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D001927: Brain Diseases

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO


Correlated Drug Terms (14)


Name (Synonyms) Correlation
drug1122 EEG Wiki 0.50
drug2713 Pulse oximetry Wiki 0.50
drug772 Chest physiotherapy using a non-invasive oscillating device Wiki 0.50
Name (Synonyms) Correlation
drug2890 Reverse-transcription polymerase chain reaction (RT-PCR) Wiki 0.50
drug692 CT-scan Wiki 0.50
drug766 Change in preference to surgery under COVID-19 pandemic. Wiki 0.50
drug726 Cannabis, Medical Wiki 0.50
drug771 Chest computed tomography (CT) Wiki 0.50
drug1135 EP Wiki 0.50
drug1343 Follow up Wiki 0.35
drug529 Blood tests Wiki 0.35
drug422 BNT162b2 Wiki 0.35
drug421 BNT162b1 Wiki 0.29
drug2505 Placebo Wiki 0.02

Correlated MeSH Terms (28)


Name (Synonyms) Correlation
D020196 Trauma, Nervous System NIH 0.50
D000070627 Chronic Traumatic Encephalopathy NIH 0.50
D005879 Tourette Syndrome NIH 0.50
Name (Synonyms) Correlation
D000690 Amyotrophic Lateral Sclerosis NIH 0.35
D000755 Anemia, Sickle Cell NIH 0.35
D016472 Motor Neuron Disease NIH 0.35
D001714 Bipolar Disorder NIH 0.35
D012640 Seizures NIH 0.29
D005356 Fibromyalgia NIH 0.25
D003693 Delirium NIH 0.22
D010300 Parkinsonian NIH 0.19
D015212 Inflammatory Bowel Diseases NIH 0.19
D000070642 Brain Injuries, Traumatic NIH 0.18
D003424 Crohn Disease NIH 0.16
D001930 Brain Injuries, NIH 0.15
D059350 Chronic Pain NIH 0.15
D012598 Scoliosi NIH 0.14
D009103 Multiple Sclerosis NIH 0.14
D016638 Critical Illness NIH 0.13
D040921 Stress Disorders, Traumatic NIH 0.09
D014947 Wounds and Injuries NIH 0.09
D013313 Stress Disorders, Post-Traumatic NIH 0.09
D004194 Disease NIH 0.08
D013577 Syndrome NIH 0.05
D003141 Communicable Diseases NIH 0.04
D007239 Infection NIH 0.02
D045169 Severe Acute Respiratory Syndrome NIH 0.02
D018352 Coronavirus Infections NIH 0.02

Correlated HPO Terms (8)


Name (Synonyms) Correlation
HP:0001298 Encephalopathy HPO 1.00
HP:0006802 Abnormal anterior horn cell morphology HPO 0.50
HP:0007354 Amyotrophic lateral sclerosis HPO 0.50
Name (Synonyms) Correlation
HP:0100754 Mania HPO 0.35
HP:0001250 Seizure HPO 0.29
HP:0002037 Inflammation of the large intestine HPO 0.19
HP:0012532 Chronic pain HPO 0.17
HP:0100280 Crohn's disease HPO 0.16

