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D005317: Fetal Growth Retardation

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug1241 Exercise program Wiki 1.00
drug1457 Healthy lifestyle advise Wiki 1.00

Correlated MeSH Terms (4)


Name (Synonyms) Correlation
D046110 Hypertension, Pregnancy-Induced NIH 1.00
D000078064 Gestational Weight Gain NIH 1.00
D015430 Weight Gain NIH 1.00
Name (Synonyms) Correlation
D011248 Pregnancy Complications NIH 0.33

Correlated HPO Terms (0)


Name (Synonyms) Correlation

Clinical Trials

Navigate: Correlations   HPO

There is one clinical trial.


1 Active Pregnancy, Prevention Against the Effects of COVID-19

Historically and traditionally, the recommendations related to physical exercise during pregnancy have been based more on moral or cultural issues than on scientific evidence. During some phases of history, pregnancy has meant a period of seclusion for women (not only physical). One of the adverse consequences has been the common recommendation of rest as a general rule for pregnant women. Scientific evidence from recent years has achieved a better understanding of the process of pregnancy and childbirth as well as maternal and fetal responses to exercise. Currently, both from a scientific and clinical/obstetric point of view, there is no doubt about the benefits of an active pregnancy for entire body of pregnant woman, and even her child. In fact, risks of a sedentary lifestyle are applicable to the pregnancy situation, even more with important associated complications during pregnancy and postpartum period. Unfortunately, the impact of COVID-19 has caused an unprecedented global crisis, in this sense the necessary measures taken by the different administrations, especially in terms of confinement causes (from now on) a large number of complications affecting different populations. In summary a complex situation without established prevention strategies exists. The pregnant population is, due to the nature of the gestation and delivery process, one of the population groups with the highest risk of adverse outcomes and associated complications and whose consequences include the mother, fetus, newborn and even children. According to an important body of scientific literature and based on an epigenetic effect, the intrauterine environment can be a determining factor for the future human being to evolve regardless of complications and pathologies (cardiovascular, metabolic, psychic, emotional). This is demonstrated by numerous recent scientific evidences that confirm the unfortunate association between an adverse intrauterine environment (due to various factors) and observable postnatal pathologies in infants. In addition, current publications report the large number and variety of alterations that the COVID-19 situation causes in pregnant women and that includes the entire female organism. This complex situation does not only affect aspects of a physical or physiological nature, but also psychic and emotional factors. In summary, a new state of confinement or similar situations in the near future (impossibility of groupings, distance between people), avoid during the daily life of pregnant women one of the important and recent recommendations made by the international scientific community: a pregnancy physically active. This is especially relevant, due to the dangerous association between complications of a psychological or emotional nature during pregnancy with pre, peri and postnatal disorders (low birth weights, perinatal complications, altered and prolonged deliveries, etc.), which affect not only to the mother and can determine the health of the future human being. According to the scientific literature and based on an epigenetic effect, the intrauterine environment can be a determining aspect in the health of the future human being and the prevention of complications and pathologies (cardiovascular, metabolic, psychic, emotional). This is demonstrated by numerous and recent scientific evidences that confirm the unfortunate association between an adverse intrauterine environment (due to various factors) and different pathologies during and after pregnancy. It is evident the change that COVID-19 and its effects will generate in the lifestyle of the pregnant population and the increased probability of suffering associated pathologies in the next 24-36 months. No preventive actions have yet been planned in Spain and its public hospitals against the impact of COVID-19 on the quality of life of pregnant women. It is urgent to design and perform an adequate strategy of intervention for its possible prevention. From the scientific point of view, the recommendations are clear and concrete, an aerobic exercise program, designed and supervised by professionals from the Sciences of Physical Activity and Sports, is the best option for pregnant women. In this sense, in the last 30 years, physical exercise has proven to have many benefits for pregnant women, without causing risks or adverse effects on maternal-fetal well-being. This is confirmed by an important body of scientific literature on gestational physical exercise and its effects on pregnancy outcomes.

