SNPMiner Trials by Shray Alag
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SNPMiner Trials (Home Page)
Report for Mutation G212A
Developed by Shray Alag, 2020-2021.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Serum Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ)in Obese Children and Adolescents.
The aim of this study is to investigate serum apelin levels as well as their possible association with G212A polymorphism of the apelin receptor in obese children and adolescents. So far apelin has been reported to be involved in the pathophysiology of various heart diseases such as cardiomyopathies and heart failure. According to recent reports in adults apelin seems to be associated with impaired glucose metabolism, particularly in newly diagnosed diabetes type 2 patients. Obesity is associated with insulin resistance and compensatory hyperinsulinemia leading to diabetes mellitus type 2 even in youngsters. The researchers will try to investigate the role of this new adipokine in order to early detect and to prevent similar entities in childhood obesity.
NCT01121172 Conditions
- Obesity
- Insulin Resistance
- Diabetes Mellitus Type 2
MeSH:Insulin Resistance Diabetes Mellitus, Type 2
HPO:Insulin resistance Type II diabetes mellitus
Serum Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ)in Obese Children and Adolescents.. Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ) The aim of this study is to investigate serum apelin levels as well as their possible association with G212A polymorphism of the apelin receptor in obese children and adolescents. --- G212A ---
Serum Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ)in Obese Children and Adolescents.. Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ) The aim of this study is to investigate serum apelin levels as well as their possible association with G212A polymorphism of the apelin receptor in obese children and adolescents. --- G212A --- --- G212A ---
Serum Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ)in Obese Children and Adolescents.. Apelin Levels and G212A Polymorphism of Apelin Receptor (APJ) The aim of this study is to investigate serum apelin levels as well as their possible association with G212A polymorphism of the apelin receptor in obese children and adolescents. --- G212A --- --- G212A --- --- G212A ---
Frequency of G212A Polymorphism of Apelin Receptor in Obese Children and Adolescents. --- G212A ---
Number of participants with Apelin Receptor Gene G212A polymorphism by genotype group. --- G212A ---
Primary Outcomes
Description: Apelin levels were measured in serum of participants, in fasting state
Measure: Serum Apelin Levels Time: First day after enrollment and after 8-hours of night fasting, at approximately 8:00 pm in the morningSecondary Outcomes
Description: Number of participants with Apelin Receptor Gene G212A polymorphism by genotype group
Measure: Frequency of G212A Polymorphism of Apelin Receptor in Obese Children and Adolescents Time: First day after enrollment