Name (Synonyms) | Correlation | |
---|---|---|
drug113 | Best Practice Wiki | 1.00 |
drug393 | Hydroxychloroquine in combination of Azithromycin Wiki | 1.00 |
drug854 | Tocilizumab Wiki | 0.25 |
Name (Synonyms) | Correlation | |
---|---|---|
D007676 | Kidney Failure, Chronic NIH | 1.00 |
D020521 | Stroke NIH | 0.71 |
D003324 | Coronary Artery Disease NIH | 0.71 |
D029424 | Pulmonary Disease, Chronic Obstructive NIH | 0.58 |
D008173 | Lung Diseases, Obstructive NIH | 0.50 |
D009369 | Neoplasms, NIH | 0.38 |
D007239 | Infection NIH | 0.08 |
Name (Synonyms) | Correlation |
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There is one clinical trial.
Patients with COVID-19 which are 60 years old or above or with comorbidities are at risk of deteriorating and developing severe illness. This prospective open label study will include people 60 years old or above or younger if at risk for severe disease. Individuals confirmed to have SARS-CoV-2 infection will be identified using medical records screening. They will then be offered to participate in the study and if agree will be given the informed consent. After examining inclusion and exclusion criteria they will be asked to sign the informed consent and after signing Information like immunizations, ECG results, diagnostic images and reports, written medical reports, diagnostic lab testing results (e.g. blood tests, urine tests, blood bank info), allergies and intolerances (drug and food allergies, food intolerances), prescription history, and general patient information (e.g. name, birthdate, personal health number, address, phone number) will be gathered. Those who are not eligible for the study will be informed of the reason(s) for ineligibility (generally it will be a safety exclusion and they should be aware of this). Those who are eligible will be randomized to one of three arms: hydroxychloroquine + azithromycin, hydroxychloroquine + camostat mesylate or "doing nothing" in a ratio of 2:1:2. Study drug will be dispensed by the hospital pharmacy. Follow up will continue for 8 weeks.
Description: the clinical state of the patient regarding respiratory state as defined by the NEWS scoring system
Measure: clinical state as reflected by NEWS scoring Time: 7 daysDescription: positive PCR SARS COVID 2 in the respiratory system
Measure: positive PCR Time: 7 daysDescription: prevention of hospitaliztion in the ICU
Measure: prevention of ICU Time: 14 daysDescription: prevention of assisted ventilation
Measure: prevention of assisted ventilation Time: 14 daysDescription: prevention of Extracorporeal Membrane Oxygenation (ECMO)
Measure: prevention of ECMO Time: 14 daysDescription: death
Measure: death Time: 14 daysDescription: positive PCR SARS COVID 2 in the respiratory system
Measure: positive PCR Time: 14 daysDescription: death
Measure: death Time: 60 days