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    Inactivated SARS-CoV-2 Vaccine

    This report considers only clinical trials that are associated with COVID-19 vaccines.

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (5)


    Name (Synonyms) Correlation
    drug1818 Licensed seasonal influenza vaccine Wiki 1.00
    drug2570 Placebo/Aluminum Adjuvant of Inactivated SARS-CoV-2 vaccine Wiki 1.00
    drug2924 SARS-CoV-2 rS/Matrix M1-Adjuvant Wiki 1.00
    Name (Synonyms) Correlation
    drug1643 Inactivated SARS-CoV-2 vaccine (Vero cell) Wiki 1.00
    drug2490 Placebo Wiki 0.13

    Correlated MeSH Terms (1)


    Name (Synonyms) Correlation
    D014777 Virus Diseases NIH 0.41

    Correlated HPO Terms (0)


    Name (Synonyms) Correlation

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 Randomized, Double Blind, Placebo Parallel-controlled Phase III Clinical Trial to Evaluate the Efficacy, Immunogenicity and Safety of the Inactivated SARS-CoV-2 Vaccine (Vero Cell) in Argentine Healthy Population Aged Between 18 and 85 Years

    This is a randomized, double blind, placebo parallel-controlled phase III clinical trial to evaluate the efficacy, immunogenicity and safety of the inactivated SARS-CoV-2 Vaccine (Vero cell) in Argentine healthy population aged between 18 and 85 years old.

    NCT04560881
    Conditions
    1. COVID-19 Virus Infection
    Interventions
    1. Biological: Inactivated SARS-CoV-2 vaccine (Vero cell)
    2. Biological: Placebo/Aluminum Adjuvant of Inactivated SARS-CoV-2 vaccine
    MeSH:Virus Diseases

    Primary Outcomes

    Description: All confirmed COVID -19 cases 14 days after the full course of vaccination among healthy population aged between 18 and 85 years old.

    Measure: Incidence of COVID-19 cases after two-doses of vaccination

    Time: 14 days after the full course of vaccination

    Secondary Outcomes

    Measure: The 4-fold increase rate of anti-SARS-CoV-2 neutralizing antibody

    Time: 14 days after 2-dose of immunization and 28 days after full course of immunization

    Measure: The Geometric Mean Titer (GMT) of anti-SARS-CoV-2 neutralizing antibody

    Time: 14 days after 2-dose of immunization and 28 days after full course of immunization

    Measure: The Geometric Mean Increase (GMI) of anti-SARS-CoV-2 neutralizing antibody

    Time: 14 days after 2-dose of immunization and 28 days after full course of immunization

    Measure: Incidence of any adverse reactions/events

    Time: Within 30 minutes after each dose of vaccine

    Measure: Incidence of adverse reactions/events

    Time: 0 ~ 21/28 days after each dose of vaccine

    Measure: Incidence of serious adverse events (SAE)

    Time: From the beginning of the first dose to 12 months after the whole course of immunization

    Other Outcomes

    Description: The protective level of Anti-SARS-CoV-2 NtAbs

    Measure: Anti-SARS-CoV-2 neutralizing antobody (NtAb) (immunological surrogate endpoint)

    Time: 14 days after 2-dose of immunization.

    No related HPO nodes (Using clinical trials)


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    No related HPO nodes (Using clinical trials)


    Reports

    Data processed on January 01, 2021.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

    Drug Reports   MeSH Reports   HPO Reports  

    Interventions

    4,818 reports on interventions/drugs

    MeSH

    706 reports on MeSH terms

    HPO

    306 reports on HPO terms

    All Terms

    Alphabetical index of all Terms

    Google Colab

    Python example via Google Colab Notebook