CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Cytokine profileWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (4)


Name (Synonyms) Correlation
drug651 Presatovir placebo Wiki 1.00
drug468 Loop mediated isothermal amplification COVID-19 Wiki 1.00
drug237 Covid-19 Antibody testing (IgG and IgM) Wiki 1.00
drug650 Presatovir Wiki 0.50

Correlated MeSH Terms (4)


Name (Synonyms) Correlation
D018357 Respiratory Syncytial Virus Infections NIH 0.50
D003141 Communicable Diseases NIH 0.12
D014777 Virus Diseases NIH 0.11
D007239 Infection NIH 0.08

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Rapid Diagnostics, Antibody Testing and Host Response in Children With COVID-19

Very little is known regarding the symptoms and signs of Covid-19 disease in children. In particular it is not know how many children are asymptomatic carriers of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and what the symptoms and signs of mild Covid-19 disease are. There is a need to understand the pattern of immunological (e.g. cytokine) response is in children who experience mild versus severer disease. There is also need to develop a rapid accurate point of care (POC) test for SARS-CoV-2 virus. Currently there is an opportunity to complete this research rapidly in Northern Ireland and because the province is 2-3 weeks behind mainland United Kingdom (UK) in the development of the COVID-19 epidemic and is ideally suited to this. In the midst of this rapidly evolving pandemic the RAPID-19 study is a pragmatic approach to addressing the above issues.

NCT04347408 COVID Diagnostic Test: Loop mediated isothermal amplification COVID-19 Diagnostic Test: Covid-19 Antibody testing (IgG and IgM) Diagnostic Test: Cytokine profile

Primary Outcomes

Measure: SARS-Cov2 positive molecular testing of throat/nasal swabs

Time: 6 months

Measure: Immunoglobulins (G and M) to SARS-Cov2 in plasma

Time: 6 months

Measure: Blood cytokine levels

Time: 6 months


No related HPO nodes (Using clinical trials)