SNPMiner Trials by Shray Alag

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SNPMiner SNPMiner Trials (Home Page)


Report for Mutation D20W

Developed by Shray Alag, 2020-2021.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 Hyperinsulinemic Normoglycemic Clamp for Pancreas and Simultaneous Pancreas/Kidney Transplant Recipients

This study proposes a simple and safe way of lowering this complicate rate, while improving graft recovering and protecting the graft as it recovers from the transplant. The investigators hypothesize that by maintaining a tight glucose control via a glucose-insulin clamp during surgery and 72 hours post-operatively the investigators will be able to lower the complication rate by 50%.

NCT01001273
Conditions
  1. Postoperative Complications
Interventions
  1. Other: Hyperinsulinemic Normoglycemic Clamp
MeSH:Postoperative Complications

Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Postoperative Complications Postoperative Complications null --- D20W ---

Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Inclusion Criteria: - Male or female patient over 18 years of age - Patient is about to receive a pancreas or a simultaneous pancreas/kidney transplant - Able to give written informed consent prior to any study specific procedure Exclusion Criteria: - Multi-organ transplant other than kidney transplant - No central venous access available to deliver the D20W solution Postoperative Complications Postoperative Complications null --- D20W --- --- D20W ---

Primary Outcomes

Measure: The number of post-transplants all complications up to 30 days (Clavien grading).

Time: 30 days post-operative

Secondary Outcomes

Measure: The number of 30 days post-transplant serious medical complication (Clavien grade 3, 4)

Time: 30 days post-op

Measure: The length of hospital stay (days)

Time: Length of hospital stay (day 1 until discharge)


HPO Nodes