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D000068376: Compassion Fatigue

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO


Correlated Drug Terms (9)


Name (Synonyms) Correlation
drug491 Biological: mRNA-1273: 100 mcg Wiki 0.71
drug1451 Health Enhancement Program Wiki 0.71
drug492 Biological: mRNA-1273: 50 mcg Wiki 0.71
Name (Synonyms) Correlation
drug3287 Sudarshan Kriya Yoga (SKY) Wiki 0.71
drug1530 Hydroxychloroquine - Daily dosing Wiki 0.71
drug1975 Matched Placebo Hydroxychloroquine Wiki 0.71
drug2065 MinnRAP Peer Support Program Wiki 0.71
drug1531 Hydroxychloroquine - Weekly Dosing Wiki 0.50
drug2505 Placebo Wiki 0.03

Correlated MeSH Terms (8)


Name (Synonyms) Correlation
D000067073 Psychological Trauma NIH 0.82
D015775 Fractures, Stress NIH 0.71
D000073397 Occupational Stress NIH 0.41
Name (Synonyms) Correlation
D013315 Stress, Psychological NIH 0.14
D040921 Stress Disorders, Traumatic NIH 0.13
D013313 Stress Disorders, Post-Traumatic NIH 0.12
D004194 Disease NIH 0.11
D001008 Anxiety Disorders NIH 0.11

Correlated HPO Terms (0)


Name (Synonyms) Correlation

Clinical Trials

Navigate: Correlations   HPO

There are 2 clinical trials


1 Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness (BREATH): an RCT for Frontline Hospital and Long-term Care Home Staff Managing the COVID-19 Pandemic

This study will examine the feasibility of conducting an online Randomized Controlled Trial (RCT) in frontline hospital and long term care healthcare staff in managing COVID-19 patients in London, ON. The study will randomize participants to Sudarshan Kriya Yoga (SKY) or a Health Enhancement Program (HEP).

NCT04368676
Conditions
  1. Job Stress
  2. Workplace Stress
  3. Compassion Fatigue
  4. Psychological Trauma
  5. Healthcare Workers
  6. Healthcare Providers
Interventions
  1. Other: Sudarshan Kriya Yoga (SKY)
  2. Other: Health Enhancement Program
MeSH:Compassion Fatigue Occupational Stress Psychological Trauma

Primary Outcomes

Description: The number of participants recruited per month will be calculated as a feasibility measure.

Measure: Rate of participant recruitment

Time: 1 year

Description: The retention rate of participants will be calculated as a feasibility measure.

Measure: Rate of retention

Time: 1 year

Description: The completeness of study assessments will be assessed as a feasibility measure by calculating the missing percentage of data in case report forms.

Measure: Completeness of data entry

Time: 1 year

Description: The cost of both study interventions will be calculated to assess the total study cost for interventions and the cost per participant. This information will be used as a feasibility measure.

Measure: Cost of interventions

Time: 1 year

Description: The total of unexpected costs will be calculated as a feasibility measure.

Measure: Unexpected costs

Time: 1 year

Secondary Outcomes

Description: The Athens Insomnia Scale will be used to assess insomnia. This scale is an 8-item, self-rated measure of the extent of sleep difficulties over the last 30 days with each item representing a different aspect of sleep (e.g. "Overall Quality of Sleep"). Ratings are from 0 to 4, with 0 being no difficulty with the item and 4 being the most difficulty with the item. Higher overall scores on this scale indicate higher difficulties with sleep.

Measure: Change in Athens Insomnia Scale

Time: Change from Week 0 to week 3 and to week 5

Description: The Generalized Anxiety Disorder 7-item scale (each scored 0-3) is a self-rated measure of anxiety and has been validated for the diagnosis of Generalized Anxiety Disorder in the adult population. Scores range from 0 to 21. Higher scores indicate greater anxiety symptoms (5-9, mild anxiety; 10-14, moderate anxiety; 15-21 severe anxiety).

Measure: Change in Generalized Anxiety Disorder 7-item scale

Time: Change from Week 0 to week 3 and to week 5

Description: The Patient Health Questionnaire (PHQ-9) is a 9-item, self-rated measure of depression which has been validated for screening a major depressive episode in adults. Total scores indicate various levels of depression: 0-4, no depression; 5-9, mild depression; 10-14, moderate depression; 15-19, moderately severe depression; 20-27, severe depression.

Measure: Change in Patient Health Questionnaire 9

Time: Change from Week 0 to week 3 and to week 5

Description: The Connor-Davidson Resilience Scale (CD-RISC) is a brief self-rated assessment tool that comprises of 10 items, each rated on a 5-point Likert scale (0 = not true at all to 4 = true nearly all the time). Higher scores reflect greater resilience, which is a measure of one's ability to cope with stress. The scale demonstrated strong reliability and validity and has been studied in a variety of populations including medical personnel, nurses, social workers and physicians).

Measure: Change in Connor-Davidson Resilience Scale

Time: Change from Week 0 to week 3 and to week 5
2 The Professional Peer Resilience Initiative: Leveraging a Data-Driven Model to Maximize the Resilience of Healthcare Workers During the COVID-19 Pandemic

The Professional Peer Resilience Initiative (PPRI) study is an observational study aimed at understanding how symptoms of traumatic stress and resilience evolve over time in the University of Minnesota (UMN) healthcare workforce during the coronavirus disease 2019 (COVID-19) pandemic. The study is being conducted concurrently with a UMN peer support program called the MinnRAP program and will remotely administer quality of life and mental health surveys to healthcare workers before they start the MinnRAP program and throughout their participation in the program.

NCT04396600
Conditions
  1. Stress
  2. Stress Disorder
  3. Stress, Psychological
  4. Trauma, Psychological
  5. Anxiety
  6. Anxiety State
  7. Post Traumatic Stress Disorder
  8. Secondary Traumatic Stress
  9. Professional Quality of Life
  10. Stress Related Disorder
  11. Stress Reaction
  12. Stress Risk
  13. Mental Resilience
  14. Emotional Resilience
Interventions
  1. Behavioral: MinnRAP Peer Support Program
MeSH:Disease Compassion Fatigue Fractures, Stress Anxiety Disorders Stress Disorders, Traumatic Stress Disorders, Post-Traumatic Stress, Psychological Psychological Trauma

Primary Outcomes

Description: Professional Quality of Life Questionnaire (proQOL): min score of 10; max score of 50; higher scores mean worse outcome

Measure: Change in professional quality of life

Time: Before peer support program, through study completion (an average of 7 months)

Secondary Outcomes

Description: Stress Risk & Resilience Self-Index: min score 0; max score of 12; higher scores mean worse outcome

Measure: Change in mental health symptoms and resilience markers

Time: Before peer support program, through study completion (an average of 7 months)

HPO Nodes


HPO

Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


HPO Nodes


Reports

Data processed on September 26, 2020.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

Drug Reports   MeSH Reports   HPO Reports  

Interventions

4,180 reports on interventions/drugs

MeSH

691 reports on MeSH terms

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263 reports on HPO terms

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Alphabetical index of all Terms

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