NCT04563065
Conditions
  1. Pregnancy Complications
  2. Pregnancy, High Risk
  3. Pregnancy Induced Hypertension
  4. Newborn Morbidity
  5. Fetal Growth Retardation
  6. Fetus Disorder
  7. Weight Gain, Maternal
  8. Maternal-Fetal Relations
Interventions
  1. Other: Exercise program
  2. Other: Healthy lifestyle advise
MeSH:Pregnancy Complications Fetal Growth Retardation Hypertension, Pregnancy-Induced Weight Gain Gestational Weight Gain
HPO:Increased body weight Intrauterine growth retardation

Primary Outcomes

Description: analyze the increase during pregnancy

Measure: Maternal weight gain

Time: 9 months

Description: analyze how it varies during pregnancy

Measure: blood pressure

Time: 9 months

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: OGTT-O'Sullivan test

Time: 1 month

Description: analyze with a questionnaire the value and its interrelationship with physical exercise patterns

Measure: Urinary Incontinence Questionnaire (ICIQ-SF)

Time: 9 months

Description: analyze with a questionnaire the variability during pregnancy

Measure: depression scale (CES-D)

Time: 9 months

Description: analyze variability during pregnancy

Measure: Behavior of Fetal Heart Rate

Time: 3 months

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: gestational age

Time: 9 months

Description: analyze whether women have had a vaginal, instrumental or cesarean delivery and its interrelationship with physical exercise patterns

Measure: type of delivery (Vaginal, instrumental or cesarean)

Time: 1 month

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: duration of labor

Time: 1 month

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: birthweight

Time: 1 month

Description: analyze the value and its interrelationship with physical exercise patterns during pregnancy

Measure: child's weight

Time: 24 months

Description: analyze the value and its interrelationship with physical exercise patterns during pregnancy

Measure: child's height

Time: 24 months

Description: analyze the value and its interrelationship with physical exercise patterns during pregnancy

Measure: mental assessment of the child (depression questionnaire adapted to childhood)

Time: 24 months

Secondary Outcomes

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: Maternal pains during pregnancy (headache, back pain, pelvic pain, paravertebral, scapular, etc.)

Time: 9 months

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: fetal growth and development

Time: 9 months

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: Delivery tears

Time: 1 month

Description: analyze the appearance (descriptive: yes/no) and its interrelationship with physical exercise patterns

Measure: performing episiotomy during childbirth

Time: 1 month

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: Apgar Score

Time: 1 month

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: length

Time: 1 month

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: cranial perimeter

Time: 1 month

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: Landau reflexes test

Time: 1 month

Description: analyze the number of admissions and its interrelationship with physical exercise patterns

Measure: neonatal intensive care unit (NICU)

Time: 1 month

Description: analyze how it varies during postpartum period

Measure: Postpartum recovery of pre-pregnancy weight

Time: 12 months

Description: analyze with a questionnaire how it varies during postpartum period

Measure: Edinburgh Postpartum Depression Scale (EPDS)

Time: 12 months

Other Outcomes

Description: analyze the value and its interrelationship with physical exercise patterns

Measure: Perception of health status - SF36 health scale

Time: 24 months

Description: analyze the diameter and thickness of muscles in the perineal area and its interrelationship with physical exercise patterns

Measure: Recovery of pelvic floor muscles ultrasound

Time: 6 months

Description: analyzewith a questionnaire how it varies during and after pregnancy

Measure: Maternal habits of physical activity - Pregnancy Physical Activity Questionnaire (PPAQ)

