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D004775: Enuresis

Developed by Shray Alag, The Harker School
Sections: Correlations, Clinical Trials, and HPO

Correlations computed by analyzing all clinical trials.

Navigate: Clinical Trials and HPO


Correlated Drug Terms (2)


Name (Synonyms) Correlation
drug3593 Urinary Incontinence Wiki 1.00
drug3061 Sedentary behaviour Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D014549 Urinary Incontinence NIH 1.00

Correlated HPO Terms (2)


Name (Synonyms) Correlation
HP:0000805 Enuresis HPO 1.00
HP:0000020 Urinary incontinence HPO 1.00

Clinical Trials

Navigate: Correlations   HPO

There is one clinical trial.


1 Associations Between Urinary Incontinence, Sedentary Behaviour and Other Health-related Outcomes in Nursing Homes in Catalonia: the OsoNaH Project

The increase of the older adult population in the past years has generated an important impact on chronic conditions and geriatric syndromes like dementia, falls and urinary incontinence (UI). To better understand IU seems warranted because of its socioeconomic and health impact. Nursing home (NH) residents are the frailest segment of our population, with very low physical activity levels and highly sedentary. Several studies had shown that physical activity levels and time and patterns of sedentary behaviour (SB) are independent risk factors for many health issues. As far as the investigators know, there is no evidence supporting the relation between IU and SB, and no information about the incidence of IU in NH residents living in Catalonia (Spain). This project consists of two stages: stage 1 will conduct a cross-sectional study using mixed methodology (qualitative and quantitative), and a 2-year longitudinal study (stage 2). Stage 1 has the main objective of verifying the prevalence of IU and its associated factors in NH residents in Barcelona (Spain), as well as analyse the association between IU (and their types) with SB time and patterns. In addition, the proportion of geriatric residents who receive control measures for their IU, and whether they receive SB-related interventions from health professionals of the institution will be also explored. Finally, the investigators aim to understand the experience of NH residents and the health professionals who care for them about the characteristics, burden and barriers of having IU. Stage 2 has the main objective to verify the incidence of the functional and continence decline, falls, hospitalizations and mortality, as well as their predictive factors in older care/nursing home residents in Barcelona (Spain). Specific objetives are to assess the evolution of each activity of daily living and the causes of hospitalization and death in geriatrics residents for a period of 2 years and to verify the incidence of recurrent falls (one or more falls), and analyse the consequences of falls (fractures, hospitalizations, among others) among the residents. Potential risk and protective factors for mortality due to COVID-19 and its impact on functioning and hospitalizations will also be analyzed. Finally, the stage 2 of the project aims at creating a specific instrument for the evaluation of frailty in institutionalized older people, based on the main predictive factors of functional decline.

NCT04297904
Conditions
  1. Urinary Incontinence in Old Age
  2. Sedentary Behavior
Interventions
  1. Behavioral: Sedentary behaviour
  2. Diagnostic Test: Urinary Incontinence
MeSH:Urinary Incontinence Enuresis
HPO:Enuresis Urinary incontinence

Primary Outcomes

Description: The presence of IU assessed by the Minimum Data Set (MDS) version 3.0

Measure: Urinary Incontinence

Time: January 2020 to July 2020 (cross-sectional)

Description: Patterns of sedentary behaviour (SB) with monitors (PAL Technologies, Scotland).

Measure: Patterns of sedentary behaviour

Time: January 2020 to July 2020 (cross-sectional)

Description: Modified (Likert 5-point scale) Barthel Index, assessed every 6 months

Measure: Functional decline

Time: January 2020 to January 2022 (longitudinal, follow-up)

Description: Minimum Data Set (MDS) version 3.0, assessed every 6 months

Measure: Continence decline

Time: January 2020 to January 2022 (longitudinal, follow-up)

Description: Prospective register of falls (date, place and consequence/s)

Measure: Incidence of falls

Time: January 2020 to January 2022 (longitudinal, follow-up)

Description: Prospective register of hospitalizations (date and cause)

Measure: Hospitalizations

Time: January 2020 to January 2022 (longitudinal, follow-up)

Description: Prospective register of deaths (date and cause)

Measure: Mortality

Time: January 2020 to January 2022 (longitudinal, follow-up)

Secondary Outcomes

Description: Sociodemographic variables (sex, age, civil status, education level, type of institution (public versus private / concerted) and time of residence in the institution.)

Measure: Sociodemographic variables

Time: January 2020 to July 2020

Description: Number and proportion of participants with lower urinary tract symptoms with the International Prostate Symptoms Score and urinary infection for the last 30 days.

