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    HP:0012047: Hemeralopia

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (8)


    Name (Synonyms) Correlation
    drug3387 Probiotic and LC-PUFA Wiki 0.71
    drug1326 DigiVis visual acuity app Wiki 0.71
    drug2847 Non invasive visual acuity testing Wiki 0.71
    Name (Synonyms) Correlation
    drug525 BMS-986322 Wiki 0.71
    drug3442 Psychosocial stimulation and healthy eating education Wiki 0.71
    drug526 BMS-986322 Placebo Wiki 0.71
    drug4949 famotidine Wiki 0.71
    drug3195 Placebo Wiki 0.03

    Correlated MeSH Terms (4)


    Name (Synonyms) Correlation
    D015354 Vision, Low NIH 1.00
    D014786 Vision Disorders NIH 1.00
    D000550 Amblyopia NIH 0.71
    Name (Synonyms) Correlation
    D018352 Coronavirus Infections NIH 0.02

    Correlated HPO Terms (2)


    Name (Synonyms) Correlation
    HP:0000505 Visual impairment HPO 1.00
    HP:0000646 Amblyopia HPO 0.71

    Clinical Trials

    Navigate: Correlations   HPO

    There are 2 clinical trials


    1 Validity of at Home Visual Acuity Measurements for Telemedicine During Corona Virus (COVID-19) Pandemic

    Prompted by the current COVID-19 pandemic, the American Academy of Ophthalmology has recommended the use of telemedicine to continue ophthalmic care while maintaining patient and provider social distancing. As part of remote examinations, patients may be expected to perform home eye testing for visual acuity and the use of various home visual acuity charts have been proposed to provide clinicians with this vital data. However, the use of home visual acuity exams has not been validated in our patient population. This project aims to determine the efficacy and validity of measuring visual acuity at home with a printed-out ETDRS chart.

    NCT04391166
    Conditions
    1. Visual Impairment
    Interventions
    1. Other: Non invasive visual acuity testing
    MeSH:Coronavirus Infections Vision Disorders Vision, Low
    HPO:Hemeralopia Metamorphopsia Visual impairment

    Primary Outcomes

    Description: Best Visual Acuity per eye

    Measure: Best Corrected Visual Acuity (BCVA) Per Eye

    Time: From the time they sign the consent until we take their BCVA in clinic. Approximately 1-2 weeks.
    2 DigiVis: Validation of Self-testing Visual Acuity Web-based App to Aid Ophthalmic Telephone Consultations During Covid19 Lockdown and Subsequent Social Distancing Crisis

    This trial aims to assess the accuracy and test-retest variability of a new digital app which enables community visual acuity testing without requirement of an trained examiner.

    NCT04482387
    Conditions
    1. Visual Impairment
    2. Amblyopia Suspect
    Interventions
    1. Device: DigiVis visual acuity app
    MeSH:Amblyopia Vision Disorders Vision, Low
    HPO:Amblyopia Hemeralopia Metamorphopsia Visual impairment

    Primary Outcomes

    Description: Measurement bias in logMAR units between DigiVis testing and standard visual acuity testing score compared to

    Measure: Comparison of visual acuity measurement using DigiVis testing and standard visual acuity testing

    Time: within 30 days

    Description: Upper and lower levels of agreement measured in logMAR units

    Measure: Levels of Agreement between DigiVis testing and standard visual acuity testing

    Time: within 30 days

    Secondary Outcomes

    Description: Measurement of test-retest variability

    Measure: DigiVis test repeatability

    Time: within 30 days

    HPO Nodes


    HPO

    Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials

    Reports

    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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