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  • HP:0004418: Thrombophlebitis
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    HP:0004418: Thrombophlebitis

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (0)


    Name (Synonyms) Correlation

    Correlated MeSH Terms (3)


    Name (Synonyms) Correlation
    D013924 Thrombophlebitis NIH 1.00
    D020246 Venous Thrombosis NIH 0.29
    D013927 Thrombosis NIH 0.19

    Correlated HPO Terms (1)


    Name (Synonyms) Correlation
    HP:0002625 Deep venous thrombosis HPO 0.29

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 COVID-19 and Deep Venous Thrombosis: a Cross-sectional Study

    The aim of this study is to investigate the prevalence and possible risk factors of the occurrence of a DVT in 12 intubated and mechanically ventilated COVID-19 patients admitted to the ICU at a single time point (29/03/2020).

    NCT04338932
    Conditions
    1. COVID-19
    2. Deep Vein Thrombosis (DVT)/Thrombophlebitis
    MeSH:Thrombosis Venous Thrombosis Thrombophlebitis
    HPO:Deep venous thrombosis Thrombophlebitis Venous thrombosis

    Primary Outcomes

    Description: to investigate the prevalence of a DVT in patients at the ICU.

    Measure: the prevalence of a DVT in patients at the ICU.

    Time: 1 day at ICU

    Secondary Outcomes

    Description: evaluate pO2 and pCO2 (mmHg) in patients with and without a DVT

    Measure: Oxygen partial pressure and Carbon dioxide partial pressure levels in the blood

    Time: 1 day at ICU

    Description: evaluate Potassium, Sodium, Calcium, Bicarbonate, Base excess, Lactate levels (mmol/l) in patients with and without a DVT

    Measure: Potassium, Sodium, Calcium, Bicarbonate, Base excess, Lactate levels in the blood

    Time: 1 day at ICU

    Description: evaluate glucose, haemoglobin, ureum, creatinine, total bilirubin levels (mg/dl) in patients with and without a DVT

    Measure: glucose, haemoglobin, ureum, creatinine, total bilirubin levels in the blood

    Time: 1 day at ICU

    Description: evaluate oxygen saturation, basophils, eosinophils, monocytes, neutrophils, haematocrit and prothrombine levels in the blood (%) in patients with and without a DVT

    Measure: oxygen saturation, basophils, eosinophils, monocytes, neutrophils, haematocrit and prothrombine levels in the blood

    Time: 1 day at ICU

    Description: evaluate white blood cells (x 10*9/L), red blood cells (x 10*12/L) and platelets levels (x 109/L) in the blood in patients with and without a DVT

    Measure: white blood cells, red blood cells and platelets in the blood

    Time: 1 day at ICU

    Description: evaluate PT (%)aPTT (sec)Fibrinogen (g/L)D-dimers (mg/L) PT (INR) (ratio) AST (U/L)ALT (U/L)Lactate dehydrogenase (U/L)Troponin T (ng/L)CRP (mg/L)Ferritin (mg/L) in the blood in patients with and without a DVT

    Measure: PT (%)aPTT (sec)Fibrinogen (g/L)D-dimers (mg/L) PT (INR) (ratio) AST (U/L)ALT (U/L)Lactate dehydrogenase (U/L)Troponin T (ng/L)CRP (mg/L)Ferritin (mg/L)in the blood

    Time: 1 day at ICU

    Description: revalence of co morbidities such as Cardiovascular disease, n (%) Hypertension, n (%) Diabetes, n (%) Respiratory disease, n (%) Malignancy, n (%) Chronic renal disease, n (%) Chronic liver disease, n (%) Chronic bowel disease, n (%) Chronic nerve disease, n (%) Cerebrovascular disease, n (%) HIV/AIDS, n (%) Haematological disease, n (%) Obesity, n (%) Rheumatological disease, n (%) Dementia, n (%) in patients with and without a DVT admitted at the ICU in 1 day

    Measure: prevalence of co-morbidities

    Time: 1 day at ICU

    Description: prevalence of vital signs such Temperature (°C) Breathing rate (#/min) Systolic blood pressure (mmHg) Mean arterial blood pressure (mmHg) Heart rate (#/min) Glasgow Coma Scale in patients with and without a DVT

    Measure: prevalence of vital signs at icu admission

    Time: at ICU admission

    Description: prevalance of complications such as ARDS Acute kidney failure Acute heart failure Septic shock Secondary infection Seizure Stroke Hyperglaecemia Hypoglaecemia during ICU stay in patients with and without DVT

    Measure: prevalence of complications during icu stay

    Time: from ICU admission to cross sectional moment (29/3/2020)

    Description: evaluation of treatment such as Antiviral treatment Antibiotic treatment Antifungal treatment Corticosteroid treatment CRRT IVIg treatment Plaquenil treatment during ICU stay in patients with and without DVT

    Measure: evaluation of treatment

    Time: from ICU admission to cross sectional moment (29/3/2020)

    Description: evaluation of the oxygen therapy such as Invasive mechanical ventilation FiO2 (mmHg) PEEP Length of ventilationA ECMO Invasive mechanical ventilation + ECMO Vasopressor/inotropic support Neuromuscular blocking agents Prone ventilation in patients with and without DVT

    Measure: evaluation of the oxygen therapy

    Time: from ICU admission to cross sectional moment (29/3/2020)

    HPO Nodes


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials

    Reports

    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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