follow-up

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anxiety Scale

Time: Week 0 Baseline

Description: This measure is an 8-item patient-rated depression symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anxiety Scale

Time: Week 1-Treatment

Description: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anxiety Scale

Time: Week 2-Treatment

Description: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anxiety Scale

Time: Week 3-Treatment

Description: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anxiety Scale

Time: Week 4-Treatment

Description: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anxiety Scale

Time: Week 5-Follow-up

Description: This measure is a 7-item patient-rated anxiety symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anxiety Scale

Time: Week 6-Follow-up

Description: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anger Scale

Time: Week 0 Baseline

Description: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anger Scale

Time: Week 1 Treatment

Description: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anger Scale

Time: Week 2 Treatment

Description: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anger Scale

Time: Week 3 Treatment

Description: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anger Scale

Time: Week 4 Treatment

Description: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anger Scale

Time: Week 5 Follow-up

Description: This measure is an 8-item patient-rated anger symptom scale. Each symptom is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Anger Scale

Time: Week 6 Follow-up

Description: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Alcohol Negative Consequences Scale

Time: Week 0 Baseline

Description: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Alcohol Negative Consequences Scale

Time: Week 1 Treatment

Description: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Alcohol Negative Consequences Scale

Time: Week 2 Treatment

Description: This measure is an 8-item patient-rated index of alcohol-related problems. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Never) to 5 (Always).

Measure: PROMIS Alcohol Negative Consequences Scale

Time: Week 3 Treatment

Description: This measure is an 8-item patient-rated index of substance use severity. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Almost Always).

Measure: PROMIS Alcohol Negative Consequences Scale

Time: Week 4 Treatment

Description: This measure is an 8-item patient-rated index of substance use severity. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Almost Always).

Measure: PROMIS Alcohol Negative Consequences Scale

Time: Week 5 Follow-up

Description: This measure is an 8-item patient-rated index of substance use severity. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Almost Always).

Measure: PROMIS Alcohol Negative Consequences Scale

Time: Week 6 Follow-up

Description: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).

Measure: PROMIS Sleep Disturbance Scale

Time: Week 0 Baseline

Description: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).

Measure: PROMIS Sleep Disturbance Scale

Time: Week 1 Treatment

Description: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).

Measure: PROMIS Sleep Disturbance Scale

Time: Week 2 Treatment

Description: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).

Measure: PROMIS Sleep Disturbance Scale

Time: Week 3 Treatment

Description: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).

Measure: PROMIS Sleep Disturbance Scale

Time: Week 4 Treatment

Description: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).

Measure: PROMIS Sleep Disturbance Scale

Time: Week 5 Follow-up

Description: This measure is an 8-item patient-rated index of sleep disturbance. Each item is rated over a 7-day period on a 5-point scale ranging from 1 (Not at all) to 5 (Very Much).

Measure: PROMIS Sleep Disturbance Scale

Time: Week 6 Follow-up

Description: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy

Measure: COVID-19 Coping Self-Efficacy

Time: Week 0 Baseline

Description: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy

Measure: COVID-19 Coping Self-Efficacy

Time: Week 1 Treatment

Description: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy

Measure: COVID-19 Coping Self-Efficacy

Time: Week 2 Treatment

Description: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy

Measure: COVID-19 Coping Self-Efficacy

Time: Week 3 Treatment

Description: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy

Measure: COVID-19 Coping Self-Efficacy

Time: Week 4 Treatment

Description: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy

Measure: COVID-19 Coping Self-Efficacy

Time: Week 5 Follow-up

Description: This measure is a 12-item author-constructed patient-rated index of COVID-19 Coping Self-Efficacy

Measure: COVID-19 Coping Self-Efficacy

Time: Week 6 Follow-up

HPO Nodes


HPO

Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


HPO Nodes


Reports

Data processed on January 01, 2021.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

Drug Reports   MeSH Reports   HPO Reports  

Interventions

4,818 reports on interventions/drugs

MeSH

706 reports on MeSH terms

HPO

306 reports on HPO terms

All Terms

Alphabetical index of all Terms

Google Colab

Python example via Google Colab Notebook