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  • HP:0000224: Hypogeusia
  • Pneumonia (361) Abnormality of the cardiovascular system (36) Respiratory tract infection (36) Neoplasm (29) Hypoxemia (28) Diabetes mellitus (25) Depressivity (24) Thromboembolism (23) Acute kidney injury (22) Abnormal lung morphology (21) Anosmia (19) Hypertension (18) Abnormality of coagulation (15) Pulmonary embolism (15) Pulmonary fibrosis (15) Stroke (14) Arthritis (14) Interstitial pneumonitis (14) Myocardial infarction (12) Type II diabetes mellitus (12) Deep venous thrombosis (11) Rheumatoid arthritis (10) Leukemia (10) Respiratory distress (10) Low levels of vitamin D (10) Behavioral abnormality (9) Mental deterioration (9) Chronic pain (9) Congestive heart failure (8) Myocarditis (8) Type I diabetes mellitus (8) Sepsis (8) Infertility (7) Abnormality of the liver (7) Lymphopenia (7) Inflammation of the large intestine (7) Pulmonary obstruction (7) Pulmonary insufficiency (7) Immunodeficiency (6) Systemic lupus erythematosus (6) Chronic pulmonary obstruction (6) 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    HP:0000224: Hypogeusia

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (5)


    Name (Synonyms) Correlation
    drug1764 Late dexamethazone Wiki 0.71
    drug2080 NHANES smell and taste tests Wiki 0.71
    drug358 BCG Vaccine Wiki 0.71
    Name (Synonyms) Correlation
    drug1115 Early-Dexamethasone Wiki 0.50
    drug2448 Placebo Wiki 0.07

    Correlated MeSH Terms (5)


    Name (Synonyms) Correlation
    D000370 Ageusia NIH 1.00
    D000857 Olfaction Disorders NIH 0.32
    D014777 Virus Diseases NIH 0.08
    Name (Synonyms) Correlation
    D045169 Severe Acute Respiratory Syndrome NIH 0.03
    D018352 Coronavirus Infections NIH 0.02

    Correlated HPO Terms (1)


    Name (Synonyms) Correlation
    HP:0000458 Anosmia HPO 0.32

    Clinical Trials

    Navigate: Correlations   HPO

    There are 2 clinical trials


    1 Investigating Anosmia and Ageusia in COVID-19 Adult Patients in Saudi Arabia

    COVID-19 has adversely affected the healthcare system across the world. The world was not prepared for global outbreak of infectious diseases. The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is enabling researchers worldwide to acquire a large amount of clinical data regarding coronavirus disease (COVID-19). The COVID-19 infection severely affects the respiratory system in the critical cases and results in mortalities. The affected people experience a dry cough, fever, breathing problems, diarrhea, muscle pain, and sore throat. Besides that, some of the evidence from Italy, South Korea, China, and Spain suggest that the COVID-19 cases also lose their senses of smell and taste resulting in alterations in those patients. The objective of this proposed study is to determine whether COVID-19 cases have Olfactory and gustatory dysfunctions as a hallmark indicator and can be used as diagnostic tools for the isolation of suspected people. Investigators are presenting a prospective proportional case-control study that is conducted to investigate the COVID-19 cases with anosmia and /or Ageusia in a university hospital in Riyadh, Saudi Arabia. The sample size of this case series would be 250 cases of suspected COVID-19 patients. The cases included in the study are analyzed prospectively to determine if the cases had a history of anosmia and /or Ageusia, and then tested for the alteration of these senses through a panel of standardized odors/taste strips. That is looked at statistically allowing us to confirm the proposed effectiveness of these tests as a diagnostic tool.

    NCT04388618
    Conditions
    1. Anosmia
    2. Ageusia
    3. Covid19
    4. Corona Virus Infection
    Interventions
    1. Other: NHANES smell and taste tests
    MeSH:Virus Diseases Coronavirus Infections Severe Acute Respiratory Syndrome Olfaction Disorders Ageusia
    HPO:Anosmia Hypogeusia

    Primary Outcomes

    Description: to how extent alteration of smell and taste senses is related to covid19 status

    Measure: correlation of anosmia and ageusia to covid19 positive patients

    Time: from 1/06/2020 to 31/12/2020

    Secondary Outcomes

    Description: to determine the range of sense affection ranging from total loss to mild form

    Measure: objective assessment of severity of smell and taste senses alterations in covid19 patients

    Time: from 1/06/2020 to 31/12/2020
    2 Time to Recover of Anosmia and / or Ageusia and Early Corticosteroid Use

    Time to recover of Anosmia and / or ageusia and early corticosteroid use

    NCT04528329
    Conditions
    1. Covid19
    2. Anosmia
    Interventions
    1. Drug: Early-Dexamethasone
    2. Drug: Late dexamethazone
    MeSH:Olfaction Disorders Ageusia
    HPO:Anosmia Hypogeusia

    Primary Outcomes

    Description: Time to recovery from anosmia and / or agusia

    Measure: Time to recovery

    Time: one to 6 weeks

    HPO Nodes


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    HPO Nodes


    Reports

    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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