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  • HP:0001645: Sudden cardiac death
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    HP:0001645: Sudden cardiac death

    Developed by Shray Alag, The Harker School
    Sections: Correlations, Clinical Trials, and HPO

    Correlations computed by analyzing all clinical trials.

    Navigate: Clinical Trials and HPO


    Correlated Drug Terms (1)


    Name (Synonyms) Correlation
    drug4857 blood donation SMS Wiki 0.58

    Correlated MeSH Terms (7)


    Name (Synonyms) Correlation
    D016757 Death, Sudden, Cardiac NIH 1.00
    D017180 Tachycardia, Ventricular NIH 1.00
    D013610 Tachycardia NIH 0.58
    Name (Synonyms) Correlation
    D003643 Death, NIH 0.50
    D007238 Infarction NIH 0.28
    D020521 Stroke NIH 0.24
    D009203 Myocardial Ischemia NIH 0.21

    Correlated HPO Terms (4)


    Name (Synonyms) Correlation
    HP:0004756 Ventricular tachycardia HPO 1.00
    HP:0001649 Tachycardia HPO 0.58
    HP:0001297 Stroke HPO 0.24
    Name (Synonyms) Correlation
    HP:0001658 Myocardial infarction HPO 0.21

    Clinical Trials

    Navigate: Correlations   HPO

    There is one clinical trial.


    1 Acute Cardiovascular Events Triggered by COVID-19-Related, Non-infectious Stress The Jordan COVID-9 caRdiovascular Events (JoCORE) Study

    The current COVID19 pandemic has afflicted almost the whole globe. The stress related to the pandemic, not the direct virus-related injury, can be potentially associated with acute cardiovascular events due to a large list of physical and psychosocial stresses. This study is a cross sectional study that will enroll patients evaluated during the COVID19 pandemic period for acute cardiovascular events.

    NCT04368637
    Conditions
    1. Acute Myocardial Infarction
    2. Ventricular Tachycardia
    3. Sudden Cardiac Death
    4. Stroke, Acute
    MeSH:Stroke Myocardial Infarction Tachycardia Tachycardia, Ventricular Death, Sudden, Cardiac Infarction Death
    HPO:Myocardial infarction Stroke Sudden cardiac death Tachycardia Ventricular tachycardia

    Primary Outcomes

    Description: Acute myocardial infarction as diagnosed by ST segment elevation or depression or inverted T wave on 12-lead EKG and elevated levels of cardiac troponins above the 99% of the normal values. A. Acute MI (STEMI and NSTEMI). B. Aborted on non-aborted sudden cardiac death not attributed to a known etiology. C. Sustained or non-sustained ventricular tachy-arrhythmia not attributed to a known etiology. D. ICD shocks. 3. Absence of suspected or confirmed infection with the COVID19 virus. 4. Definite physical or psycho-social stressful trigger appearing in relation to the COVID-19 situation (lock down stress, financial stress, anger, depression, fear, sorrow, death of a significant person, eating binges, smoking binges, physical stress [carrying walking for shopping and carrying excess weights] ..etc) as judged by a unanimous agreement of three investigators in the steering committee.

    Measure: Acute cardiovascular event triggered by COVID-19 stress

    Time: 4 months

    Description: Typical ventricular tachycardia on 12-lead EKG or EKG monitor.

    Measure: Ventricular tachycardia

    Time: 4 months

    Description: acute neurological symptoms of hemiparesis or dysrthria due to brain ischemia proven by computerized tomography or magnatic resonance

    Measure: acute stroke

    Time: 4 months

    Description: Finding an episode of ventricular tachycardia on interrogation of ICD tracing

    Measure: Implantable cardioverter defibrillator (ICD) shock

    Time: 4 months

    HPO Nodes


    Reports

    Data processed on December 13, 2020.

    An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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