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  • HP:0006775: Multiple myeloma
  • Pneumonia (361) Abnormality of the cardiovascular system (36) Respiratory tract infection (36) Neoplasm (29) Hypoxemia (28) Diabetes mellitus (25) Depressivity (24) Thromboembolism (23) Acute kidney injury (22) Abnormal lung morphology (21) Anosmia (19) Hypertension (18) Abnormality of coagulation (15) Pulmonary embolism (15) Pulmonary fibrosis (15) Stroke (14) Arthritis (14) Interstitial pneumonitis (14) Myocardial infarction (12) Type II diabetes mellitus (12) Deep venous thrombosis (11) Rheumatoid arthritis (10) Leukemia (10) Respiratory distress (10) Low levels of vitamin D (10) Behavioral abnormality (9) Mental deterioration (9) Chronic pain (9) Congestive heart failure (8) Myocarditis (8) Type I diabetes mellitus (8) Sepsis (8) Infertility (7) Abnormality of the liver (7) Lymphopenia (7) Inflammation of the large intestine (7) Pulmonary obstruction (7) Pulmonary insufficiency (7) Immunodeficiency (6) Systemic lupus erythematosus (6) Chronic pulmonary obstruction (6) 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    HP:0006775: Multiple myeloma

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (2)


    Name (Synonyms) Correlation
    drug3888 n/a - samples collected along routine care samples only Wiki 0.71
    drug1132 Electric pad for human external pain therapy Wiki 0.71

    Correlated MeSH Terms (6)


    Name (Synonyms) Correlation
    D009101 Multiple Myeloma NIH 1.00
    D054219 Neoplasms, Plasma Cell NIH 1.00
    D003141 Communicable Diseases NIH 0.05
    Name (Synonyms) Correlation
    D007239 Infection NIH 0.03
    D045169 Severe Acute Respiratory Syndrome NIH 0.03
    D018352 Coronavirus Infections NIH 0.02

    Correlated HPO Terms (0)


    Name (Synonyms) Correlation

    Clinical Trials

    Navigate: Correlations   HPO

    There are 2 clinical trials


    1 COVID-19 INFECTION IN MULTIPLE MYELOMA PATIENTS: AN EUROPEAN OBSERVATIONAL STUDY

    Collect in an observational study the outcomes of COVID19 infection in MM patients across Europe.

    NCT04492371
    Conditions
    1. Multiple Myeloma
    2. Covid19
    3. Corona Virus Infection
    MeSH:Infection Communicable Diseases Coronavirus Infections Severe Acute Respiratory Syndrome Multiple Myeloma Neoplasms, Plasma Cell
    HPO:Multiple myeloma

    Primary Outcomes

    Description: The duration of infection.

    Measure: Nature of COVID19

    Time: 1 years

    Description: Costs related to Covid in terms of health resource needs.

    Measure: Costs related to COVID-19

    Time: 1 years

    Description: Number of infection recovery for each systemic anti-cancer subgroup.

    Measure: Systemic anti-cancer therapy subgroup

    Time: 1 years

    Description: Evaluate if recurring haematological and chemistry values are related to infection onset, better or poorer outcome.

    Measure: Laboratory values collected at hospitalization

    Time: 1 years

    Description: Number of infection in each myeloma patient subgroups and evaluation of the number of recovery per subgroup.

    Measure: COVID-19 infection in myeloma patient subgroups

    Time: 1 years

    Description: Number of frail patients with COVID-19 infection and resolution of it.

    Measure: Incidence of COVID-19 infection in frail patients

    Time: 1 years

    Description: Number of infection and outcome per country.

    Measure: Infection outcome in different countries

    Time: 1 years
    2 Circulating Tumour Protein Quantification From Capillary Blood for Patient Selfsampling and Safe Remote Monitoring of Multiple Myeloma During COVID-19

    The coronavirus (COVID-19) pandemic has brought severe challenges for myeloma patients. Myeloma patients are considered ultra-high risk for COVID-19 and fall into the strictest group for shielding. When on treatment, but also during times of active surveillance, patients have to regularly and frequently leave shielding and visit the hospital for blood tests to monitor their disese. This is specifically for quantification of circulating tumour protein biomarker tests for paraprotein (PP) and/or serum free light chains (sFLCs) by specialised biochemistry units. This research aims to evaluate the potential use of an at-home patient administered technique to sample blood. The purpose of the blood sampling technique is to monitor your disease status. We want to test if it is possible to monitor a patient's disease status using this alternative blood collection method when compared to monitoring disease status using the traditional blood collection methods (venous blood sampling). The new VAMS method is not intended to be used interchangeably or will not replace the current method. This study is to evaluate an alternative sample type that may be used to improve the patient pathway, especially during these uncertain times.

    NCT04659252
    Conditions
    1. Multiple Myeloma
    Interventions
    1. Other: n/a - samples collected along routine care samples only
    MeSH:Multiple Myeloma Neoplasms, Plasma Cell
    HPO:Multiple myeloma

    Primary Outcomes

    Description: Validated FLC method for use with VAMS that conforms to ISO15189:2012 accreditation

    Measure: Validated FLC

    Time: 6 months

    HPO Nodes


    Reports

    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

    Drug Reports   MeSH Reports   HPO Reports  

    Interventions

    4,818 reports on interventions/drugs

    MeSH

    706 reports on MeSH terms

    HPO

    306 reports on HPO terms

    All Terms

    Alphabetical index of all Terms

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