Name (Synonyms) | Correlation |
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Name (Synonyms) | Correlation |
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There is one clinical trial.
We aim to investigate whether the use of Continuous Positive Airway Pressure using a Helmet device (Helmet CPAP) will increase the number of days alive and free of ventilator within 28 days compared to the use of a High Flow Nasal Cannula (HFNC) in patients admitted to Helsingborg Hospital, Sweden, suffering from COVID-19 and an acute hypoxic respiratory failure.
Description: Number of days alive and free of mechanical ventilation within 28 days. Patients who die within 28 days will be counted as 0 VFD. Time in ventilator will be counted in hours and rounded to whole days.
Measure: Ventilator-Free Days (VFD) Time: 28 daysDescription: Peripheral oxygen saturation divided by fraction of inspired oxygen
Measure: SpO2/FiO2-ratio Time: 1 hour after randomisationDescription: Visual scale (1-10)
Measure: Patient comfort Time: 24 hours after randomisationDescription: Min 0, Max 1
Measure: Frequency of endotracheal intubation Time: 28 daysDescription: Defined as pCO2 > 6 kPa in a venous blood gas. Min 0, Max ∞
Measure: Frequency of carbon dioxide rebreathing Time: 28 daysDescription: All-cause mortality. (180 days endpoint not in primary publication)
Measure: Days alive within Time: 28 days and 180 days