SNPMiner Trials (Home Page)
Report for Mutation S65D
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Iron Supplement Effect Over Immune System and Neurobehavioral Child Development.
Objective: To evaluate the effect of Iron supplement with two different amounts (one in the higher limit and another in the lower limit of the suggested amount) according to the presence of mutations in the HFE gene in the physical, immune and neurobehavioral development in the 6 to 12 moth toddlers. Methodology: Subjects: 340 toddlers coming from Paediatric Serves of Sant Joan Hospital. Methods: At 6 and 12 months it done clinical history, food registry, biochemist determinations: haemoglobin, iron, transferrin, ferritin, reactive C protein and immune response (IL4, IL10, IL6 IFN, IgA, IgM, IgG, IgE). Mutations in the HFE gene: C282Y, H63D, S65D and hepcidin gene. Mental, psychomotor and behavioual development (Bayley Scales of Infant Development 2on Edition: 1993). We evaluate the level of language and communication (MacArthur), regulation and sensory process (Infant Toddler Symptom Checklist), familiar and environment surroundings (Scale Health General Parental Stress Index).
NCT02690675 Neurodevelopmental Disorders Lactation Dietary Supplement: Iron fortified formula milk MeSH:Neurodevelopmental Disorders
Mutations in the HFE gene: C282Y, H63D, S65D and hepcidin gene. --- C282Y --- --- H63D --- --- S65D ---
Primary Outcomes
Measure: Mental and psychomotor development with BSID (Bayley Scale of Infant Development) at 12 months. Time: 12 monthsSecondary Outcomes
Measure: Height at 12 months measured in centimeters Time: 12 monthsMeasure: Weight at 12 months measured in grams Time: 12 months
Measure: Head circumference at 12 months measured in centimeters Time: 12 months
Measure: Risk of infections at 12 months measured qualitatively from record of presence or not of various infections as bronchitis, rhinitis, otitis etc. Time: 12 months