SNPMiner Trials by Shray Alag

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SNPMiner SNPMiner Trials (Home Page)


Report for Mutation L28P

Developed by Shray Alag, 2020.
SNP Clinical Trial Gene

There is one clinical trial.

Clinical Trials


1 Creation and Evaluation of the Effectiveness of the Remote Monitoring System for Patients, Who Had Myocardial Infarction

one-centered, open, prospective, non-randomized, controlled clinical study will be aimed at creating remote monitoring system for patients' condition and the development of methodological approaches and its usage for conducting patients, who had myocardial infraction and who has a very high risk of developing an unfavorable outcome.

NCT04424368
Conditions
  1. Myocardial Infarction
  2. Adherence, Patient
Interventions
  1. Device: The remote monitoring system
MeSH:Myocardial Infarction Infarction
HPO:Myocardial infarction

At the end of a 12 month observation with the registration of unfavorable cardiovascular occasions (death from cardiovascular reasons, nonfatal myocardial infraction, cerebral stroke, necessity for repeated revascularization of the coronary arteries) based on the analysis of non-genetic and genetic factors (polymorphism of genes Thr174Met and Met235Thr in gene angiotensinogen, Arg389Gly and Ser49Gly in gene adrenoceptor beta 1, Ser447Ter in gene lipoprotein lipase and Leu28Pro in gene apolipoprotein E, Trp212Ter and G681A in gene cytochrome P450 family 2 subfamily C member 19) factors of unfavorable prognosis will be identified and considering which group of patients requires the use of remote monitoring system will be formed. --- Thr174Met --- --- Met235Thr --- --- Arg389Gly --- --- Ser49Gly --- --- Leu28Pro ---

Primary Outcomes

Description: the number of deaths from cardiovascular causes

Measure: cardiovascular mortality

Time: 12 months

Description: incidence of acute myocardial infarction

Measure: acute myocardial infarction

Time: 12 months

Description: incidence of cerebral stroke

Measure: cerebral stroke

Time: 12 months

Description: frequency of repeated revascularization of coronary arteries

Measure: revascularization

Time: 12 months

Description: frequency of hospitalization about the progression of coronary heart disease

Measure: hospitalization

Time: 12 months


HPO Nodes