Time: 12 months

HPO Nodes


HP:0001511: Intrauterine growth retardation
Genes 609
SMARCAL1 CTBP1 BCS1L FMR1 MPLKIP PDX1 INSR PDX1 NEK9 HYMAI FANCL ARID1B TSFM ND2 KLF11 KCNJ11 COG7 KCNJ11 FOXH1 BRIP1 DDX11 POLE ATR DYNC2LI1 WRAP53 SMC1A STAT3 KIF14 TTC37 FGFRL1 FUT8 ALDH18A1 MTRR ORC6 PNPT1 WDR4 RNASEH2A HADH TERT DYRK1A NFIX TTC7A NSDHL NDUFS3 SOX11 KANSL1 NDUFAF8 NUP133 NDUFV2 NCAPG2 ATP7A ERCC8 ATP5F1A PIEZO2 EVC PHGDH TELO2 HMGA2 NDUFB11 HDAC6 FAM111A SDHB ORC6 GATA4 INS NDUFB11 KMT2A PLK4 RNF113A SMARCA2 SLC35A2 TFAP2A CEP57 PTCH1 XRCC4 SRCAP CHRND GATAD2B PIEZO2 PDSS2 CKAP2L GINS1 ESCO2 SFXN4 SLX4 FGFR1 FLI1 ESCO2 NUP107 TOP3A INSR TIMMDC1 NDUFAF8 NDUFB10 SIX3 GAS1 TMEM70 CHRNG FANCB SMARCB1 PLAGL1 CDKN1C SNRPB AFF2 RAD21 UNC80 MCTP2 CORIN BUB3 COQ4 SOX11 EMG1 ARVCF GFM2 EXOSC9 CKAP2L FANCA RERE UQCC2 H19-ICR KLHL7 TGIF1 MAPK1 GCK FANCI CTU2 NDUFS6 DONSON IGHMBP2 FOXRED1 RAB18 PHGDH SLC18A3 XPR1 TAF1 EVC2 XRCC2 TBC1D20 UBR1 NDUFAF4 ABCC8 WNT4 B3GLCT NKX2-5 PDGFRB HYMAI ZFPM2 TRAPPC11 FGF8 BCAP31 LEMD3 UBE2T DHDDS GATA6 TINF2 COQ9 SMC1A LMNA UFD1 LETM1 TMEM216 STAG1 NDUFS8 SDHD NDUFAF3 FANCB TDGF1 TMEM126B CTC1 MYH3 GPKOW RBM10 RPL10 TBCE RBM10 SEC61A1 CEP57 FANCM ERCC4 SDHAF1 FLNB TBX1 CHRNG ERCC6 KIF2A RAF1 ZMPSTE24 CLCN7 CCNQ DHCR24 ABCC8 STN1 NDUFAF5 LFNG NSD2 ITPA PTPN11 SIN3A CUL7 ATP7A GCK COG6 PDE6D ERCC2 COMT PLK4 BCS1L GMNN DOK7 ZFP57 SKIV2L JMJD1C GLIS3 FANCL SMAD4 TMEM70 ERCC3 NDUFS2 PKLR NEUROD1 NDUFV1 PEX5 PCGF2 TFAM ATP6V0A2 OSGEP GTPBP3 HIRA DKC1 BCR BRCA2 NELFA PTDSS1 CPLX1 NSUN2 OTUD6B CITED2 DNAJC21 PIK3R1 ACD BRCA1 FKTN BUB1B PYCR1 RERE HOXD13 TERT SOX4 NSD2 GATA5 TARS1 MKS1 FLVCR2 PEX2 SIX2 ELN MAD2L2 ZMPSTE24 PAX4 SLC25A24 ALX4 PLK4 KDM6A GATA4 NDUFAF2 TUBGCP6 GATA6 RTEL1 LARS2 VPS13B PLAGL1 RNU4ATAC ARID1A NODAL TALDO1 HDAC6 HNF1A NDUFA10 TCTN3 BRAF STRA6 SMARCE1 POLR3A CDC45 STRA6 NODAL CDC6 TBX1 HNF4A NDUFB3 POLA1 BUB1 PPP1R15B KMT2A RFWD3 CEP290 