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drug824 | Telephone follow-up Wiki | 1.00 |
drug204 | Clinical examination Wiki | 1.00 |
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There is one clinical trial.
The Nancy Cov-H-AKI: study is a prospective, non-randomized, monocenter study performed in patients hospitalised for either the severe or the critical form of Covid-19. The main objective of the Nancy Cov-H-AKI study is to evaluate the association of variations (from inclusion to 72H post-inclusion) of 5 blood-based cardio-vascular-renal biomarkers selected a priori, cardiac (NT-proBNP), coagulation (D-dimers), related to the renin angiotensin aldosterone system (ACE2) and renal (Penkid, and NGAL) with the appearance of acute kidney injury KDIGO grade 1 or higher OR cardiac injury in patients hospitalised for either the severe or the critical form of Covid-19
Description: Composite endpoint : Worsening of renal function by at least KDIGO grade 1 criteria from inclusion visit OR troponin greater than 99th percentile during hospitalization for Covid-19 infection (with Outcome 2).
Measure: Worsening of renal function by at least KDIGO grade 1 during hospitalization for Covid-19 infection Time: From inclusion to hospital discharge, an average of 21 daysDescription: Composite endpoint : Worsening of renal function by at least KDIGO grade 1 criteria from inclusion visit OR troponin greater than 99th percentile during hospitalization for Covid-19 infection (with Outcome 1)
Measure: Troponin greater than 99th percentile during hospitalization for Covid-19 infection Time: From inclusion to hospital discharge, an average of 21 daysDescription: Composite endpoint : AKI KDIGO grade 1 or higher or Elevation of troponin> 99th percentile in hospitalisation (approach with AND without a priori) ((with Outcome 3 )
Measure: AKI KDIGO grade 1 or higher in hospitalisation (approach with AND without a priori) Time: From inclusion to hospital discharge, an average of 21 daysDescription: Composite endpoint : AKI KDIGO grade 1 or higher or Elevation of troponin> 99th percentile in hospitalisation (approach with AND without a priori) (with Outcome 3)
Measure: Elevation of troponin> 99th percentile in hospitalisation (approach with AND without a priori) Time: From inclusion to hospital discharge, an average of 21 daysDescription: AKI KDIGO grade 1 in hospitalisation
Measure: AKI KDIGO grade 1 or higher Time: From inclusion to hospital discharge, an average of 21 daysDescription: Association with troponin elevation >99th percentile during hospitalisation
Measure: Association with troponin elevation >99th Time: From inclusion to hospital discharge, an average of 21 daysDescription: Association with elevation of serum creatinine >30% during hospitalisation
Measure: Association with elevation of serum creatinine >30% Time: From inclusion to hospital discharge, an average of 21 daysDescription: With the onset of chronic renal failure (eDFG <60 ml / min / 1.73m2) three months after discharge from hospital
Measure: With the onset of chronic renal failure (eDFG <60 ml / min / 1.73m2) Time: 3 months after discharge from hospitalDescription: Composite outcome : the occurrence of cardiovascular events (stroke, myocardial infarction, hospitalisation for heart failure, cardiovascular death) and death from any cause during hospitalisation and three months after discharge from hospital
Measure: The occurrence of cardiovascular events (stroke, myocardial infarction, hospitalisation for heart failure, cardiovascular death) during hospitalisation and three months after discharge from hospital Time: From inclusion to three months after discharge from hospitalDescription: Composite outcome : the occurrence of cardiovascular events (stroke, myocardial infarction, hospitalisation for heart failure, cardiovascular death) and death from any cause during hospitalisation and three months after discharge from hospital
Measure: The occurrence of death from any cause during hospitalisation and three months after discharge from hospital Time: From inclusion to three months after discharge from hospital