SNPMiner Trials by Shray Alag

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SNPMiner SNPMiner Trials (Home Page)


Report for Mutation R10C

Developed by Shray Alag, 2020-2021.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 Addressing the Hidden Patient - A Randomised-controlled Trial of a Tailored Group Intervention for Caregivers of Cancer Patients (PREPARE)

Background and study aims: Being a caregiver for someone with cancer can be very difficult emotionally. For many the patient is a family member or friend, and so this can cause the caregiver a great deal of psychological distress. There are currently very few studies looking into the effectiveness of psychological treatments for distressed caregivers of cancer patients. This study is looking at tailored group therapy program for carers of cancer givers. The aim of this study is to find out whether this program can help to lower levels of distress in cancer caregivers and help them to better cope with caring for someone with the illness.

NCT02739243
Conditions
  1. Distress in Caregivers of Cancer Patients
Interventions
  1. Behavioral: Tailored group intervention (PREPARE)
  2. Behavioral: Individual treatment as usual

measured using the Questionnaire on Stress in Caregivers of Cancer Patients Revised version (QSC-R10C). --- R10C ---

Time since initial diagnosis (of patient) not longer than six months previously 2. Significant distress against the background of the cancer disease (QSC-R10C exceeding 16 points) 3. Provision of informed consent 4. Aged 18 or over, either gender Exclusion Criteria: 1. Inability to give informed consent 2. Insufficient German language knowledge 3. Cognitive impairment impeding handling of questionnaires 4. Severe psychiatric disease (acute psychosis or acute suicidality) Inclusion Criteria: 1. --- R10C ---

Time since initial diagnosis (of patient) not longer than six months previously 2. Significant distress against the background of the cancer disease (QSC-R10C exceeding 16 points) 3. Provision of informed consent 4. Aged 18 or over, either gender Exclusion Criteria: 1. Inability to give informed consent 2. Insufficient German language knowledge 3. Cognitive impairment impeding handling of questionnaires 4. Severe psychiatric disease (acute psychosis or acute suicidality) Distress in Caregivers of Cancer Patients null --- R10C ---

Primary Outcomes

Description: measured using the Questionnaire on Stress in Caregivers of Cancer Patients Revised version (QSC-R10C)

Measure: Distress

Time: change from baseline distress at 1 week post treatment

Secondary Outcomes

Description: measured using the Patient Health Questionnaire-9 (PHQ-9)

Measure: Depression

Time: change from baseline depression at 1 week post treatment and at 6 months post treatment

Description: measured using the Generalized Anxiety Disorder-7 (GAD-7)

Measure: Anxiety

Time: change from baseline anxiety at 1 week post treatment and at 6 months post treatment

Description: measured using the Distress Thermometer (NCCN DT)

Measure: General distress

Time: change from baseline general distress at 1 week post treatment and at 6 months post treatment

Description: measured using the Supportive Care Needs Survey - Partners & Caregivers (SCNS-P&C-G)

Measure: Unmet needs

Time: change from baseline unmet needs at 1 week post treatment and at 6 months post treatment

Description: measured using the adapted General Perceived Self-Efficacy Scale

Measure: Self-efficacy in coping with the cancer disease

Time: change from baseline self-efficacy at 1 week post treatment and at 6 months post treatment

Description: measured via the number of visits with the individual primary care physician

Measure: Utilisation of primary healthcare

Time: change from baseline to 1 week post treatment and 6 months post treatment

Description: measured via the Positive Bonding Scale of the Group Questionnaire (GQ-D)

Measure: Positive bonding with the group

Time: change from baseline bonding at 1 week post treatment and 6 months post treatment


HPO Nodes