SNPMiner Trials (Home Page)
Report for Mutation S9304A
Developed by Shray Alag, 2020.
SNP Clinical Trial Gene
There is one clinical trial.
Clinical Trials
1 Investigation of Thioredoxin-1 Family Protein Expression in Rectal Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at protein expression in tumor tissue samples from patients with stage II or stage III rectal cancer enrolled in clinical trial SWOG-9304.
NCT00972751 Colorectal Cancer MeSH:Rectal Neoplasms
HPO:Neoplasm of the rectum
S9304A Study of Protein Expression in Tumor Tissue Samples From Patients With Stage II or Stage III Rectal Cancer Enrolled in Clinical Trial SWOG-9304 RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. --- S9304A ---
Primary Outcomes
Measure: Expression of thioredoxin-1, thioredoxin-interacting protein, and hypoxia inducible factor-1 alpha Time: upon testing of specimensMeasure: Correlation of expression of these proteins with tumor stage, disease-free survival, overall survival, and risk of recurrence Time: upon provision of expression to Statistical Center