Developed by Shray Alag, The Harker School
Sections: Correlations,
Clinical Trials, and HPO
Navigate: Clinical Trials and HPO
Name (Synonyms) | Correlation | |
---|---|---|
D051346 | Mobility Limitation NIH | 1.00 |
D000073496 | Frailty NIH | 0.41 |
D045169 | Severe Acute Respiratory Syndrome NIH | 0.04 |
Name (Synonyms) | Correlation |
---|
Navigate: Correlations HPO
There is one clinical trial.
Older adults and those with chronic underlying health conditions are the most susceptible to COVID-19 and its complications. Although there has been a rapid response to studying the effects of COVID-19 in the acute stages, little is known about recovery over the longer-term. Older adults who survive the diseases are at risk of developing persistent mobility limitations due to extensive bed rest during hospitalization. For older patients and those with underlying frailty recovering from COVID-19, this could rapidly lead to significant physical deconditioning and rapid declines in mobility. Understanding the trajectory of functional recovery of older hospitalised patients with COVID-19 in the short- and long-term is critical to improving patient outcomes and informing health and rehabilitative interventions for survivors.
Description: The AM-PAC is an activity limitation instrument based on the International Classification of Functioning, Disability and Health (ICF) that assesses 3 functional domains: basic mobility, daily activities and applied cognition.
Measure: Change in Activity Measure for Post Acute Care (AM-PAC) Basic Mobility Inpatient Version Time: Admission to hospital ward (0-14 days post ward admission) and discharge from hospital (0-14 days post discharge or up to 6 months, whichever comes first)Description: The AM-PAC is an activity limitation instrument based on the International Classification of Functioning, Disability and Health (ICF) that assesses 3 functional domains: basic mobility, daily activities and applied cognition.
Measure: Change in Activity Measure for Post Acute Care (AM-PAC) Basic Mobility Outpatient Version Time: Admission to hospital ward (0-14 days post ward admission, to capture pre-morbid function), and at 3,6,9 and 12-months post hospital dischargeDescription: The AM-PAC is an activity limitation instrument based on the International Classification of Functioning, Disability and Health (ICF) that assesses 3 functional domains: basic mobility, daily activities and applied cognition.
Measure: Change in Activity Measure for Post Acute Care (AM-PAC) Applied Cognitive Inpatient Version Time: Admission to hospital ward (0-14 days post ward admission) and discharge from hospital (0-14 days post discharge or up to 6 months, whichever comes first)Description: The AM-PAC is an activity limitation instrument based on the International Classification of Functioning, Disability and Health (ICF) that assesses 3 functional domains: basic mobility, daily activities and applied cognition.
Measure: Change in Activity Measure for Post Acute Care (AM-PAC) Daily Activity Time: 3,6,9 and 12-months post hospital dischargeDescription: The SPPB combines the results of gait speed over 3 meters, the 5-repetition chair-stand, and a progressive balance test to assess lower extremity function.
Measure: Change in Short Physical Performance Battery (SPPB) Time: 3,6,9 and 12-months post hospital dischargeDescription: The CFS is an interview-based scale wherein the assessor may ask the patient questions about things such as their independence or physical abilities to determine where the patient falls along the 9-point scale, from 1 (Very Fit) to 9 (Terminally Ill).
Measure: Change in Clinical Frailty Scale (CFS) for participants over 60 years of age Time: Admission to hospital ward (0-14 days post ward admission, to capture pre-morbid function ), and at 3,6,9 and 12-months post hospital dischargeDescription: The Forced Expiratory Volume in 1 Second parameter measures the volume of air that was exhaled into the mouthpiece in the first second after a full inhalation as measured by spirometry.
Measure: Change in Forced Expiratory Volume (FEV1) Time: 3,6,9 and 12-months post hospital dischargeDescription: The amount of air that can be forcibly exhaled from your lungs after taking the deepest breath possible, as measured by spirometry. FVC is the total amount of air exhaled during the FEV test.
Measure: Change in Forced Vital Capacity (FVC) Time: 3,6,9 and 12-months post hospital dischargeDescription: The FEV1/FVC Ratio (FEV1%) parameter is calculated by dividing the measured FEV1 value by the measured FVC value.
Measure: Change in Forced Expiratory Volume Percentage (FEV1%) Time: 3,6,9 and 12-months post hospital dischargeDescription: The BDI rates the severity of dyspnea at a single point in time (baseline) based on a 24-item interviewer administered rating scale.
Measure: Baseline Dyspnea Index (BDI) Time: 3 months post hospital dischargeDescription: Measures changes in dyspnea severity from the baseline as established by the BDI.
Measure: Change in Transition Dyspnea Index (TDI) Time: 6,9 and 12-months post hospital dischargeDescription: The PHQ-9 is a self-rating instrument for depression based on nine questions that the patient responds to by indicating how much they have been bothered by these symptoms over the last two weeks.
Measure: Change in Patient Health Questionnaire - 9 (PHQ-9) Time: 3,6,9 and 12-months post hospital dischargeDescription: The FIM assesses the functional status of a person based on the level of assistance the person requires.
Measure: Change in Functional Independence Measure (FIM) Time: 3 and 6 months post hospital dischargeDescription: The IES-R is a 22-item self-report measure that asks questions about subjective distress caused by traumatic events. Each item is rated on a 5-point scale, from 0 ("not at all") to 4 ("extremely").
Measure: Change in Impact of Event Scale - Revised (IES-R) Time: 3,6,9 and 12-months post hospital dischargeDescription: The EQ-5D-5L is a generic and well-established instrument for describing health status or disease-specific outcome measures. It defines health in terms of five dimensions: Mobility, Self- Care, Usual Activities, Pain/Discomfort, and Anxiety/ Depression. The response options are of five levels, from no, slight, moderate, severe, to extreme problems
Measure: Change in Health status (EQ-5D-5L) Time: 3,6,9 and 12-months post hospital dischargeAlphabetical listing of all HPO terms. Navigate: Correlations Clinical Trials
Data processed on December 13, 2020.
An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.
Drug Reports MeSH Reports HPO Reports