SNPMiner Trials by Shray Alag

 rs12979860 (38) rs6971 (31) rs9939609 (11) rs6265 (11) rs738409 (11) rs7903146 (8) rs4680 (8) rs8099917 (8) rs11200638 (6) rs429358 (6) rs10490924 (6) rs7412 (6) rs16969968 (5) rs25531 (5) rs1801133 (5) rs1800497 (5) rs1799971 (4) rs4244285 (4) rs2832407 (4) rs1045642 (4) rs1544410 (4) rs10033464 (3) rs1761667 (3) rs6166 (3) rs1042713 (3) rs2023239 (3) rs1051730 (3) rs174537 (3) rs1006737 (3) rs2230199 (3) rs1128503 (3) rs2231142 (3) rs10455872 (3) rs6313 (3) rs1061170 (3) rs776746 (3) rs4588 (3) rs2069514 (2) rs1799963 (2) rs9332739 (2) rs2032582 (2) rs3745274 (2) rs6295 (2) rs12936231 (2) rs6280 (2) rs7103572 (2) rs35599367 (2) rs13266634 (2) rs1410996 (2) rs6025 (2) rs4129267 (2) rs70991108 (2) rs174547 (2) rs1127354 (2) rs362331 (2) rs53576 (2) rs35705950 (2) rs641153 (2) rs1695 (2) rs2234246 (2) rs10741657 (2) rs1800955 (2) rs2106261 (2) rs4149056 (2) rs2234237 (2) rs362307 (2) rs3808607 (2) rs1828591 (2) rs1800470 (2) rs1024611 (2) rs12785878 (2) rs3751143 (2) rs762551 (2) rs165599 (2) rs2200733 (2) rs1150226 (2) rs4646 (2) rs3798220 (2) rs3813929 (2) rs25487 (2) rs10830963 (2) rs2472677 (2) rs2281135 (2) rs4986893 (2) rs3211938 (2) rs8050136 (2) rs1801131 (2) rs855791 (2) rs5219 (2) rs4646437 (2) rs2228570 (2) rs2070744 (1) rs1017783 (1) rs4986938 (1) rs2297201 (1) rs377637047 (1) rs2298771 (1) rs1799724 (1) rs7799039 (1) rs7041 (1) rs7586970 (1) rs8175347 (1) rs1799853 (1) rs1799732 (1) rs6190 (1) rs9344 (1) rs3918242 (1) rs7549785 (1) rs3796529 (1) rs10835211 (1) rs3570920 (1) rs1998199 (1) rs2274333 (1) rs78408340 (1) rs28363170 (1) rs2987983 (1) rs833069rs (1) rs41524547 (1) rs12529 (1) rs1042522 (1) rs11958940 (1) rs34743033 (1) rs13058338 (1) rs2043211 (1) rs5082 (1) rs6739405 (1) rs4958351 (1) rs6296 (1) rs3761624 (1) rs13333226 (1) rs179008 (1) rs4802703 (1) rs547154 (1) rs7521902 (1) rs867186 (1) rs641738 (1) rs2540923 (1) rs2297480 (1) rs1672717 (1) rs4869676 (1) rs10163409 (1) rs4869675 (1) rs236114 (1) rs6165 (1) rs700518 (1) rs11615 (1) rs3025039 (1) rs11795404 (1) rs3816527 (1) rs999737 (1) rs10836235 (1) rs1256049 (1) rs27072 (1) rs614367 (1) rs12434438 (1) rs137852620 (1) rs3853445 (1) rs35874116 (1) rs3747158 (1) rs1799930 (1) rs20432111 (1) rs5068 (1) rs1310182 (1) rs7604448 (1) rs20455 (1) rs1042714 (1) rs3114018 (1) rs2269273 (1) rs6269 (1) rs1042711 (1) rs2269272 (1) rs861529 (1) rs18011131 (1) rs9340799 (1) rs2235046 (1) rs316019 (1) rs10995190 (1) rs1260326 (1) rs4570625 (1) rs1042718 (1) rs2250656 (1) rs731236 (1) rs2307227 (1) rs41524745 (1) rs6841581 (1) rs1049353 (1) rs244072 (1) rs13208321 (1) rs35463555 (1) rs1052533 (1) rs3918226 (1) rs61747728 (1) rs4073 (1) rs904627 (1) rs2295190 (1) rs2053044 (1) rs10153820 (1) rs754203 (1) rs547987105 (1) rs2562582 (1) rs2494732 (1) rs619824 (1) rs8176528 (1) rs1360780 (1) rs833061 (1) rs16147 (1) rs72552763 (1) rs9679162 (1) rs2280964 (1) rs7975232 (1) rs1726866 (1) rs10813831 (1) rs6504950 (1) rs806380 (1) rs6856901 (1) rs45511401 (1) rs573562920 (1) rs3210140 (1) rs887829 (1) rs7221412 (1) rs628031 (1) rs20417 (1) rs2687133 (1) rs7579240 (1) rs174535 (1) rs679620 (1) rs2060793 (1) rs806377 (1) rs1800629 (1) rs66554220 (1) rs1800624 (1) rs3750920 (1) rs1042522s (1) rs10246939 (1) rs2550946 (1) rs2279744 (1) rs909253 (1) rs2071559 (1) rs1024582 (1) rs10930214 (1) rs13387042 (1) rs17601696 (1) rs2046210 (1) rs8065080 (1) rs4604006 (1) rs2002555 (1) rs757110 (1) rs2910164 (1) rs1061325 (1) rs4950928 (1) rs10994336 (1) rs11548193 (1) rs73049 (1) rs9457827 (1) rs1883112 (1) rs17782313 (1) rs12459419 (1) rs150018775 (1) rs708272 (1) rs2275163 (1) rs12762549 (1) rs10941679 (1) rs699947 (1) rs2895795 (1) rs2697153 (1) rs45500792 (1) rs30461 (1) rs550842646 (1) rs2067085 (1) rs1051931 (1) rs333 (1) rs3853839 (1) rs956572 (1) rs4900442 (1) rs3755166 (1) rs324015 (1) rs271924 (1) rs3758673 (1) rs3758674 (1) rs11572080 (1) rs4151667 (1) rs894278 (1) rs10859871 (1) rs2294918 (1) rs933226 (1) rs9657182 (1) rs571312 (1) rs20715592 (1) rs12201199 (1) rs1786378374 (1) rs13376333 (1) rs17070145 (1) rs17561 (1) rs34489327 (1) rs7571842 (1) rs11133360 (1) rs2235321 (1) rs678849 (1) rs8069645 (1) rs35059413 (1) rs6454674 (1) rs2853884 (1) rs737865 (1) rs183489969 (1) rs7333181 (1) rs1143623 (1) rs71647871 (1) rs4149032 (1) rs17037122 (1) rs1062613 (1) rs2516513 (1) rs1048661 (1) rs11126727 (1) rs11568821 (1) rs1049524 (1) rs11568820 (1) rs1049522 (1) rs172378 (1) rs10994133 (1) rs924607 (1) rs2488457 (1) rs1143633 (1) rs11039155 (1) rs1143634 (1) rs2464266 (1) rs396991 (1) rs562696473 (1) rs11126731 (1) rs8105790 (1) rs10509681 (1) rs12041331 (1) rs1805010 (1) rs6013897 (1) rs16139 (1) rs2234693 (1) rs35652124 (1) rs4693608 (1) rs961360700 (1) rs2305948 (1) rs4343 (1) rs5743844 (1) rs4883263 (1) rs10033900 (1) rs4883264 (1) rs2243250 (1) rs2241193 (1) rs17614942 (1) rs2383206 (1) rs1800592 (1) rs613872 (1) rs4803217 (1) rs11031006 (1) rs1047768 (1) rs12208357 (1) rs4488809 (1) rs1800588 (1) rs2227902 (1) rs1549339 (1) rs3184504 (1) rs2248949 (1) rs222797 (1) rs1643649 (1) rs4803455 (1) rs2853564 (1) rs780094 (1) rs2231137 (1) rs6434222 (1) rs3825942 (1) rs112735431 (1) rs751402 (1) rs9701796 (1) rs1202167 (1) rs1202168 (1) rs1202169 (1) rs12472215 (1) rs4311 (1) rs2279238 (1) rs3766404 (1) rs7349683 (1) rs3781727 (1) rs1800450 (1) rs7157609 (1) rs529802001 (1) rs2257401 (1) rs3817198 (1) rs1217414 (1) rs1045485 (1) rs2278392 (1) rs2476601 (1) rs7993418 (1) rs13181 (1) rs4673 (1) rs2097432 (1) rs324011 (1) rs1079598 (1) rs1800566 (1) rs1800682 (1) rs603965 (1) rs993607 (1) rs1790349 (1) rs1044396 (1) rs3742376 (1) rs6592052 (1) rs9332377 (1) rs16111115 (1) rs11559024 (1) rs1149222 (1) rs11870474 (1) rs25331 (1) rs2929116 (1) rs2929115 (1) rs7961953 (1) rs2242480 (1) rs4532 (1) rs222747 (1) rs105173 (1) rs2165241 (1) rs1800795 (1) rs2075606 (1) rs11648486 (1) rs35874116rs (1) rs4795541 (1) rs2282679 (1) rs7853758 (1) rs1504982 (1) rs1176713 (1) rs11249433 (1) rs12467815 (1) rs10524523 (1) rs4880 (1) rs12760457 (1) rs2062305 (1) rs3828057 (1) rs3790515 (1) rs11687951 (1) rs1800896 (1) rs254093 (1) rs4994 (1) rs4633 (1) rs1885988 (1) rs11099592 (1) rs6843082 (1) rs17611 (1) rs2228171 (1) rs1042173 (1) rs41432149 (1) rs926198 (1) rs12992677 (1) rs2305619 (1) rs1800888 (1) rs61729512 (1) rs2266782 (1) rs1653624 (1) rs664393 (1) rs2246704 (1) rs11959427 (1) rs4848306 (1) rs3765467 (1) rs2246709 (1) rs2089760 (1) rs2180439 (1) rs2242447 (1) rs2981582 (1) rs12654788 (1) rs5275 (1) rs1053230 (1) rs1906591 (1) rs2010963 (1) rs11102930 (1) rs2601126 (1) rs2854116 (1) rs2854117 (1) rs16944 (1) rs17778257 (1) rs16942 (1) rs1801282 (1) rs5751876 (1) rs762251 (1) rs3803662 (1) rs10264272 (1) rs28399433 (1) rs230561 (1) rs12654778 (1) rs4364254 (1) rs10177833 (1) rs2238071 (1) rs1801275 (1) rs10766197 (1) rs704010 (1) rs10937405 (1) rs2228480 (1) rs9526240 (1) rs17570669 (1) rs10407022 (1) rs4612666 (1) rs6746030 (1) rs889312 (1) rs243866 (1) rs2740565 (1) rs1558902 (1) rs8192620 (1) rs10865801 (1) rs58542926 (1) rs3789604 (1) rs1801260 (1) rs2273773 (1) rs10757274 (1) rs573112 (1) rs2244613 (1) rs10757278 (1) rs6330 (1) rs1056892 (1) rs11931074 (1) rs2075252 (1) rs1297860 (1) rs28459296 (1) rs2380205 (1) rs780094s (1) rs9557195 (1) rs11045585 (1) rs1801253 (1) rs1801132 (1) rs11569562 (1) rs2104772 (1) rs15524 (1) rs2854275 (1) rs2066842 (1) rs12255372 (1) rs6323 (1) rs1057910 (1) rs1051375 (1) rs544684689 (1) rs2234237r25r (1) rs6318 (1) rs9826 (1) rs7120118 (1) rs12356193 (1) rs8111699 (1) rs7270101 (1) rs17042171 (1) rs1062033 (1) rs553668 (1) rs185670819 (1) rs1405655 (1) rs6311 (1) rs518147 (1) rs10401969 (1) rs4516035 (1) rs33996649 (1) rs10276036 (1) rs1465952 (1) rs2232618 (1) rs549927573 (1) rs41308230 (1) rs2293152 (1) rs2237060 (1) rs5215 (1) rs4820059 (1) rs12329760 (1) rs12676 (1) rs11083519 (1) rs16874954 (1) rs35597368 (1) rs1799983 (1) rs5573 (1) rs2229774 (1) rs2731886 (1) rs5574 (1) rs2302616 (1) rs12221497 (1) rs4973768 (1) rs5569 (1) rs2032892 (1) rs13281615 (1) rs4820268 (1) rs10079250 (1) rs1799750 (1) rs9366637 (1) rs4148738 (1) rs10456542 (1) rs25648 (1) rs9984723 (1) rs766996587 (1) rs2398162 (1) rs7291050 (1) rs1011970 (1) rs4253728 (1) rs12143842 (1)

