Name (Synonyms) | Correlation | |
---|---|---|
drug386 | Hydroxychloroquine Sulfate Regular dose Wiki | 0.71 |
drug385 | Hydroxychloroquine Sulfate Loading Dose Wiki | 0.71 |
drug190 | Chloroquine Wiki | 0.41 |
drug616 | Placebo Wiki | 0.10 |
Name (Synonyms) | Correlation | |
---|---|---|
D058070 | Asymptomatic Diseases NIH | 0.71 |
D045169 | Severe Acute Respiratory Syndrome NIH | 0.07 |
D018352 | Coronavirus Infections NIH | 0.06 |
Name (Synonyms) | Correlation |
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There is one clinical trial.
The trial will be done to determine the impact of a barrier enclosure, COVID (coronavirus disease -19) barrier box on endotracheal intubation attempts, and duration. This study will be a prospective, open-label, randomized controlled trial. A total of 100 patients scheduled for elective surgery will be randomly assigned in two groups (intervention group and control group). Participating attending anesthesiologists will intubate the intervention group patients with COVID barrier box and the control group patients without the box. The anesthesiologists and the intervention group patients will be surveyed about their perception after the surgery. The result of this study will help in decision making about using COVID barrier box to minimize the viral transmission from patients to healthcare workers during the pandemic.
Description: TTI is the time from when the laryngoscope blade passes between the patient's lips until the first upstroke of the capnograph trace. TTI will be measured by a third party observer outside of the operating room.
Measure: Time to tracheal intubation (TTI) Time: This will be measured at the time of intubation for an elective surgical patient. It will take approximately 5 minutes.Description: A first pass success refers to successful insertion of the McGRATH™ videolaryngoscope or endotracheal tube by an anesthesiologist on the first-attempt without withdrawing from the mouth in no longer than 150 seconds.
Measure: First pass success rate Time: This will be measured at the time of intubation for an elective surgical patient within 150 seconds of initiating the first attempt to intubate.Description: This refers to the time from the face mask seal being lifted to the first upstroke of the capnograph trace.
Measure: Total time of airway manipulation Time: This will be measured at the time of intubation for an elective surgical patient. It will take approximately 5 minutes.Description: Participant anesthesiologists will report the following: number of intubation attempts, number of operators present in the operating room, number of alternative techniques used for intubation (if any) i.e. repositioning of patient, change of materials (blade, endotracheal (ET) tube, addition of stylette), change in approach (nasotracheal vs orotracheal), use of another technique (Fibreoptic bronchoscopy, intubating laryngeal mask airway (LMA)), Cormack-Lehane Grade for the first attempt of intubation, if the lifting force applied on laryngoscope blade was normal or increased, if laryngeal pressure, such as Backward Upward Rightward Pressure (BURP) not inclusive of cricoid pressure was applied or not, vocal cord position (either abduction or adduction), difficulty experienced during the intubation from a scale of 0 to 10 with 0 being without difficulty and 10 being maximum difficulty, as well as if they experience any difficulties in intubation, and their overall narrative feedback
Measure: Anesthesiologist perception of intubation difficulty Time: This questionnaire will be filled in after intubation is completed. It will take approximately 10 minutes.Description: Patients from the intervention group will report the following: acceptability of COVID barrier box: on a five-point scale (acceptable, slightly acceptable, neutral, slightly unacceptable, unacceptable), comfort experienced with COVID barrier box: on a five-point scale (comfortable, slightly comfortable, neither, slightly uncomfortable, uncomfortable), and their narrative feedback on experience with COVID barrier box.
Measure: Patient satisfaction Time: This questionnaire will be administered to the patients when they meet the Post Anesthesia Care Unit (PACU) discharge criteria (usually 2 to 5 hours post surgery) before leaving PACU. It will take about 10 minutes to complete.