Clinical Trials

Navigate: Correlations   HPO

There are 4 clinical trials


1 Outcomes Mandate National Integration With Cannabis as Medicine for Prevention and Treatment of COVID-19

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

NCT03944447
Conditions
  1. Chronic Pain
  2. Chronic Pain Syndrome
  3. Chronic Pain Due to Injury
  4. Chronic Pain Due to Trauma
  5. Fibromyalgia
  6. Seizures
  7. Hepatitis C
  8. Cancer
  9. Crohn Disease
  10. HIV/AIDS
  11. Multiple Sclerosis
  12. Traumatic Brain Injury
  13. Sickle Cell Disease
  14. Post Traumatic Stress Disorder
  15. Tourette Syndrome
  16. Ulcerative Colitis
  17. Glaucoma
  18. Epilepsy
  19. Inflammatory Bowel Diseases
  20. Parkinson Disease
  21. Amyotrophic Lateral Sclerosis
  22. Chronic Traumatic Encephalopathy
  23. Anxiety
  24. Depression
  25. Insomnia
  26. Autism
  27. Opioid-use Disorder
  28. Bipolar Disorder
  29. Covid19
  30. SARS-CoV Infection
  31. COVID-19
  32. Corona Virus Infection
  33. Coronavirus
Interventions
  1. Drug: Cannabis, Medical
MeSH:Infection Communicable Diseases Coronavirus Infections Severe Acute Respiratory Syndrome Fibromyalgia Crohn Disease Inflammatory Bowel Diseases Parkinson Disease Multiple Sclerosis Brain Injuries Brain Injuries, Traumatic Seizures Moto Motor Neuron Disease Amyotrophic Lateral Sclerosis Brain Diseases Tourette Syndrome Chronic Traumatic Encephalopathy Anemia, Sickle Cell Disease Syndrome Sclerosis Chronic Pain Wounds and Injuries Stress Disorders, Traumatic Bipolar Disorder Stress Disorders, Post-Traumatic
HPO:Abnormal anterior horn cell morphology Amyotrophic lateral sclerosis Bilateral tonic-clonic seizure Bipolar affective disorder Chronic pain Crohn's disease Encephalopathy Focal-onset seizure Generalized-onset seizure Inflammation of the large intestine Mania Seizure

Primary Outcomes

Description: Covid-19 infection rates in cannabis users will be compared to rates in the general population. Our online questionnaire responses will compare infection rates of cannabis users in this study against the Johns Hopkins University Coronavirus Research Center data (https://coronavirus.jhu.edu).

Measure: Prevention of COVID-19

Time: Five years

Description: Severity of persistent symptoms in cannabis users testing positive for active infection and/or antibodies will also be compared to the general population. Patients will answer the widely used FLU-PRO questionnaire, which asks about flu symptoms and severity, to capture diagnoses, symptoms, and medical interventions related to COVID-19. The data from cannabis user patients will be compared with national and international data surveys, such as the Covid Symptom Study (https://covid.joinzoe.com/us-2).

Measure: Treatment of COVID-19

Time: Five years

Description: The primary objective is to assess the efficacy and safety of medical cannabis as medicine for treatment of chronic pain and other chronic debilitating diseases. Pain will be measured by Brief Pain Inventory (BPI) numeric scale. Change from baseline in BPI will be assessed at 3-month intervals. For prospective associations between cannabis use and outcomes, use of a lagged mixed-effects models will examine temporal associations between cannabis use and pain severity, opioid sparing, and patient satisfaction. Data will be analyzed from baseline and the annual follow-up waves.

Measure: Treatment of Symptoms

Time: Five years

Secondary Outcomes

Description: Secondary objectives include evaluating increases or decreases in quality of life, and increases or decreases in concomitant opioid use. Satisfaction with treatment will be measured by a Visual Analog Score (VAS). Change From baseline in Satisfaction with treatment measured by (VAS) be assessed at 3-month intervals.

Measure: Cannabis Impact on Quality of Life

Time: Five years

Description: Tertiary objectives will examine preferences for routes of administration, and preferences for THC / CBD ratios. Categorical factors will be summarized using frequencies and percentages, while continuous measure distributions will be described using means, standard deviations, and quartiles of interest.

Measure: Cannabis Route and Dosing

Time: Five years

Description: Incidence of Treatment-Related Adverse Events will be measured by Physician Global Assessment (PGA) numeric scale. Number of participants with Treatment-Related Adverse Events will be assessed by CTCAE v4.0.

Measure: Monitoring Adverse Events

Time: Five years
2 Outcomes in Patients With Acute Encephalopathy and SARS-Cov-2 Infection