BLM STOX1 ABL1 ATR TRAIP PDE4D ARID2 XYLT1 SEC24C CDKN1C IARS1 IGF1R ERCC5 NUS1 TAPT1 FTO GCK DLL1 ALG8 CTC1 HSD11B2 RB1 CDC6 SON STT3B POLR3A DNMT3A HDAC8 BRCA2 PALB2 NDUFS7 NUP88 P4HB ABCB7 RIPPLY2 CCDC8 ACD IGF1R FANCE NALCN RNU4ATAC DHCR7 RAB3GAP1 GDF1 NDUFAF5 PHGDH RTTN SMARCC2 ABCC8 SC5D CEP152 NOP10 RFWD3 PSAT1 SMARCD1 HES7 NUP188 POLA1 NIN TFAP2A ND3 HHAT ZNF335 RAB3GAP2 QRICH1 TTC7A CDON RNU4ATAC NIPBL SAMD9 COG4 B3GLCT GTF2H5 GLI3 ERCC1 INSR CENPE YY1 TUFM WARS2 MBTPS2 RREB1 BLK SEMA3E LAGE3 FANCF COQ2 STT3B PAH TUBGCP4 PIGG CHD7 TRIP13 WASHC5 MESP2 CNOT1 SLC26A2 SMC3 GTF2E2 PRKDC ZIC2 NDUFS1 ALDH18A1 PDGFB TRMT10A MYORG BLM TTC37 MCM4 TBCE FANCG NIPBL SEMA5A IGF1 DONSON YY1 TCTN3 PRKAR1A ASXL1 COG1 COQ7 MLXIPL ZFP57 KCNJ11 ADGRG6 KCNJ11 FLT1 SMARCB1 RECQL4 FLT4 LETM1 KIF5C INS FANCI IGF1 SLC25A24 FANCD2 ORC1 TPRKB DISP1 MCM5 ERCC5 JAG1 RIPK4 LIFR POLE OBSL1 ATP6V0A2 PCNT RTEL1 ND1 SMARCA4 NIN SIN3A ASXL1 SF3B4 TBX4 UBR1 ABCC8 PLOD3 GP1BB SLC25A13 PSAT1 NDUFB3 ERCC1 NDUFAF4 NKX2-6 DPF2 RAPSN CENPE ARID1B RAD51 ATP6V1A PCNT PCNT ADAT3 ATP6V0A2 LIG4 WNT7A SDHA ERCC6 CENPJ BMPER PSPH RTEL1 PPP1R15B HYLS1 MUSK DHCR7 RNF113A PDE4D UNC80 ESCO2 ATRIP RNU4ATAC CRKL SHH COG5 NPM1 NDUFA6 FAM20C NDUFA6 INS PCDH12 UQCRFS1 IBA57 SKIV2L TBX6 TINF2 DKC1 SMC1A CENPJ GBA CDCA7 RAD51C PUF60 GLI1 NDUFS4 DNAJC19 CTNND2 RARB ORC4 GLI2 BRPF1 SEC24D ALG1 NDUFA1 ARCN1 ERCC2 CDKN1C ORC4 TBX1 WDR73 DLL3 NDUFA11 TERC ORC1 WDR4 SETD5 OTUD6B PDX1 CHRNA1 TRAIP TP53RK SMARCAL1 APPL1 MYOD1 PRPS1 CTDP1 NDUFAF1 TINF2 CUL7 FIG4 GLI3 FANCC GFM1 WHCR SMARCE1 PDE4D DNAJC19 PARN INS ERCC2 ARL6IP6 TRIM37 CDT1 FBN1 TGDS RBBP8 IGF2 TBCE CEL GJA5 BRIP1 GATA6 RFX6 SLC20A2 CDK10 SMARCA4 NDUFB9 ATP6V1E1 NHP2 MUSK LMNA NBN NDE1 PARN CDT1 SUFU EIF2AK3 PSAT1 HYMAI SMAD4 USB1 BUB1B RPL11 IFIH1 PDX1 PIGG AARS1 RPS19 TBCE GTF2E2 LAGE3 DKC1 JAM2 TINF2 WDR73 FGFR1 NOS3 OSGEP NUBPL PARN
Protein Mutations 1
G20210A
SNP 0

