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  • HP:0030151: Cholangitis
  • Pneumonia (361) Abnormality of the cardiovascular system (36) Respiratory tract infection (36) Neoplasm (29) Hypoxemia (28) Diabetes mellitus (25) Depressivity (24) Thromboembolism (23) Acute kidney injury (22) Abnormal lung morphology (21) Anosmia (19) Hypertension (18) Abnormality of coagulation (15) Pulmonary embolism (15) Pulmonary fibrosis (15) Stroke (14) Arthritis (14) Interstitial pneumonitis (14) Myocardial infarction (12) Type II diabetes mellitus (12) Deep venous thrombosis (11) Rheumatoid arthritis (10) Leukemia (10) Respiratory distress (10) Low levels of vitamin D (10) Behavioral abnormality (9) Mental deterioration (9) Chronic pain (9) Congestive heart failure (8) Myocarditis (8) Type I diabetes mellitus (8) Sepsis (8) Infertility (7) Abnormality of the liver (7) Lymphopenia (7) Inflammation of the large intestine (7) Pulmonary obstruction (7) Pulmonary insufficiency (7) Immunodeficiency (6) Systemic lupus erythematosus (6) Chronic pulmonary obstruction (6) Abnormality of the gastrointestinal tract (6) Neoplasm of the lung (6) Encephalopathy (5) Obesity (5) Lymphoma (5) Autoimmunity (5) Breast carcinoma (5) Disseminated intravascular coagulation (5) Fatigue (5) Abnormality of the kidney (4) Coronary artery atherosclerosis (4) Cardiac arrest (4) Headache (4) Colon cancer (4) Arrhythmia (4) Carcinoma (4) Hypercoagulability (4) Autistic behavior (3) Seizure (3) Cardiomyopathy (3) Dysphagia (3) Migraine (3) Pulmonary arterial hypertension (3) Asthma (3) Bronchiectasis (3) Neoplasm of the pancreas (3) Psoriasiform dermatitis (3) Attention deficit hyperactivity disorder (3) Cutaneous melanoma (3) Neoplasm of head and neck (3) Pulmonary edema (3) Insomnia (3) Neoplasm of the large intestine (3) Renal insufficiency (2) Hypogeusia (2) Hearing impairment (2) Abnormality of the eye (2) Visual impairment (2) Conjunctivitis (2) Psychosis (2) Autism (2) Dementia (2) Abnormality of the endocrine system (2) Abnormality of the thyroid gland (2) Jaundice 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    HP:0030151: Cholangitis

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO

    Correlated Drug Terms (6)

    Name (Synonyms) Correlation
    drug1353 Graded exercise test Wiki 0.71
    drug780 Cloth Face Mask Wiki 0.71
    drug1160 Endoscopic management according to standard of care Wiki 0.71
    Name (Synonyms) Correlation
    drug781 Clungene rapid test cassette Wiki 0.71
    drug3654 [18F]FP-R01-MG-F2 Wiki 0.71
    drug2065 N-95 Respirator Wiki 0.71

    Correlated MeSH Terms (11)

    Name (Synonyms) Correlation
    D002761 Cholangitis NIH 1.00
    D015209 Cholangitis, Sclerosing NIH 0.71
    D008105 Liver Cirrhosis, Biliary NIH 0.71
    Name (Synonyms) Correlation
    D041781 Jaundice, Obstructive NIH 0.71
    D007565 Jaundice, NIH 0.50
    D018281 Cholangiocarcinoma NIH 0.50
    D054990 Idiopathic Pulmonary Fibrosis NIH 0.50
    D010190 Pancreatic Neoplasms NIH 0.41
    D005355 Fibrosis NIH 0.20
    D011658 Pulmonary Fibrosis NIH 0.18
    D011014 Pneumonia NIH 0.04

    Correlated HPO Terms (6)

    Name (Synonyms) Correlation
    HP:0002613 Biliary cirrhosis HPO 0.71
    HP:0030153 Cholangiocarcinoma HPO 0.50
    HP:0000952 Jaundice HPO 0.50
    Name (Synonyms) Correlation
    HP:0002894 Neoplasm of the pancreas HPO 0.41
    HP:0002206 Pulmonary fibrosis HPO 0.18
    HP:0002090 Pneumonia HPO 0.04

