Name (Synonyms) | Correlation | |
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D045169 | Severe Acute Respiratory Syndrome NIH | 0.06 |
D018352 | Coronavirus Infections NIH | 0.05 |
Name (Synonyms) | Correlation |
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There is one clinical trial.
The purpose of this study is to learn more about infection with and recovery from the virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Some people know this virus by the name "coronavirus." It can cause the disease called COVID-19. The information gained from the study will be used to help develop better tests for SARS-CoV-2 infection and COVID-19 disease and may help in developing future vaccines and treatments by allowing researchers to determine the difference between the body's immune response to natural SARS-CoV-2 infection and immunization with a SARS-CoV-2 vaccine.
Description: Measured by peptide microarray
Measure: Humoral responses to peptide antigens derived from SARS-CoV-2 structural proteins and regions of the spike protein not present in vaccines Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by binding antibody multiplex assay (BAMA)
Measure: SARS-CoV-2-specific antibody binding response rate Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by binding antibody multiplex assay (BAMA)
Measure: SARS-CoV-2-specific antibody binding response magnitude Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by binding antibody multiplex assay (BAMA)
Measure: SARS-CoV-2-specific antibody binding response epitope specificity Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by neutralizing antibody assay (NAb)
Measure: SARS-CoV-2-specific antibody neutralization response rate Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by neutralizing antibody assay (NAb)
Measure: SARS-CoV-2-specific antibody neutralization response magnitude Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by neutralizing antibody assay (NAb)
Measure: SARS-CoV-2-specific antibody neutralization response epitope specificity Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by antibody-dependent cellular cytotoxicity assay (ADCC)
Measure: SARS-CoV-2-specific Antibody-Dependent Cellular Cytotoxicity (ADCC) response rate Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by antibody-dependent cellular cytotoxicity assay (ADCC)
Measure: SARS-CoV-2-specific Antibody-Dependent Cellular Cytotoxicity (ADCC) response magnitude Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by antibody-dependent cellular cytotoxicity assay (ADCC)
Measure: SARS-CoV-2-specific Antibody-Dependent Cellular Cytotoxicity (ADCC) response epitope specificity Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by flow cytometry
Measure: SARS-CoV-2-specific CD4+ and CD8+ T cell responses Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by flow cytometry
Measure: SARS-CoV-2-specific CD4+ and CD8+ T cell response rate Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by flow cytometry
Measure: SARS-CoV-2-specific CD4+ and CD8+ T cell response magnitude Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by flow cytometry
Measure: SARS-CoV-2-specific CD4+ and CD8+ T cell response functional profiling Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by phenotyping and monoclonal antibody isolation
Measure: SARS-CoV-2-specific memory B cell characterization Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Tabulated overall and by group
Measure: SARS-CoV-2-specific infection presentation, including clinical course, along with demographics and corresponding medical history of participants Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by real-time reverse transcription polymerase chain reaction (RT-PCR) assay
Measure: Detection of viral RNA in nasopharyngeal or nasal swab samples Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by binding antibody multiplex assay (BAMA)
Measure: Response rate of SARS-CoV-2-specific binding antibodies in nasal samples Time: Measured through participant's last visit at Month 0, 2, 4, or 12Description: Measured by binding antibody multiplex assay (BAMA)
Measure: Response magnitude of SARS-CoV-2-specific binding antibodies in nasal samples Time: Measured through participant's last visit at Month 0, 2, 4, or 12