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    infection

    This report considers only clinical trials that are associated with COVID-19 vaccines.

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (3)


    Name (Synonyms) Correlation
    drug2936 SARS-CoV-2 vaccine (inactivated) Wiki 1.00
    drug1366 Gam-COVID-Vac Wiki 0.38
    drug2490 Placebo Wiki 0.13

    Correlated MeSH Terms (1)


    Name (Synonyms) Correlation
    D007239 Infection NIH 0.24

    Correlated HPO Terms (0)


    Name (Synonyms) Correlation

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 A Phase III, Observer-blind, Randomized, Placebo-controlled Study of the Efficacy, Safety and Immunogenicity of SARS-CoV-2 Inactivated Vaccine in Healthy Adults Aged 18-59 Years in Indonesia

    This phase III trial aims to assess the efficacy, safety and immunogenicity of SARS-CoV-2 Vaccine (inactivated) and lot-to-lot consistency evaluation

    NCT04508075
    Conditions
    1. SARS-CoV2 Infection
    Interventions
    1. Biological: SARS-CoV-2 vaccine (inactivated)
    2. Biological: Placebo
    MeSH:Infection

    Primary Outcomes

    Description: Percentage of laboratory-confirmed COVID-19 cases

    Measure: Incidence of laboratory-confirmed COVID-19 after the second dose

    Time: 14 days to 6 months after the second dose

    Secondary Outcomes

    Description: Percentage of suspected COVID-19 cases

    Measure: Incidence of suspected COVID-19 cases

    Time: within 14 days to 6 months after the second dose.

    Description: Percentage of laboratory-confirmed cases (severe, critical, death)

    Measure: Incidence of laboratory-confirmed cases (severe, critical and death)

    Time: within 14 days to 6 months after the second dose

    Description: Percentage of subjects with four-fold increasing anti-S antibody IgG titer (ELISA) compare to baseline and between batches

    Measure: Seroconversion rate anti-S antibody IgG titer (ELISA)

    Time: 14 days after two doses of vaccination

    Description: Percentage of subjects with four-fold increasing anti-S antibody IgG titer (ELISA) compare to baseline and between batches

    Measure: Seroconversion rate anti-S antibody IgG titer (ELISA)

    Time: 6 months after two doses of vaccination

    Description: Percentage of subjects with four-fold increasing serum neutralizing antibody compared to baseline and between batches

    Measure: Seropositive rate of neutralizing antibodies

    Time: 14 days after two doses of vaccination

    Description: Percentage of subjects with four-fold increasing serum neutralizing antibody compared to baseline and between batches

    Measure: Seropositive rate of neutralizing antibodies

    Time: 6 months after two doses of vaccination

    Other Outcomes

    Description: Number of Local reactions and systemic events

    Measure: Local reaction and systemic events

    Time: 30 minutes to 14 days after each vaccination

    Description: Number of Local reactions and systemic events

    Measure: Local reaction and systemic events occurring after the last vaccination

    Time: 14 days to 28 days following last vaccination

    Description: Number of any SAE occur

    Measure: Serious adverse events during study

    Time: 6 months after the last dose

    No related HPO nodes (Using clinical trials)


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    No related HPO nodes (Using clinical trials)


    Reports

    Data processed on January 01, 2021.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

    Drug Reports   MeSH Reports   HPO Reports  

    Interventions

    4,818 reports on interventions/drugs

    MeSH

    706 reports on MeSH terms

    HPO

    306 reports on HPO terms

    All Terms

    Alphabetical index of all Terms

    Google Colab

    Python example via Google Colab Notebook