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    Covid19 Vaccine

    This report considers only clinical trials that are associated with COVID-19 vaccines.

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (5)


    Name (Synonyms) Correlation
    drug1359 GM-CSF Wiki 1.00
    drug1869 Low Dose of KBP-COVID-19 Wiki 1.00
    drug1447 High Dose of KBP-COVID-19 Wiki 1.00
    Name (Synonyms) Correlation
    drug119 AV-COVID-19 Wiki 0.58
    drug2490 Placebo Wiki 0.13

    Correlated MeSH Terms (1)


    Name (Synonyms) Correlation
    D007239 Infection NIH 0.24

    Correlated HPO Terms (0)


    Name (Synonyms) Correlation

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 A First-in-human, Observer-blinded, Randomized, Placebo-controlled, Parallel Group Study to Evaluate the Safety and Immunogenicity of KBP-COVID-19 SARS-CoV-2 Vaccine With Adjuvant in Healthy Seronegative Adults Aged 18-49 and 50-70

    This is an First In Human (FIH), observer-blinded, randomized, placebo-controlled, parallel group study to evaluate the safety and immunogenicity of KBP-COVID-19 vaccine in healthy CoV-2seronegative adult subjects in 2 age groups, Part A (18-49 years) and Part B (50-70 years).

    NCT04473690
    Conditions
    1. Covid19
    Interventions
    1. Biological: Low Dose of KBP-COVID-19
    2. Biological: High Dose of KBP-COVID-19
    3. Biological: Placebo

    Primary Outcomes

    Description: Occurrence of Adverse Events

    Measure: Solicited Administration site reactions

    Time: 7 days after vaccination

    Description: Occurrence of Adverse Events

    Measure: Solicited systemic events

    Time: 7 days after vaccination

    Secondary Outcomes

    Description: Safety Endpoints

    Measure: Unsolicited Adverse Events and medically attended adverse events

    Time: 43 days after vaccination

    Description: Safety Endpoints

    Measure: Serious Adverse Events, Medically Attended Adverse Events and New Onset Chronic Diseae

    Time: 365 days after vaccination

    Description: Immunogenicity

    Measure: Vaccine ELISA and neutralizing antibody titers for each treatment group

    Time: Baseline, Day 8, 15, 22, 29, 43, 90, 181, 273, 365

    Description: Immunogenicity

    Measure: Seroconversion rates

    Time: Days 8, 15, 22, 29, 43, 90, 181, 273, 365

    No related HPO nodes (Using clinical trials)


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    No related HPO nodes (Using clinical trials)


    Reports

    Data processed on January 01, 2021.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

    Drug Reports   MeSH Reports   HPO Reports  

    Interventions

    4,818 reports on interventions/drugs

    MeSH

    706 reports on MeSH terms

    HPO

    306 reports on HPO terms

    All Terms

    Alphabetical index of all Terms

    Google Colab

    Python example via Google Colab Notebook