The purpose of this study is to evaluate if a diet with a high content of phytoestrogens can slow down the prostate tumor proliferation. Phytoestrogens are found in food items such as soy, rye, and seeds. Two hundred thirty men with prostate cancer will be included in the study and followed until surgery (at least 6 weeks). Half of the study participants will receive general information about healthy food choices and a package of foods with high content of phytoestrogens to add to their food. The other half will get the same information but not receive the food-package.

NCT02759380

Conditions

1. Prostate Cancer

Interventions

1. Other: Phytoestrogen-rich foods

MeSH:Prostatic Neoplasms

HPO:Prostate cancer Prostate neoplasm

The men will be divided into two subgroups, those bearing TT or TC/CC alleles, of the single-nucleotide polymorphism (SNP) rs2987983-13950 T/C in the ERß-gene, in which the hypothesis will be tested.

The investigators found in earlier studies that approximately 42 % of the male population are heterozygous or homozygous for the variant allele (TC/CC) of the ERβ promoter region SNP (rs2987983-13950 T/C) and 58 % homozygous for the wild type allele (TT).