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  • HP:0011123: Inflammatory abnormality of the skin
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    HP:0011123: Inflammatory abnormality of the skin

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (1)


    Name (Synonyms) Correlation
    drug3429 Treatment for COVID-19 Wiki 1.00

    Correlated MeSH Terms (1)


    Name (Synonyms) Correlation
    D003872 Dermatitis NIH 1.00

    Correlated HPO Terms (0)


    Name (Synonyms) Correlation

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 Re-opening of the Country and Dermal Consequences of Mandatory Intensified Handwash and Hand Disinfection Among a Danish Pediatric Population During the COVID19 Pandemic

    During the COVID-19 pandemic after reopening of the country, school, kindergarten and daycare, children have been obligated to do frequent handwash. The study group wished to investigate whether this has had implications on symptoms of dry, red, itchy or sore hands and hand eczema. The investigation was performed within the first and second week after reopening by questionnaires distributed to parents electronically via schools, kindergartens and daycare facilities electronic platforms.

    NCT04375410
    Conditions
    1. Hand Eczema
    2. Hand Dermatitis
    3. Covid19
    MeSH:Dermatitis
    HPO:Inflammatory abnormality of the skin

    Primary Outcomes

    Description: Dermal symptoms as a result of frequent hand wash and disinfection among children

    Measure: Dermal reaction to frequent hand wash and disinfection in children

    Time: 9 days

    HPO Nodes


    HP:0011123: Inflammatory abnormality of the skin
    Genes 508
    PSMB4 ALOXE3 ABCA12 NFE2L2 COL7A1 NFKB2 TREX1 CACNA1G DHCR7 CASP8 COL7A1 CD247 TRAF6 KRT16 PSENEN SPINK5 IFNG KIT ARVCF EGFR LAMA3 HLA-C JAK3 ZNF341 RREB1 LMBRD1 GJC2 NLRP3 HPGD GNA11 BTK BTNL2 PEPD PIK3CD TGM1 HLA-DPA1 RAC1 KRT10 GJB6 ZAP70 H6PD KRT1 MRTFA ABCA12 CYP4F22 TRAF3IP2 WAS NLRP3 GJB2 CYBC1 TGM1 RAG1 TARS1 SMARCA2 TTC7A CLEC7A HIRA FLI1 GP1BB MORC2 BRAF TGM1 FERMT3 SEC24C EXTL3 MCCC2 IL36RN PAH PIGA HLCS CYBA HLA-DPB1 NLRP12 SIK3 HPGD FOXP3 SLC30A2 ABCA12 AP3B1 LIPN CD28 CASP10 CARD14 TCF3 LMBRD1 IL17RA NOD2 LACC1 SHOC2 IL10RA WNT4 IL7 TGM5 CTLA4 ADAMTS3 PAPSS2 DOCK8 HLA-B KRT14 PCCA LIG4 BLM PLA2G7 RNU4ATAC KNSTRN KDF1 GJC2 KIT SMARCAD1 ZNF750 TNFRSF1B PTPN22 ERCC2 IL7R KRT10 FECH