SNPMiner Trials by Shray Alag

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Report for Mutation E274Q

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials

1 The Effect of CYP2C8 E274Q, a Novel 23452 G>T SNP, on the Disposition of Rosiglitazone in Healthy Subjects: The Genetic Polymorphisms of CYP2C8 in a Korean Population

The genotype profile of CYP2C8 was analyzed in a Korean population. Frequency in multi-ethnic population and in vivo functionality of novel null allelic CYP2C8 variant were evaluated.

NCT01872780 Healthy Drug: Rosiglitazone Genetic: CYP2C8 genotype

The Effect of CYP2C8 E274Q, a Novel 23452 G>T SNP, on the Disposition of Rosiglitazone in Healthy Subjects: The Genetic Polymorphisms of CYP2C8 in a Korean Population. --- E274Q ---

Primary Outcomes

Description: 0h,0.33h,0.66h,1h,1.5h,2h,3h,4h,6h,8h,12h,24h

Measure: AUC

Time: 12hr

Secondary Outcomes

Description: 0h,0.33h,0.66h,1h,1.5h,2h,3h,4h,6h,8h,12h,24h

Measure: Cmax

Time: 12hr

HPO Nodes