HPO

Alphabetical listing of all HPO terms. Navigate: Correlations   Clinical Trials


HPO Nodes


HP:0001511: Intrauterine growth retardation
Genes 609
SMARCAL1 CTBP1 BCS1L FMR1 MPLKIP PDX1 INSR PDX1 NEK9 HYMAI FANCL ARID1B TSFM ND2 KLF11 KCNJ11 COG7 KCNJ11 FOXH1 BRIP1 DDX11 POLE ATR DYNC2LI1 WRAP53 SMC1A STAT3 KIF14 TTC37 FGFRL1 FUT8 ALDH18A1 MTRR ORC6 PNPT1 WDR4 RNASEH2A HADH TERT DYRK1A NFIX TTC7A NSDHL NDUFS3 SOX11 KANSL1 NDUFAF8 NUP133 NDUFV2 NCAPG2 ATP7A ERCC8 ATP5F1A PIEZO2 EVC PHGDH TELO2 HMGA2 NDUFB11 HDAC6 FAM111A SDHB ORC6 GATA4 INS NDUFB11 KMT2A PLK4 RNF113A SMARCA2 SLC35A2 TFAP2A CEP57 PTCH1 XRCC4 SRCAP CHRND GATAD2B PIEZO2 PDSS2 CKAP2L GINS1 ESCO2 SFXN4 SLX4 FGFR1 FLI1 ESCO2 NUP107 TOP3A INSR TIMMDC1 NDUFAF8 NDUFB10 SIX3 GAS1 TMEM70 CHRNG FANCB SMARCB1 PLAGL1 CDKN1C SNRPB AFF2 RAD21 UNC80 MCTP2 CORIN BUB3 COQ4 SOX11 EMG1 ARVCF GFM2 EXOSC9 CKAP2L FANCA RERE UQCC2 H19-ICR KLHL7 TGIF1 MAPK1 GCK FANCI CTU2 NDUFS6 DONSON IGHMBP2 FOXRED1 RAB18 PHGDH SLC18A3 XPR1 TAF1 EVC2 XRCC2 TBC1D20 UBR1 NDUFAF4 ABCC8 WNT4 B3GLCT NKX2-5 PDGFRB HYMAI ZFPM2 TRAPPC11 FGF8 BCAP31 LEMD3 UBE2T DHDDS GATA6 TINF2 COQ9 SMC1A LMNA UFD1 LETM1 TMEM216 STAG1 NDUFS8 SDHD NDUFAF3 FANCB TDGF1 TMEM126B CTC1 MYH3 GPKOW RBM10 RPL10 TBCE RBM10 SEC61A1 CEP57 FANCM ERCC4 SDHAF1 FLNB TBX1 CHRNG ERCC6 KIF2A RAF1 ZMPSTE24 CLCN7 CCNQ DHCR24 ABCC8 STN1 NDUFAF5 LFNG NSD2 ITPA PTPN11 SIN3A CUL7 ATP7A GCK COG6 PDE6D ERCC2 COMT PLK4 BCS1L GMNN DOK7 ZFP57 SKIV2L JMJD1C GLIS3 FANCL SMAD4 TMEM70 ERCC3 NDUFS2 PKLR NEUROD1 NDUFV1 PEX5 PCGF2 TFAM ATP6V0A2 OSGEP GTPBP3 HIRA DKC1 BCR BRCA2 NELFA PTDSS1 CPLX1 NSUN2 OTUD6B CITED2 DNAJC21 PIK3R1 ACD BRCA1 FKTN BUB1B PYCR1 RERE HOXD13 TERT SOX4 NSD2 GATA5 TARS1 MKS1 FLVCR2 PEX2 SIX2 ELN MAD2L2 ZMPSTE24 PAX4 SLC25A24 ALX4 PLK4 KDM6A GATA4 NDUFAF2 TUBGCP6 GATA6 RTEL1 LARS2 VPS13B PLAGL1 RNU4ATAC ARID1A NODAL TALDO1 HDAC6 HNF1A NDUFA10 TCTN3 BRAF STRA6 SMARCE1 POLR3A CDC45 STRA6 NODAL CDC6 TBX1 HNF4A NDUFB3 POLA1 BUB1 PPP1R15B KMT2A RFWD3 CEP290 BLM STOX1 ABL1 ATR TRAIP PDE4D ARID2 XYLT1 