Correlated Drug Terms (1)

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	Name (Synonyms)	Correlation
drug348	Conestat alfa Wiki	1.00

Correlated MeSH Terms (4)

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	Name (Synonyms)	Correlation
D003141	Communicable Diseases NIH	0.10
D007239	Infection NIH	0.07
D045169	Severe Acute Respiratory Syndrome NIH	0.06
D018352	Coronavirus Infections NIH	0.05

Correlated HPO Terms (0)

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	Name (Synonyms)	Correlation

Primary Outcomes

Description: Dead/alive

Measure: Vital status

Time: Day 8

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Description: Yes/no

Measure: Patient requiring more than 3 liters of oxygen to maintain a saturation >95% (intensive care unit or resuscitation department)

Time: Day 8

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Description: % ground glass and condensation calculated by deep learning

Measure: Percentage of lung affected on CT

Time: Day 0

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Description: % calculated by deep learning

Measure: Percentage of lung affected by ground glass opacity on scan

Time: Day 0

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Description: % calculated by deep learning

Measure: Percentage of lung affected by condensation on scan

Time: Day 0

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Secondary Outcomes

Description: Dead/alive

Measure: Vital status

Time: Day 16

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Description: Dead/alive

Measure: Vital status

Time: Day 30

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Description: Days

Measure: Length of hospitalization

Time: Maximum 30 days

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Description: Yes/no

Measure: rehospitalization

Time: Day 30

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Description: Days

Measure: Duration of intubation

Time: Day 30

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Description: % ground glass and condensation calculated by deep learning

Measure: Percentage of lung affected on CT

Time: Day 16

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Description: % calculated by deep learning

Measure: Percentage of lung affected by ground glass opacity on scan

Time: Day 16

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Description: % calculated by deep learning

Measure: Percentage of lung affected by condensation on scan

Time: Day 16

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Description: Speed of image loading and image processing depending of brand of scanner

Measure: Software operating time

Time: End of study (August 2020)

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Description: mg/L

Measure: C-reactive protein levels

Time: Admission Day 0

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Description: U/L

Measure: lactate dehydrogenase

Time: Admission Day 0

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Description: g/L

Measure: lymphocytemia

Time: Admission Day 0

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Description: µg/L

Measure: D Dimers level

Time: Admission Day 0

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Description: Days

Measure: Time until onset of symptoms

Time: Admission Day 0

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Description: Hours

Measure: Time between RT-PCR positive results and first scan

Time: Admission Day 0

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Description: Years

Measure: Age

Time: Admission Day 0

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Description: Yes/no:

Measure: BMI> 30

Time: Admission Day 0

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Description: Yes/no: hypertension, coronary artery disease, congestive heart failure, cardiac arrhythmia

Measure: Medical history of cardiovascular disease

Time: Admission Day 0

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Description: Yes/no

Measure: Diabetes

Time: Admission Day 0

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Description: Yes/no: Chronic obstructive pulmonary disease, chronic respiratory failure

Measure: Medical history of respiratory disease

Time: Admission Day 0

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Description: Yes/no: steroid use, pre-existing immunological condition, current chemotherapy for cancer

Measure: Medical history of immunosuppressed condition

Time: Admission Day 0

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Description: Yes/no:

Measure: Current or previous history of smoking

Time: Admission Day 0

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Description: Deep learning algorithm

Measure: Calculate a prognostic score from clinical, biological and CT parameters

Time: Day 8

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Description: Deep learning algorithm

Measure: Calculate a prognostic score from clinical and biological parameters only

Time: Day 8

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Measure: Compare receiver operating curves of prognostic scores with and without CT parameters

Time: Day 8

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