This study explores the association between single nucleotide polymorphism (Met11Thr) of surfactant protein D(SP-D) and susceptibility and prognosis of infectious keratitis.Met11Thr of SP-D of patients with keratitis and normal controls were compared.Allele and genotype frequencies of patients with keratitis and normal controls were determined by polymerase chain reaction with sequence specific primers(PCR-SSPs) .SP-D gene polymorphism of patients with keratitis and normal controls was detected by Sanger sequencing

NCT04213313

Conditions

1. Infectious Keratitis

Interventions

1. Drug: Treatment of bacterial keratitis
2. Drug: Treatment of fungal keratitis
3. Drug: Treatment of viral keratitis
4. Diagnostic Test: corneal scraping
5. Other: Sequencing

MeSH:Communicable Diseases Infection Keratitis

HPO:Keratitis

Association Between SNP of SP-D and Susceptibility and Prognosis of Infectious Keratitis This study explores the association between single nucleotide polymorphism (Met11Thr) of surfactant protein D(SP-D) and susceptibility and prognosis of infectious keratitis.Met11Thr of SP-D of patients with keratitis and normal controls were compared.Allele and genotype frequencies of patients with keratitis and normal controls were determined by polymerase chain reaction with sequence specific primers(PCR-SSPs) .SP-D gene polymorphism of patients with keratitis and normal controls was detected by Sanger sequencing Base type. --- Met11Thr ---