CovidResearchTrials by Shray Alag


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Blood samples (collection of 5 mL of blood in a dry tube)Wiki

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There is one clinical trial.

Clinical Trials


1 COVID-19 Study of the Serological Response Against the SARS-CoV-2 Virus in 2 Types of Employees, Hospital and Non-hospital, at Institute Curie

This research proposes to study a large healthy population active for the presence of antibodies directed against the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus and this over time. After verification of the inclusion criteria and information by the coordinating investigative doctor, the volunteers sign a written consent. A nurse will take blood samples under safe conditions compatible with the pandemic period and while respecting the protection of the volunteer's personal data. The blood samples will be taken at 4 times: T0 (day of inclusion), 1 month, 3 months and 6 months' post-inclusion. Each blood sample consists of a collection of 5 mL of blood in a dry tube. The serum samples will be extracted and collected prospectively from the blood samples. A questionnaire will be completed by the inclusion volunteer (T0) in the study then 1, 3 and 6 months' post-inclusion.

NCT04369066 Volunteers From the Institute Curie Staff Who Are Not Showing Active SARS-CoV-2 Infection Diagnostic Test: Blood samples (collection of 5 mL of blood in a dry tube)

Primary Outcomes

Description: Detection of antibodies against the SARS-CoV-2 virus with serological tests

Measure: Antibodies against the SARS-CoV-2 virus in serum at inclusion

Time: 1 day

Description: Detection of antibodies against the SARS-CoV-2 virus with serological tests

Measure: Antibodies against the SARS-CoV-2 virus in serum at 1 month

Time: 1 month

Description: Detection of antibodies against the SARS-CoV-2 virus with serological tests

Measure: Antibodies against the SARS-CoV-2 virus in serum at 3 months

Time: 3 months

Description: Detection of antibodies against the SARS-CoV-2 virus with serological tests

Measure: Antibodies against the SARS-CoV-2 virus in serum at 6 months

Time: 6 months

Secondary Outcomes

Description: Comparative performance of anti-SARS-CoV-2 antibody detection techniques (sensitivity and specificity of serological tests)

Measure: Comparative performance of anti-SARS-CoV-2 antibody detection techniques

Time: 9 months

Description: Prevalence of immune subjects for SARS-CoV-2 in a well-defined active healthy population, working at the hospital or not, leading to variable exposure levels

Measure: Prevalence of immune subjects for SARS-CoV-2

Time: 3 months

Description: Nature and quantity of anti-SARS-CoV-2 antibodies: ImmunoglobulinM, ImmunoglobulinG and ImmunoglobulinA)

Measure: Nature and quantity of anti-SARS-CoV-2 antibodies

Time: 3 months

Description: The analysis of the evolution of serology results over time will be done by a mixed model taking into account the repeated framework of the data of a subject

Measure: Evolution of the different antibodies against the SARS-CoV-2 virus over time.

Time: 6 months


No related HPO nodes (Using clinical trials)