SNPMiner SNPMiner Trials (Home Page)

Report for SNP rs4803455

Developed by Shray Alag, 2020-2021.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials

1 TGFB1 and LAMA1 Gene Polymorphisms in Turkish Children With High Myopia

The investigators aimed to investigate TGFB1 and LAMA1 gene polymorphisms in children with high myopia in order to determine the genetic basis of large myopic shifts causing severe visual impairment and complications. Seventy-four children with high myopia (≥6 diopters [D]; study group) and 77 emmetropic children (±0.5D; control group) were included. Genetic and polymorphism analyses were performed in the Medical Genetics Laboratory using DNA purified from the patients' blood samples.

NCT03451877
Conditions
  1. High Myopia
  2. Gene Mutations
Interventions
  1. Genetic: TGFB1 AND LAMA1 GENE POLYMORPHISMS
MeSH:Myopia
HPO:Myopia

evaluated polymorphisms in the LAMA1 (rs2089760) and TGFB1 (rs4803455) genes in children younger than 13 years of age with ≥6 D myopia.

Primary Outcomes

Description: evaluated polymorphisms in the LAMA1 (rs2089760) and TGFB1 (rs4803455) genes in children younger than 13 years of age with ≥6 D myopia

Measure: Genetic basis of high myopia

Time: 4 years

HPO Nodes

HP:0000545: Myopia
Genes 489
VCAN COL2A1 TCF4 TIMM8A B3GLCT HSPG2 UCHL1 ATP6V0A2 C12ORF57 TRAPPC11 GTF2IRD1 RPGR POMGNT1 POLR3B BBS1 POLR1C SLC25A4 ASXL1 KIF11 ARID1B PUF60 HACE1 SETD5 POMGNT1 RPL10 PLOD1 EIF2S3 AKT1 FBN1 USP9X CTNNB1 SCO2 ANTXR1 PTEN HUWE1 FKTN PTEN MSX2 UBE3A COL2A1 FKRP VARS1 PLOD1 POMT2 PURA CDC45 RPGR CLIP2 BMP4 ADAMTS10 GPAA1 ANKRD11 TARS1 PIK3R1 NYX FKRP B3GALNT2 ATP6V0A2 VPS13B ABCC6 TKFC MYO5A PMM2 NRAS BRAF CDK8 LARGE1 ELN PTEN CNGA3 CYP1B1 B3GALT6 PRDM5 WAC COL11A1 USP9X P4HTM ADAMTSL1 SEC23B COL2A1 SON ATP6V0A2 COL2A1 AKT1 NIPBL COX7B SOX5 MBD5 TWIST2 COL11A1 LTBP2 CACNA1F GJA1 TMEM63A KRAS COL2A1 PAX2 NPAP1 IFT122 GNPTG VPS13B COL2A1 POMT2 GJA1 CBS ADAMTSL4 PACS2 FKTN P3H2 ATP6V1E1 COL5A1 IFIH1 DAG1 MAP2K2 ARR3 SMC3 CHST14 SMARCAL1 LTBP2 NFIX SNORD115-1 LIG4 FKTN PPP2R5D GMPPB CHM EMC1 CLDN19 ENPP1 GPR179 MKRN3-AS1 EXOSC2 CRYGC POMT2 GNB3 PTPN11 FANCI IGF1 PRDM5 ELP1 TAF1 BTD GTPBP2 KMT2A