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    HP:0000952: Jaundice

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (4)


    Name (Synonyms) Correlation
    drug4332 Telesimulation Wiki 0.71
    drug1498 Endoscopic management according to standard of care Wiki 0.71
    drug1222 D-beta-hydroxybutyrate-(R)-1,3 butanediol monoester Wiki 0.71
    Name (Synonyms) Correlation
    drug3195 Placebo Wiki 0.03

    Correlated MeSH Terms (6)


    Name (Synonyms) Correlation
    D007565 Jaundice, NIH 1.00
    D008105 Liver Cirrhosis, Biliary NIH 0.71
    D041781 Jaundice, Obstructive NIH 0.71
    Name (Synonyms) Correlation
    D018281 Cholangiocarcinoma NIH 0.71
    D002761 Cholangitis NIH 0.50
    D010190 Pancreatic Neoplasms NIH 0.32

    Correlated HPO Terms (4)


    Name (Synonyms) Correlation
    HP:0030153 Cholangiocarcinoma HPO 0.71
    HP:0002613 Biliary cirrhosis HPO 0.71
    HP:0030151 Cholangitis HPO 0.50
    Name (Synonyms) Correlation
    HP:0002894 Neoplasm of the pancreas HPO 0.32

    Clinical Trials

    Navigate: Correlations   HPO

    There are 2 clinical trials


    1 The Status of Advanced Endoscopy in the Era of COVID-19: a Multicenter Study

    In this study, investigators aim to explore the status of advanced endoscopy in different endoscopy units all over the world.

    NCT04385147
    Conditions
    1. Cholangitis, Secondary Biliary
    2. Cholangiocarcinoma
    3. Obstructive Jaundice
    4. Pancreas Cancer
    5. COVID-19
    6. SARS-CoV-2
    Interventions
    1. Other: Endoscopic management according to standard of care
    MeSH:Cholangiocarcinoma Pancreatic Neoplasms Cholangitis Liver Cirrhosis, Biliary Jaundice Jaundice, Obstructive
    HPO:Biliary cirrhosis Cholangiocarcinoma Cholangitis Jaundice Neoplasm of the pancreas

    Primary Outcomes

    Description: Investigators will report the baseline demographic data (age, gender, nationality) of all patients.

    Measure: Age, gender, nationality

    Time: 3 months

    Description: Investigators will report the baseline data clinical data (indication for procedure, status of SARS-CoV-2 infection) of all patients.

    Measure: Indication for procedure, status of SARS-CoV-2 infection

    Time: 3 months

    Description: Investigators will report the baseline laboratory data (complete blood count and liver functions tests) of all patients.

    Measure: Complete blood count and liver functions tests

    Time: 3 months

    Description: Investigators will report the procedure related complications.

    Measure: procedure related complications

    Time: 3 months

    Secondary Outcomes

    Description: Investigators will report wether the precautions lead to increase timing of the procedure

    Measure: Effect of COVID-19 precautions on procedure time

    Time: 3 months

    Description: Investigators will report wether the precautions affected staff number (increased or decreased)

    Measure: Effect of COVID-19 precautions on staff number

    Time: 3 months
    2 Breastfeeding Education in the Time of COVID-19. Hybrid Telesimulation With Standardized Patients for Pediatric and Family Medicine Trainees, a Randomized Trial

    This project will establish that pediatric and family medicine residents who complete a hybrid breastfeeding medicine curriculum that includes an asynchronous unfolding case scenario along with telesimulation with a standardized patient (SP) will provide timely, skilled lactation support more frequently than residents randomized to an asynchronous unfolding case scenario followed by videoconference group discussion regarding care for the breastfeeding dyad.

    NCT04519216
    Conditions
    1. Breastfeeding
    2. Breastfeeding, Exclusive
    3. Breastfeeding Jaundice
    4. Educational Problems
    Interventions
    1. Behavioral: Telesimulation
    MeSH:Jaundice
    HPO:Jaundice

    Primary Outcomes

    Description: Breastfeeding medicine practice patterns of physician residents will be assessed at enrollment and following the intervention/control. Physician resident participants will complete a survey querying the number of times they have counseled patients about breastfeeding, the number of breast examinations performed, the number of witnessed breastfeeding sessions, and any experience with counseling about manual expression of breast milk.

    Measure: Change in practice patterns

    Time: at enrollment, 2 weeks and 3 months following intervention

    Secondary Outcomes

    Description: Physician residents (participants) will fill out a survey about their breastfeeding counseling self efficacy prior to and after the intervention.

    Measure: Self efficacy

    Time: at enrollment, 2 weeks and 3 months following intervention

    Description: Physician residents (participants) will fill out a survey about their satisfaction with the breast feeding medicine curriculum after the educational intervention.

    Measure: Satisfaction with simulation

    Time: Immediately following the educational intervention

    HPO Nodes


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


    HPO Nodes


    Reports

    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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