Measure: Lower urinary tract symptoms

Time: January 2020 to July 2020

Description: Faecal incontinence according to Minimum Data Set version 3.0 (MDS 3.0)

Measure: Faecal incontinence

Time: January 2020 to July 2020

Description: Diary

Measure: Intake of liquids and diuretic drinks

Time: January 2020 to July 2020

Description: Dynamometer (2 trials per hand)

Measure: Handgrip strength

Time: January 2020 to July 2020

Description: Short Physical Performance Battery (SPPB)

Measure: Physical performance

Time: January 2020 to July 2020

Description: Rivermead Mobility Index

Measure: Mobility

Time: January 2020 to July 2020

Description: Clinical Frailty Scale

Measure: Frailty

Time: January 2020 to July 2020

Description: Modified (Likert 5-point scale) Barthel Index

Measure: Basic activities of daily living

Time: January 2020 to July 2020

Description: What kind of physical activity programme, the frequency of the sessions weekly, the dose of exercise of each session, the duration of the whole session, who provides the session, where the session is performed and if the session is individually or in group).

Measure: Physical activity programs

Time: January 2020 to July 2020

Description: What kind of programs are being applied to control and treat urinary and faecal incontinence in nursing homes

Measure: Incontinence programs

Time: January 2020 to July 2020

Description: According to the Anatomical Therapeutic Chemical classification system and the Defined Daily Dose (ATC/DDD)

Measure: Medication intake

Time: January 2020 to July 2020

Description: Number and proportion of participants with chronic diseases, delirium and pressure ulcers

Measure: Health conditions

Time: January 2020 to July 2020

Description: European Quality of Life-5 Dimensions; final score for Spain ranges between 1 (full health) to -0.654 (worse outcome)

Measure: Quality of life

Time: January 2020 to July 2020

Description: smoking and alcohol

Measure: Toxic habits

Time: January 2020 to July 2020

Description: Pfeiffer Scale, with final score ranging from 0 (normal) to 10 (total cognitive impairment)

Measure: Cognitive status

Time: January 2020 to July 2020

Description: 15-item Yesavage Geriatric Depression Scale, with final score ranging from 0 (normal) to 15 (severe depression)

Measure: Depressive symptoms

Time: January 2020 to July 2020

Description: Hospital Anxiety and Depression Scale (HADS), with final score ranging from 0 (normal) to 21 (severe anxiety)

Measure: Anxiety

Time: January 2020 to July 2020

Description: Using the NH register

Measure: Number births

Time: January 2020 to July 2020

Description: Using the NH register

Measure: Type of births

Time: January 2020 to July 2020

Description: During the last year, according to the NH register

Measure: Number of falls

Time: January 2020 to July 2020

Description: Mini Nutritional Assessment Test, ranging from 0 (malnutrition) to 30 (normal)

Measure: Nutritional status

Time: January 2020 to July 2020

Description: Amount of Vitamin D, albumin and pre-albumin, PCR (Protein C-Reactive) extracted from the routine analysis of the residents.

Measure: Biochemical evaluation

Time: January 2020 to July 2020

Description: Percentage (%) of body fat, % of fat-free mass and % of body water assessed by a Tanita TBF-300 bioimpedance device

Measure: Body composition

Time: January 2020 to July 2020

Description: Lubben Social Network Scale ranging from 0 to 30, with a higher score indicating more social engagement.

Measure: Social network

Time: January 2020 to July 2020

Description: 6-item Gierveld Loneliness Scale ranging from 0 (not lonely) to 6

Measure: Loneliness

Time: January 2020 to July 2020

Description: Date and result of diagnosis test/s for COVID-19 (PCR or serological antibody test)

Measure: COVID-19

Time: June 2020 to January 2022 (longitudinal, follow-up)

Description: In the previous 6 months, the resident had symptoms compatible with COVID-19 (cough, fever and/or breathing difficulties) without COVID-19 diagnosis test confirmation

Measure: Suspected case of COVID-19

Time: June 2020 to January 2022 (longitudinal, follow-up)

Description: Level of resident's frailty assessed with the Clinical Frailty Scale

Measure: Frailty

Time: June 2020 to January 2022 (longitudinal, follow-up)

Description: Any change in the regular medication in the last 6 months (include the name of the med, dose and the duration of treatment)

Measure: Change in medication

Time: June 2020 to January 2022 (longitudinal, follow-up)

HPO Nodes


Reports

Data processed on September 26, 2020.

An HTML report was created for each of the unique drugs, MeSH, and HPO terms associated with COVID-19 clinical trials. Each report contains a list of either the drug, the MeSH terms, or the HPO terms. All of the terms in a category are displayed on the left-hand side of the report to enable easy navigation, and the reports contain a list of correlated drugs, MeSH, and HPO terms. Further, all reports contain the details of the clinical trials in which the term is referenced. Every clinical trial report shows the mapped HPO and MeSH terms, which are also hyperlinked. Related HPO terms, with their associated genes, protein mutations, and SNPs are also referenced in the report.

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