This study proposes a simple and safe way of lowering this complicate rate, while improving graft recovering and protecting the graft as it recovers from the transplant. The investigators hypothesize that by maintaining a tight glucose control via a glucose-insulin clamp during surgery and 72 hours post-operatively the investigators will be able to lower the complication rate by 50%.

NCT01001273

Conditions

1. Postoperative Complications

Interventions

1. Other: Hyperinsulinemic Normoglycemic Clamp

MeSH:Postoperative Complications

Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Postoperative Complications Postoperative Complications null --- D20W ---

Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Postoperative Complications Postoperative Complications null --- D20W --- --- D20W ---