    Clinical Trials

    Navigate: Correlations   HPO

    There are 2 clinical trials

    1 Detection of Integrin avb6 in Idiopathic Pulmonary Fibrosis, Primary Sclerosing Cholangitis, and Coronavirus Disease 2019 With [18F]FP-R01-MG-F2 With PET/CT

    Detection of Integrin avb6 in Idiopathic Pulmonary Fibrosis, Primary Sclerosing Cholangitis, and Coronavirus Disease 2019 with [18F]FP-R01-MG-F2 with PET/CT

    1. Idiopathic Pulmonary Fibrosis
    2. Primary Sclerosing Cholangitis
    3. Covid19 Pneumonia
    1. Drug: [18F]FP-R01-MG-F2
    MeSH:Cholangitis Cholangitis, Sclerosing Pneumonia Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis Fibrosis
    HPO:Cholangitis Pneumonia Pulmonary fibrosis

    Primary Outcomes

    Description: The SUVmax in a lung or liver with known IPF, COVID19 pneumonia, or PSC respectively will be compared to the SUVmax in a known healthy lung/liver. It is expected that the SUV max, which is a measurement of the maximum value of radiopharmaceutical uptake within the region of interest (ROI) in IPF, COVID19 pneumonia, and PSC will be higher than the SUV max in the healthy lung/liver.

    Measure: SUV max comparison : IPF versus Healthy Lung, PSC versus Healthy Liver, COVID19 versus Healthy Lung

    Time: an estimated average of 2 hours

    Secondary Outcomes

    Description: Blood samples for blood time-activity measurements taken at 1, 3, 5, 10, 30, and 60 minutes after tracer injection for tracer kinetic analysis. Tracer kinetic analysis shows radiopharmaceutical distribution from the blood to the tissues over time.

    Measure: Time Activity Measurements

    Time: an estimated average of 1 hours

    Description: EKG data, vital signs and laboratory data collected before IV injection of [18F]FP-R01-MG-F2 and after completion of the scan will allow the investigators to evaluate the safety and tolerability of the radiopharmaceutical. This will be measured as the number of patients who successfully completed the study.

    Measure: Incidence of Study Completion (Safety and Tolerability)

    Time: an estimated average of 2 hours
    2 The Status of Advanced Endoscopy in the Era of COVID-19: a Multicenter Study

    In this study, investigators aim to explore the status of advanced endoscopy in different endoscopy units all over the world.

    1. Cholangitis, Secondary Biliary
    2. Cholangiocarcinoma
    3. Obstructive Jaundice
    4. Pancreas Cancer
    5. COVID-19
    6. SARS-CoV-2
    1. Other: Endoscopic management according to standard of care
    MeSH:Cholangiocarcinoma Pancreatic Neoplasms Cholangitis Liver Cirrhosis, Biliary Jaundice Jaundice, Obstructive
    HPO:Biliary cirrhosis Cholangiocarcinoma Cholangitis Jaundice Neoplasm of the pancreas

    Primary Outcomes

    Description: Investigators will report the baseline demographic data (age, gender, nationality) of all patients.

    Measure: Age, gender, nationality

    Time: 3 months

    Description: Investigators will report the baseline data clinical data (indication for procedure, status of SARS-CoV-2 infection) of all patients.

    Measure: Indication for procedure, status of SARS-CoV-2 infection

    Time: 3 months

    Description: Investigators will report the baseline laboratory data (complete blood count and liver functions tests) of all patients.

    Measure: Complete blood count and liver functions tests

    Time: 3 months

    Description: Investigators will report the procedure related complications.

    Measure: procedure related complications

    Time: 3 months

    Secondary Outcomes

    Description: Investigators will report wether the precautions lead to increase timing of the procedure

    Measure: Effect of COVID-19 precautions on procedure time

    Time: 3 months

    Description: Investigators will report wether the precautions affected staff number (increased or decreased)

    Measure: Effect of COVID-19 precautions on staff number

    Time: 3 months

    HPO Nodes


    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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    706 reports on MeSH terms


    306 reports on HPO terms

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