ZNF469 PWRN1 COL11A1 IPW PRIMPOL TBC1D7 CBS KAT6A MBTPS2 ZSWIM6 NT5C2 SNRPN ZEB2 TYR MYOC GLE1 COL2A1 COL2A1 DNAJC21 RAI1 SH2B1 LAMA1 AP1B1 KCNH1 NBAS KRAS TBC1D24 GJC2 TRAPPC11 COL11A1 IFT52 POLR3B FKBP14 OPN1LW ASXL1 GMPPB GRK1 CASK KIAA0586 SDHB POMT2 SLC39A5 GMPPB USH2A CANT1 XYLT2 GPR179 PIK3CA GRM6 NOTCH2 SKI AKT1 HTT GPAA1 RAD21 SOX5 LOX ZNF469 ZSWIM6 POMGNT1 ADAMTS10 CRYGD TEAD1 FKRP POLR3A MAGEL2 LRIT3 MYO7A KLHL7 KLLN RMRP PDZD7 POLR3A MAN2B1 ZNF408 HS6ST2 PTEN ADAMTS17 GLRB PWAR1 PDE6H WAC TCF4 LRIT3 ADGRV1 IFT43 CNGB3 LAMB2 WDR19 CLDN16 THG1L FBN1 NIPBL KCNV2 PLOD3 DSE TCF20 MKRN3 COL4A5 SLC24A1 FKRP NSUN2 LRP2 CPSF1 TRNT1 OAT MC1R DYRK1A ALDH3A2 BRAF MYOC NONO COL9A2 EXOC6B FKBP14 COL4A3 APC2 FGFR3 FBN1 IFT122 CABP4 POMT2 EPHA2 CYP4V2 NSD1 SLC2A10 COL2A1 ATP6V1A AEBP1 UBE3B TBL2 PIGT COL2A1 COL2A1 ATRX HERC1 TULP1 FKRP COL11A1 POMT1 LOXL3 NDUFB11 MPLKIP GNAT1 CCNQ PSMD12 RFC2 SNORD116-1 MADD LIMK1 BMP4 LAMA1 POMK B3GALT6 ATAD3A CACNA1F ZNF644 POMGNT1 OPN1MW COL2A1 COL1A2 COL9A3 TBC1D24 WDR35 RP2 GNAT2 FKTN RP1 COL18A1 MAGEL2 NSD1 CRYAA RHO RNF113A BRAF HNRNPK COL12A1 POMGNT1 IQSEC2 RIN2 RHOA MAP2K1 LRRC32 C8ORF37 DEAF1 COL9A2 AFF4 ERCC2 LTBP2 EMC1 TRIT1 POGZ FBXW11 BPTF TFAP2B NT5C2 AGK ARCN1 USF3 SNRPN TCF4 BCL11B AMMECR1 GJA8 OPTN PIK3CA DPYD LARGE1 TRPM1 POGZ CRIPT POMT2 KDM5C CHST14 SDHC WDR19 GZF1 GNB3 HACE1 RPL10 B3GALT6 WDR26 ACOX1 SETD5 MAF SMS DYRK1A TFAP2A PCYT1A FBN1 ABCC6 CCDC28B GTF2I FBN2 POLR3A ELOVL4 OAT SMS GRM6 TRPM1 MED13L EED MAP2K2 GTF2H5 NR2F1 LRP2 POMT1 CRYBB2 SETD5 ARL6 CSPP1 KIF11 HADHA THOC6 AGBL5 RAI1 MED12L HNRNPK COL4A3 XYLT1 EFL1 ZEB2 KDM5B SMC1A MAP2K1 NDN CRYBA2 SLC12A6 SETD2 COL9A1 POMT1 SLITRK6 ERBB3 SKI RAB28 ATAD3A SAG OCA2 BFSP2 LRPAP1 SMC3 PDE6C YME1L1 FBN1 CACNA2D4 RECQL4 PDE6B PACS1 TTC8 CAMK2G PRPS1 CACNA1F TMEM94 JAG1 BLOC1S3 RERE COL2A1 COL9A1 HDAC8 HERC2 COL4A4 COL4A1 TUB WHRN ACSL4 COL18A1 CACNA1F FBN1 CRYBA4 P4HA2 RBM10 ATF6 B3GALNT2 MAGEL2 HSPG2 COL2A1 AGK ADAMTS2 CHMP1A AMMECR1 ALDH18A1 MIR140 SDHD AHDC1 GTF2E2 BAZ1B KCNE5 MAN2B1 HDAC8 USP7 CRYBB1 POMT1 POMT1 FLII ERCC3 CNGB3 LARGE1 GPR143 DAG1 NYX COL11A1 CLDN19 NONO IRX5 UBE3B
Protein Mutations 0
SNP 2
rs2089760 rs4803455