CHST14 CIITA KIT STX11 MEFV LIG4 DNAJC21 IL2RA ALOXE3 ENPP1 ACADVL IKBKG PRTN3 SP110 TKT RFX5 EPB42 MEFV NOD2 NOD2 GJA1 FCGR2B RAG1 MVK CTLA4 TREX1 ZAP70 ECM1 MSMO1 SMARCC2 ALOX12B IFIH1 CCBE1 TFRC NFKB1 GJB4 TAF1 NLRP3 USP8 BTD DOCK8 LACC1 TCIRG1 CDK10 STING1 FLI1 ESR1 EDA STAT1 AIRE SRP54 MBTPS2 GATA3 MYD88 RMRP HLA-DRB1 GPR101 C4A DNAJC21 AP1B1 BTK PDGFRA CYP4F22 HPGD RAC1 MEFV CCBE1 RBCK1 ADA RNASEH2B PRMT7 PSMB9 CTSC TNFAIP3 PRF1 SLC4A1 STAT1 MBTPS2 MIF TGM1 SPP1 MYD88 LBR NCF2 IL17F FOXP3 TMC6 CSTA FGFR2 IRF2BP2 CTLA4 SDHA RBP4 RAG1 SMARCA2 KANSL1 SBDS CARD14 RFXAP GJB2 IL6ST PTPN22 ACP5 XIAP ESR1 TTC7A UROS RNASEH2A IL2RG SPTB POLR3A BTK KRT5 DNASE1L3 KRT1 FLT4 TP63 LRRC8A IL12A-AS1 SCNN1B LPIN2 C5 EPG5 LBR MS4A2 ANK1 CTLA4 IL12A GFI1 KANSL1 TP63 NIPAL4 IL17RC POMP MYSM1 SLCO2A1 DSE SDHB TMC8 LYZ NLRP3 CHD7 DSG1 NSUN2 FERMT1 NCF4 B2M SRP54 HLCS WIPF1 LYST MEIS2 SLC39A4 GATA1 EBP POLE MNX1 CDH23 ITGB4 SLC29A3 VEGFC TRPM4 TNFRSF1A DDX41 RAG2 JAK1 PGM3 SULT2B1 JMJD1C SDR9C7 MSN NIPAL4 HYOU1 TBX1 MYSM1 IL10 TBX1 GINS1 NCF4 IL4R COX4I2 RFXANK WIPF1 KRT1 NCF2 TNFRSF1B MPLKIP FOXP1 PSTPIP1 AGA LAMC2 RAG2 FECH RNASEH2C IL17F NCSTN DCLRE1C WAS PEPD IL6 NCF1 CD3D ERCC3 ERCC4 PSMB8 IL7R CTSC STAT3 SH3PXD2B STAT4 SPTA1 IL17RA SAMHD1 IGLL1 PSEN1 COL7A1 SLC6A19 CERS3 NSUN2 TRAF3IP2 TBX1 RNF113A IGHM CD79A PIK3R1 PIK3CA KRT10 FAM111B KDSR SCNN1G ADAM17 CD79B LRRC32 KRT17 BCL11B IVNS1ABP HLA-DRB1 CYBB KRT5 ERCC2 CD3E PTPRC IL23R SRD5A3 TEK FLG SPINK5 CYBA CARD11 CD3G LSS TREX1 CYBB IL10RB LPIN2 STAT3 CLEC7A ITGA6 PGM3 MBL2 STAT3 RTTN SREBF1 HDAC4 CARD9 RFX5 CHST14 DCLRE1C TLR4 MPDU1 NCF1 CYBC1 FGA SUOX IL2RG MEFV GJB3 EGFR OTULIN WAS CASR WNT4 CD247 CFI SAMHD1 UFD1 NSMCE3 RFXAP TREX1 CARMIL2 ABCC6 TNFRSF1A MEFV SHANK3 STAT4 IL6R LAMB3 GTF2H5 APOA1 GJB2 IL1RN IRAK1 KANSL1 GTF2H5 IFIH1 FAT4 RIPK1 RNASEH2C CIITA CCR1 KIF11 ALOX12B UBAC2 UBE2A RNU4ATAC AIP XYLT1 PNPLA1 RBM8A FAS NLRC4 HLA-DQB1 NEK9 HSPA9 PCCB MTHFD1 CTLA4 PSTPIP1 KRT1 EDARADD TGFB1 NR3C1 ERAP1 WDR1 CD28 PRKACA ADA2 CIB1 LYST TBCK ADAR POR ELANE STAT5B MBTPS2 PNPLA1 RFXANK EFL1 KLRC4 FOXC2 DNASE1 MMP1 KRT9 RRAS2 HLA-DRB1 AIRE LIG4 NFKB2 AK2 DCLRE1C NAXD SCNN1A LHCGR HSD3B2 LRBA ELANE GTF2E2 SH3PXD2B COMT EDAR FOXN1 BLNK IL2RG IL7R ERCC3 NIPAL4 ERCC2 RAG2 AP1S3 SDHC ADA FCGR2A AUTS2 PAH ERCC5 CTSB BTNL2 ADAM17 KDF1 HLA-B BTD MVK
    Protein Mutations 4
    G2545R H2507Q T454A V66M
    SNP 1
    rs6265