Infection with SARS-CoV-2 or severe acute respiratory syndrome coronarvirus type 2 was highlighted in December 2019 in the city of Wuhan in China, responsible for an pandemic evolution since March 11, 2020. The infection affects all ages of life, although affecting children in a very small proportion of cases. The typical presentation of the disease combines fever (98%), cough (76%), myalgia and asthenia (18%) as well as leukopenia (25%) and lymphopenia (63%). Upper airway involvement rare. The main clinical presentation requiring hospitalization of infected patients is that of atypical pneumonia which may require critical care management (27%), and progress to an acute respiratory distress syndrome (67%) involving life-threatening conditions in almost 25% of patients diagnosed with SARS-CoV-2 infection. Other organ damage have been reported, mainly concerning kidney damage (29%) which may require renal replacement therapy in approximately 17% of patients. Neurological damage has been very rarely studied, yet reported in 36% of cases in a study including patients of varying severity. Finally, the mortality associated with this emerging virus is high in patients for whom critical care management is necessary, reported in 62% of patients. We therefore propose a prospective observational study which aim at reporting the prevalence of acute encephalopathy at initial management in Critical/Intensive care or Neurocritical care , to report its morbidity and mortality and to identify prognostic factors.

NCT04320472
Conditions
  1. COVID-19
  2. Encephalopathy
  3. Critically Ill
Interventions
  1. Other: Follow up
MeSH:Brain Diseases Critical Illness
HPO:Encephalopathy

Primary Outcomes

Description: ratio of patients with acute encephalopathy among the total of patients with SARS-Cov-2 infection at Critical/Intensive care or Neurocritical care admission

Measure: prevalence

Time: at Critical/Intensive care or Neurocritical care admission

Secondary Outcomes

Description: A favorable outcome is defined by a Glasgow Outcome Scale (GOS) of 5. The Glasgow Outcome Scale (GOS) will be determined patients charts review, phone call, and/or general practitioner interview conducted by an independent assessor. The GOS score : [1: Death, 2: Persistent vegetative state, 3: Severe disability, 4: Moderate disability, 5 : Low disability]

Measure: Favorable outcome

Time: 3 months

Description: A favorable outcome is defined by a Glasgow Outcome Scale Extended (GOSe) >= 5. The Glasgow Outcome Scale Extended (GOSe) will be determined patients charts review, phone call, and/or general practitioner interview conducted by an independent assessor. The GOSe score : [1: Death, 2: Persistent vegetative state, 3: Severe disability Lower, 4: Severe disability Upper, 5: Moderate disability Lower, 6: Moderate disability Upper, 7 : Good recovery lower, 8 : Good recovery Upper]

Measure: Favorable outcome

Time: 3 months
3 Biomarker-guided Assessment of Neurocognitive Impairment in Patients With COVID-19 - a Multicenter Case-control Study

Delirium and acute neurocognitive impairment are increasingly observed in adult and pediatric patients with COVID-19. Prospective clinical studies combining clinical and laboratory examinations including specific biomarkers of neuroaxonal injury were not performed for COVID-19. The value of biomarkers of neuroaxonal injury was proven in preliminary studies. These biomarkers could thus contribute to the systematic detection of neurocognitive impairment in patients with COVID-19. Due to worldwide increasing numbers of hospitalized patients with COVID-19, biomarkers of neuroaxonal injury are highly valuable to detect and monitor cognitive impairment, especially with regard to limited resources available to perform time-consuming brain imaging. Biomarkers of neuroaxonal injury are therefore not only of great interest to detect neurocognitive impairment but also to quantify the severity of brain injury in patients with COVID-19.

NCT04359914
Conditions
  1. Critical Illness
  2. COVID-19
  3. Central Nervous System Injury
  4. Delirium
  5. Encephalopathy
MeSH:Delirium Brain Diseases Trauma, Nervous System Critical Illness
HPO:Encephalopathy

Primary Outcomes

Description: Assessment of neurocognitive impairment using validated tools

Measure: Incidence of delirium/neurocognitive impairment in adult and pediatric patients with COVID-19 compared to patients without COVID-19

Time: Day 90

Description: Measurement of biomarker levels (e.g. NSE, S100B, neurofilament proteins) derived from blood samples

Measure: Change in neuroaxonal injury biomarker levels in patients with COVID-19 compared to patients without COVID-19

Time: Change from baseline biomarker levels at day 28

Description: Assessment of the neurocognitive performance of patients using validated tests (e.g. Short Blessed Test)

Measure: Neurocognitive 3-months outcome in patients with COVID-19 compared to patients without COVID-19

Time: Day 90

Description: Assessment of the change in the neurocognitive performance of patients using validated tests (e.g. IQCODE)