SEC24C CDKN1C IARS1 IGF1R ERCC5 NUS1 TAPT1 FTO GCK DLL1 ALG8 CTC1 HSD11B2 RB1 CDC6 SON STT3B POLR3A DNMT3A HDAC8 BRCA2 PALB2 NDUFS7 NUP88 P4HB ABCB7 RIPPLY2 CCDC8 ACD IGF1R FANCE NALCN RNU4ATAC DHCR7 RAB3GAP1 GDF1 NDUFAF5 PHGDH RTTN SMARCC2 ABCC8 SC5D CEP152 NOP10 RFWD3 PSAT1 SMARCD1 HES7 NUP188 POLA1 NIN TFAP2A ND3 HHAT ZNF335 RAB3GAP2 QRICH1 TTC7A CDON RNU4ATAC NIPBL SAMD9 COG4 B3GLCT GTF2H5 GLI3 ERCC1 INSR CENPE YY1 TUFM WARS2 MBTPS2 RREB1 BLK SEMA3E LAGE3 FANCF COQ2 STT3B PAH TUBGCP4 PIGG CHD7 TRIP13 WASHC5 MESP2 CNOT1 SLC26A2 SMC3 GTF2E2 PRKDC ZIC2 NDUFS1 ALDH18A1 PDGFB TRMT10A MYORG BLM TTC37 MCM4 TBCE FANCG NIPBL SEMA5A IGF1 DONSON YY1 TCTN3 PRKAR1A ASXL1 COG1 COQ7 MLXIPL ZFP57 KCNJ11 ADGRG6 KCNJ11 FLT1 SMARCB1 RECQL4 FLT4 LETM1 KIF5C INS FANCI IGF1 SLC25A24 FANCD2 ORC1 TPRKB DISP1 MCM5 ERCC5 JAG1 RIPK4 LIFR POLE OBSL1 ATP6V0A2 PCNT RTEL1 ND1 SMARCA4 NIN SIN3A ASXL1 SF3B4 TBX4 UBR1 ABCC8 PLOD3 GP1BB SLC25A13 PSAT1 NDUFB3 ERCC1 NDUFAF4 NKX2-6 DPF2 RAPSN CENPE ARID1B RAD51 ATP6V1A PCNT PCNT ADAT3 ATP6V0A2 LIG4 WNT7A SDHA ERCC6 CENPJ BMPER PSPH RTEL1 PPP1R15B HYLS1 MUSK DHCR7 RNF113A PDE4D UNC80 ESCO2 ATRIP RNU4ATAC CRKL SHH COG5 NPM1 NDUFA6 FAM20C NDUFA6 INS PCDH12 UQCRFS1 IBA57 SKIV2L TBX6 TINF2 DKC1 SMC1A CENPJ GBA CDCA7 RAD51C PUF60 GLI1 NDUFS4 DNAJC19 CTNND2 RARB ORC4 GLI2 BRPF1 SEC24D ALG1 NDUFA1 ARCN1 ERCC2 CDKN1C ORC4 TBX1 WDR73 DLL3 NDUFA11 TERC ORC1 WDR4 SETD5 OTUD6B PDX1 CHRNA1 TRAIP TP53RK SMARCAL1 APPL1 MYOD1 PRPS1 CTDP1 NDUFAF1 TINF2 CUL7 FIG4 GLI3 FANCC GFM1 WHCR SMARCE1 PDE4D DNAJC19 PARN INS ERCC2 ARL6IP6 TRIM37 CDT1 FBN1 TGDS RBBP8 IGF2 TBCE CEL GJA5 BRIP1 GATA6 RFX6 SLC20A2 CDK10 SMARCA4 NDUFB9 ATP6V1E1 NHP2 MUSK LMNA NBN NDE1 PARN CDT1 SUFU EIF2AK3 PSAT1 HYMAI SMAD4 USB1 BUB1B RPL11 IFIH1 PDX1 PIGG AARS1 RPS19 TBCE GTF2E2 LAGE3 DKC1 JAM2 TINF2 WDR73 FGFR1 NOS3 OSGEP NUBPL PARN
Protein Mutations 1
G20210A
SNP 0

Reports

Data processed on September 26, 2020.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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