    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    HPO Nodes


    HP:0011123: Inflammatory abnormality of the skin
    Genes 508
    PSMB4 ALOXE3 ABCA12 NFE2L2 COL7A1 NFKB2 TREX1 CACNA1G DHCR7 CASP8 COL7A1 CD247 TRAF6 KRT16 PSENEN SPINK5 IFNG KIT ARVCF EGFR LAMA3 HLA-C JAK3 ZNF341 RREB1 LMBRD1 GJC2 NLRP3 HPGD GNA11 BTK BTNL2 PEPD PIK3CD TGM1 HLA-DPA1 RAC1 KRT10 GJB6 ZAP70 H6PD KRT1 MRTFA ABCA12 CYP4F22 TRAF3IP2 WAS NLRP3 GJB2 CYBC1 TGM1 RAG1 TARS1 SMARCA2 TTC7A CLEC7A HIRA FLI1 GP1BB MORC2 BRAF TGM1 FERMT3 SEC24C EXTL3 MCCC2 IL36RN PAH PIGA HLCS CYBA HLA-DPB1 NLRP12 SIK3 HPGD FOXP3 SLC30A2 ABCA12 AP3B1 LIPN CD28 CASP10 CARD14 TCF3 LMBRD1 IL17RA NOD2 LACC1 SHOC2 IL10RA WNT4 IL7 TGM5 CTLA4 ADAMTS3 PAPSS2 DOCK8 HLA-B KRT14 PCCA LIG4 BLM PLA2G7 RNU4ATAC KNSTRN KDF1 GJC2 KIT SMARCAD1 ZNF750 TNFRSF1B PTPN22 ERCC2 IL7R KRT10 FECH CHST14 CIITA KIT STX11 MEFV LIG4 DNAJC21 IL2RA ALOXE3 ENPP1 ACADVL IKBKG PRTN3 SP110 TKT RFX5 EPB42 MEFV NOD2 NOD2 GJA1 FCGR2B RAG1 MVK CTLA4 TREX1 ZAP70 ECM1 MSMO1 SMARCC2 ALOX12B IFIH1 CCBE1 TFRC NFKB1 GJB4 TAF1 NLRP3 USP8 BTD DOCK8 LACC1 TCIRG1 CDK10 STING1 FLI1 ESR1 EDA STAT1 AIRE SRP54 MBTPS2 GATA3 MYD88 RMRP HLA-DRB1 GPR101 C4A DNAJC21 AP1B1 BTK PDGFRA CYP4F22 HPGD RAC1 MEFV CCBE1 RBCK1 ADA RNASEH2B PRMT7 PSMB9 CTSC TNFAIP3 PRF1 SLC4A1 STAT1 MBTPS2 MIF TGM1 SPP1 MYD88 LBR NCF2 IL17F FOXP3 TMC6 CSTA FGFR2 IRF2BP2 CTLA4 SDHA RBP4 RAG1 SMARCA2 KANSL1 SBDS CARD14 RFXAP GJB2 IL6ST PTPN22 ACP5 XIAP ESR1 TTC7A UROS RNASEH2A IL2RG SPTB POLR3A BTK KRT5 DNASE1L3 KRT1 FLT4 TP63 LRRC8A IL12A-AS1 SCNN1B LPIN2 C5 EPG5 LBR MS4A2 ANK1 CTLA4 IL12A GFI1 KANSL1 TP63 NIPAL4 IL17RC POMP MYSM1 SLCO2A1 DSE SDHB TMC8 LYZ NLRP3 CHD7 DSG1 NSUN2 FERMT1 NCF4 B2M SRP54 HLCS WIPF1 LYST MEIS2 SLC39A4 GATA1 EBP POLE MNX1 CDH23 ITGB4 SLC29A3 VEGFC TRPM4 TNFRSF1A DDX41 RAG2 JAK1 PGM3 SULT2B1 JMJD1C SDR9C7 MSN NIPAL4 HYOU1 TBX1 MYSM1 IL10 TBX1 GINS1 NCF4 IL4R COX4I2 RFXANK WIPF1 KRT1 NCF2 TNFRSF1B MPLKIP FOXP1 PSTPIP1 AGA LAMC2 RAG2 FECH RNASEH2C IL17F NCSTN DCLRE1C WAS PEPD IL6 NCF1 CD3D ERCC3 ERCC4 PSMB8 IL7R CTSC STAT3 SH3PXD2B STAT4 SPTA1 IL17RA SAMHD1 IGLL1 PSEN1 COL7A1 SLC6A19 CERS3 NSUN2 TRAF3IP2 TBX1 RNF113A IGHM CD79A PIK3R1 PIK3CA KRT10 FAM111B KDSR SCNN1G ADAM17 CD79B LRRC32 KRT17 BCL11B IVNS1ABP HLA-DRB1 CYBB KRT5 ERCC2 CD3E PTPRC IL23R SRD5A3 TEK FLG SPINK5 CYBA CARD11 CD3G LSS TREX1 CYBB IL10RB LPIN2 STAT3 CLEC7A ITGA6 PGM3 MBL2 STAT3 RTTN SREBF1 HDAC4 CARD9 RFX5 CHST14 DCLRE1C TLR4 MPDU1 NCF1 CYBC1 FGA SUOX IL2RG MEFV GJB3 EGFR OTULIN WAS CASR WNT4 CD247 CFI SAMHD1 UFD1 NSMCE3 RFXAP TREX1 CARMIL2 ABCC6 TNFRSF1A MEFV SHANK3 STAT4 IL6R LAMB3 GTF2H5 APOA1 GJB2 IL1RN IRAK1 KANSL1 GTF2H5 IFIH1 FAT4 RIPK1 RNASEH2C CIITA CCR1 KIF11 ALOX12B UBAC2 UBE2A RNU4ATAC AIP XYLT1 PNPLA1 RBM8A FAS NLRC4 HLA-DQB1 NEK9 HSPA9 PCCB MTHFD1 CTLA4 PSTPIP1 KRT1 EDARADD TGFB1 NR3C1 ERAP1 WDR1 CD28 PRKACA ADA2 CIB1 LYST TBCK ADAR POR ELANE STAT5B MBTPS2 PNPLA1 RFXANK EFL1 KLRC4 FOXC2 DNASE1 MMP1 KRT9 RRAS2 HLA-DRB1 AIRE LIG4 NFKB2 AK2 DCLRE1C NAXD SCNN1A LHCGR HSD3B2 LRBA ELANE GTF2E2 SH3PXD2B COMT EDAR FOXN1 BLNK IL2RG IL7R ERCC3 NIPAL4 ERCC2 RAG2 AP1S3 SDHC ADA FCGR2A AUTS2 PAH ERCC5 CTSB BTNL2 ADAM17 KDF1 HLA-B BTD MVK
    Protein Mutations 4
    G2545R H2507Q T454A V66M
    SNP 1
    rs6265

    Reports

    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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