Measure: Neurocognitive 3-months outcome in patients with COVID-19 compared to patients without COVID-19

Time: Change from baseline IQCODE results at day 90

Secondary Outcomes

Description: Assessment of the overall quality of life using validated tests [e.g. Modified Rankin Scale with a range from 0 (no symptoms) to 6 (dead)]

Measure: Quality of life in patients with COVID-19 compared to patients without COVID-19 after hospital discharge

Time: Day 90

Description: Cumulative days in hospital

Measure: Length of hospital stay in patients with COVID-19 compared to patients without COVID-19

Time: 1 year

Description: Survival after 90 days

Measure: 90-day survival in patients with COVID-19 compared to patients without COVID-19

Time: Day 90
4 Determination of Acute Encephalopathy Predictors in Patients With COVID-19

The SARS-CoV-2 infection was detected in December 2019 in Wuhan City, China. The infection affects all age groups, although childhood is the lowest proportion of those affected. The main clinical manifestations that require hospitalization of infected patients are SARS pneumonia, which may require treatment in the intensive care unit (27%) and its progression into acute respiratory distress syndrome (67%) with life-threatening conditions in almost 25% of patients diagnosed with "SARS-CoV-2 infection". Nervous system damage with SARS-CoV-2 infection has been practically not investigated, but neurological disorders have been reported in 36% of these patients. Finally, the mortality rate associated with the new virus is high in patients who require treatment in intensive care units (62% of cases). Therefore, we are conducting a prospective study to identify acute encephalopathy predictors in patients with COVID-19.

NCT04405544
Conditions
  1. Encephalopathy
  2. COVID
Interventions
  1. Diagnostic Test: CT-scan
  2. Diagnostic Test: EEG
  3. Diagnostic Test: EP
  4. Diagnostic Test: Pulse oximetry
  5. Diagnostic Test: Blood tests
MeSH:Brain Diseases
HPO:Encephalopathy

