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drug1143 | Recombinase aided amplification (RAA) assay Wiki | 1.00 |
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There is one clinical trial.
Due to the rapidly developing nature and severity of the COVID-19 pandemic, clinical trials involving a repurposed drug approach are the best option for rapidly identifying an effective COVID-19 therapeutic. The investigators propose to evaluate the efficacy of Montelukast in attenuating cytokine storm syndrome and ARDS via a randomized, blinded, placebo-controlled clinical trial. Specifically, our primary objective is comparing the efficacy of low-dose Montelukast versus placebo in reducing the risk of acute care visits and hospital admissions among COVID-19 positive patients in the general population.
Description: acute care use that includes a composite outcome comprised of being hospitalized and/or having visited an emergency room during follow-up.
Measure: Emergency Room Visits and Hospitalizations Time: 12 weeksDescription: The number of emergency room visits
Measure: Emergency room visit count Time: 12 weeksDescription: The number of hospitalizations
Measure: Hospitalization admission count Time: 12 weeksDescription: Complications will be defined as a composite endpoint including pneumonia, ARDS sepsis/septic shock, cardiomyopathy or arrhythmia, acute kidney injury, and secondary bacterial infections.
Measure: Time to other serious COVID-19 complications Time: 12 weeks