CovidResearchTrials by Shray Alag


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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


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Name (Synonyms) Correlation

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D011014 Pneumonia NIH 0.07

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Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation - a Retrospective Multi-center Registry Study

The prognosis of patients with severe COVID-19 disease, whose lungs are so severely diseased that they need to be supported by veno-venous ECMO (extracorporeal membrane oxygenation), is difficult to assess so far. Previously published data from studies, case reports and case series describe a very high mortality in this patient collective. The significance of established clinical prognostic cores in this patient population has not been systematically investigated. This is aggravated by the fact that even at very specialized centers only very few patients from this collective are (can be) treated, so that valid investigations are only possible in a multicenter patient collective. In this registry study, all patients diagnosed with COVID-19 and treated with vv-ECMO in the centers participating in the study should be retrospectively examined. The primary aim of the study is to investigate 30-day survival, secondary objectives include the analysis of different clinical scores at the time of ECMO implantation.

NCT04405973 COVID-19 SARS-CoV 2 Extracorporeal Membrane Oxygenation ARDS Device: vv-ECMO
MeSH:Pneumonia
HPO:Pneumonia

Primary Outcomes

Description: time from ECMO-implantation to death

Measure: overall survival

Time: 30 days

Secondary Outcomes

Description: time from ECMO-implantation to ECMO-explantation

Measure: duration of ECMO treatment

Time: 30 days

Description: time from ECMO-implantation to extubation

Measure: duration of ventilation treatment

Time: 30 days

Description: time from ECMO-implantation to ICU-discharge

Measure: duration of initiation of ECMO treatment to ICU discharge

Time: 30 days


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