CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


this study is non- interventionalWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (1)


Name (Synonyms) Correlation
drug563 Non-Interventional Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D018352 Coronavirus Infections NIH 0.06

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Clinical and Immunological Characterisation of COVID-19 in Children, Adolescents and Adults

The investigators aim to characterise Coronavirus Disease 2019 (COVID-19) in every age group. On the one hand, emphasis is put on the initial presentation, clinical course, outcome and the therapy used. On the other hand further investigations regarding viral and bacterial coinfections, and response of the immune system will be conducted. This study should serve to improve the understanding of COVID-19, to identify risk factors for a severe clinical course and to obtain further insights into pathophysiology of this new infectious disease.

NCT04341168 COVID-19 SARS-CoV-2 Other: this study is non- interventional

Primary Outcomes

Description: Description of clinical course of COVID-19 in children, adolescents and adults

Measure: Clinical course of COVID-19

Time: 10/2020

Description: Measurement of specific IgM- and IgG-antibody production

Measure: Analysis of development of antibodies to SARS-CoV-2

Time: 10/2020

Description: Estimation of viral load at initial presentation and after two weeks

Measure: Estimation of viral load

Time: 10/2020

Description: A Multiplex PCR will be conducted to test for the most common respiratroy viruses. A naso- and oropharyngeal swab will be used for this

Measure: Detection of viral coinfections

Time: 10/2020

Description: Determination of cytokine and chemokine concentrations in serum by ELISA.

Measure: Measurement of cytokine and chemokine response

Time: 12/2020

Description: Characterisation of virus-host-interaction by HLA-typing

Measure: Characterisation of virus-host-interaction

Time: 12/2020

Description: Identification of disease patterns in proteome by analysis of the proteome in serum and urine

Measure: Identification of disease patterns in proteome

Time: 12/2020

Description: Detection of change in lymphocyte subtypes in blood and bronchoalveolar lavage

Measure: Analysis of change in lymphocyte subtypes

Time: 10/2020

Description: Analysis of histological changes in severe lung disease by lung biopsy

Measure: Analysis of histological changes in severe lung disease

Time: 12/2020

Description: A pharyngeal swab will be cultured to check for bacteria residing in the upper airways. Additionally, a blood culture will serve to detect bacteremia

Measure: Detection of bacterial coinfections

Time: 10/2020


No related HPO nodes (Using clinical trials)