Primary Outcomes

Description: The percentage of patients who have developed encephalopathy

Measure: The percentage of patients who have developed encephalopathy

Time: 10 days

HPO Nodes


HP:0001298: Encephalopathy
Genes 351
CHEK2 DNM1 ASNS KMT2E NDUFAF5 CHD2 GLUL SYNJ1 SUCLA2 ATP6V1A SCN3A AMACR RANBP2 SLC25A13 SLC13A5 COX1 SLC22A5 TSFM SCN8A ND2 ACTL6B RNASEH2C SLC6A9 NUS1 SPTAN1 CLP1 TRNF CNKSR2 NADK2 TREX1 PARS2 GABRB3 DPM2 ND3 SLC1A2 PCCB GRIN1 ARV1 ADAM22 CPLX1 ATP6V1A NDUFAF1 NDUFV2 BOLA3 GPR35 CHD2 SLC1A2 GCDH KCNT1 TRAK1 TRNC COG8 NEUROD2 SCN8A ATP1A3 HADH PNPT1 SYNJ1 HADH CDKL5 MEF2C COQ2 WWOX ACY1 DHDDS TRNK TRNL1 ND1 ND4 HNRNPU TRAK1 PPP3CA NDUFS3 TUFM CNPY3 BSCL2 NDUFV2 SCN1A ATP5F1A CAD HIBCH EEF1A2 SIK1 SERPINI1 CYC1 NTRK2 NAXD WDR45 TCF4 COX3 TRNQ KCNB1 GABRB1 FADD FADD HCN1 DENND5A SLC25A1 GABRA2 GBA NDUFB11 NDUFS1 GCSH PIGP ALG9 CACNA1A MDH2 NECAP1 DLD TBCD RNASEH2B NRXN1 CYTB PCCA TRNV LIPT2 CUX2 TIMMDC1 NDUFAF8 NDUFB10 CACNA1B HTRA1 WWOX TRAPPC12 COX3 TIMM50 NADK2 UNC80 SERAC1 COQ4 UGDH AP2M1 PIGA KCNQ2 SLC25A20 FCSK ATP5F1D MST1 PMPCB CUX2 NDUFS6 FOXRED1 GLDC NBAS SZT2 NDUFA11 XIAP KYNU TRNS2 ND1 CYFIP2 GALC NDUFS4 NDUFAF4 TRNQ DOCK7 MDM2 SLC19A3 TRNK PNPO CPT2 ACAD9 COQ9 AP3B2 EEF1A2 PNKP TRNS1 KCNB1 CYFIP2 TCF4 GRIN2D CLPB COG8 NDUFB3 SLC12A3 STAG1 STXBP1 TRNH NDUFS8 NAGS NDUFAF3 LIAS FGF12 NDUFAF4 TMEM126B NUS1 NDUFAF2 CACNA1A GLYCTK TBC1D24 MECP2 ETHE1 CCDC88A DNM1 SCN2A BSCL2 NTRK2 GABRG2 GRIN2D KCNQ2 DNM1 CPT1A CLCN4 COX2 TRNF RNF13 GBA GABRA1 TRNW GABRB2 GCDH SLC6A1 SLC2A1 SLC25A22 CLTC TGFB1 DGUOK PNPO ARHGEF9 GABRG2 ITPA ROGDI ATAD1 CLCNKB TK2 CACNA2D2 CACNA1E NECAP1 ZNHIT3 KCNQ5 NDUFA6 SZT2 NRXN1 NDUFA6 LYRM7 SLC25A15 NDUFS6 FBLN1 D2HGDH PRNP TBCE TMEM70 TSEN54 AARS1 STXBP1 IBA57 NDUFS3 UBA5 SUCLG1 NDUFS2 STAT2 NDUFV1 ARV1 TRNS2 GUF1 GNAO1 TBCK PACS2 PCK1 AP3B2 ACSF3 ATP5F1A CARS2 NDUFS4 YWHAG COX1 CDKN2A SH2D1A TWNK GLS TRNW CHD2 DNM1L ND5 NDUFA1 ARX PARS2 SLC25A15 NDUFA11 PLCB1 SLC19A3 MPC1 TBCE RANBP2 ND6 TP53 TH SLC35A1 KCNA2 ND5 CARS2 SLC22A5 HMGCL NDUFAF1 SYNGAP1 PPP3CA FBXL4 GABRB2 CNTNAP2 KCNT2 NDUFAF2 COX15 ARHGEF9 NAXE BCS1L ACY1 CACNA1B KYNU DLD TBC1D24 NDUFB3 GPT2 FRRS1L GRIN2B GABRB3 SCN1A TRNS1 NDUFB9 ST3GAL3 COX2 SLC25A22 FGF12 SLC13A5 DHDDS ACAD9 ETHE1 SLC35A2 PSAP GABRA5 UGT1A1 KCNA2 SCN1B MAPK10 UBA5 SIK1 KCNA2 HCN1 SLC25A12 SCN3A AMT ND6 NDUFS7 AARS1 TRNL1 SYNGAP1 NDUFS7 GABBR2 TRIT1 ND1 PHACTR1 NUBPL
Protein Mutations 1
A3243G
SNP 0

HPO

Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


HPO Nodes


HP:0001298: Encephalopathy
Genes 351
CHEK2 DNM1 ASNS KMT2E NDUFAF5 CHD2 GLUL SYNJ1 SUCLA2 ATP6V1A SCN3A AMACR RANBP2 SLC25A13 SLC13A5 COX1 SLC22A5 TSFM SCN8A ND2 ACTL6B RNASEH2C SLC6A9 NUS1 SPTAN1 CLP1 TRNF CNKSR2 NADK2 TREX1 PARS2 GABRB3 DPM2 ND3 SLC1A2 PCCB GRIN1 ARV1 ADAM22 CPLX1 ATP6V1A NDUFAF1 NDUFV2 BOLA3 GPR35 CHD2 SLC1A2 GCDH KCNT1 TRAK1 TRNC COG8 NEUROD2 SCN8A ATP1A3 HADH PNPT1 SYNJ1 HADH CDKL5 MEF2C COQ2 WWOX ACY1 DHDDS TRNK TRNL1 ND1 ND4 HNRNPU TRAK1 PPP3CA NDUFS3 TUFM CNPY3 BSCL2 NDUFV2 SCN1A ATP5F1A CAD HIBCH EEF1A2 SIK1 SERPINI1 CYC1 NTRK2 NAXD WDR45 TCF4 COX3 TRNQ KCNB1 GABRB1 FADD FADD HCN1 DENND5A SLC25A1 GABRA2 GBA NDUFB11 NDUFS1 GCSH PIGP ALG9 CACNA1A MDH2 NECAP1 DLD TBCD RNASEH2B NRXN1 CYTB PCCA TRNV LIPT2 CUX2 TIMMDC1 NDUFAF8 NDUFB10 CACNA1B HTRA1 WWOX TRAPPC12 COX3 TIMM50 NADK2 UNC80 SERAC1 COQ4 UGDH AP2M1 PIGA KCNQ2 SLC25A20 FCSK ATP5F1D MST1 PMPCB CUX2 NDUFS6 FOXRED1 GLDC NBAS SZT2 NDUFA11 XIAP KYNU TRNS2 ND1 CYFIP2 GALC NDUFS4 NDUFAF4 TRNQ DOCK7 MDM2 SLC19A3 TRNK PNPO CPT2 ACAD9 COQ9 AP3B2 EEF1A2 PNKP TRNS1 KCNB1 CYFIP2 TCF4 GRIN2D CLPB COG8 NDUFB3 SLC12A3 STAG1 STXBP1 TRNH NDUFS8 NAGS NDUFAF3 LIAS FGF12 NDUFAF4 TMEM126B NUS1 NDUFAF2 CACNA1A GLYCTK TBC1D24 MECP2 ETHE1 CCDC88A DNM1 SCN2A BSCL2 NTRK2 GABRG2 GRIN2D KCNQ2 DNM1 CPT1A CLCN4 COX2 TRNF RNF13 GBA GABRA1 TRNW GABRB2 GCDH SLC6A1 SLC2A1 SLC25A22 CLTC TGFB1 DGUOK PNPO ARHGEF9 GABRG2 ITPA ROGDI ATAD1 CLCNKB TK2 CACNA2D2 CACNA1E NECAP1 ZNHIT3 KCNQ5 NDUFA6 SZT2 NRXN1 NDUFA6 LYRM7 SLC25A15 NDUFS6 FBLN1 D2HGDH PRNP TBCE TMEM70 TSEN54 AARS1 STXBP1 IBA57 NDUFS3 UBA5 SUCLG1 NDUFS2 STAT2 NDUFV1 ARV1 TRNS2 GUF1 GNAO1 TBCK PACS2 PCK1 AP3B2 ACSF3 ATP5F1A CARS2 NDUFS4 YWHAG COX1 CDKN2A SH2D1A TWNK GLS TRNW CHD2 DNM1L ND5 NDUFA1 ARX PARS2 SLC25A15 NDUFA11 PLCB1 SLC19A3 MPC1 TBCE RANBP2 ND6 TP53 TH SLC35A1 KCNA2 ND5 CARS2 SLC22A5 HMGCL NDUFAF1 SYNGAP1 PPP3CA FBXL4 GABRB2 CNTNAP2 KCNT2 NDUFAF2 COX15 ARHGEF9 NAXE BCS1L ACY1 CACNA1B KYNU DLD TBC1D24 NDUFB3 GPT2 FRRS1L GRIN2B GABRB3 SCN1A TRNS1 NDUFB9 ST3GAL3 COX2 SLC25A22 FGF12 SLC13A5 DHDDS ACAD9 ETHE1 SLC35A2 PSAP GABRA5 UGT1A1 KCNA2 SCN1B MAPK10 UBA5 SIK1 KCNA2 HCN1 SLC25A12 SCN3A AMT ND6 NDUFS7 AARS1 TRNL1 SYNGAP1 NDUFS7 GABBR2 TRIT1 ND1 PHACTR1 NUBPL
Protein Mutations 1
A3243G
SNP 0

Reports

Data processed on September 26, 2020.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

Drug Reports   MeSH Reports   HPO Reports  

Interventions

4,180 reports on interventions/drugs

MeSH

691 reports on MeSH terms

HPO

263 reports on HPO terms

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Alphabetical index of all Terms

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