Covid 19 Research using Clinical Trials (Home Page)
Cytokine profileWiki
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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (4)
Correlated MeSH Terms (4)
Correlated HPO Terms (0)
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There is one clinical trial.
Clinical Trials
Very little is known regarding the symptoms and signs of Covid-19 disease in children. In
particular it is not know how many children are asymptomatic carriers of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and what the symptoms and signs of mild
Covid-19 disease are. There is a need to understand the pattern of immunological (e.g.
cytokine) response is in children who experience mild versus severer disease. There is also
need to develop a rapid accurate point of care (POC) test for SARS-CoV-2 virus. Currently
there is an opportunity to complete this research rapidly in Northern Ireland and because the
province is 2-3 weeks behind mainland United Kingdom (UK) in the development of the COVID-19
epidemic and is ideally suited to this.
In the midst of this rapidly evolving pandemic the RAPID-19 study is a pragmatic approach to
addressing the above issues.
NCT04347408 COVID Diagnostic Test: Loop mediated isothermal amplification COVID-19 Diagnostic Test: Covid-19 Antibody testing (IgG and IgM) Diagnostic Test: Cytokine profile
Primary Outcomes
Measure: SARS-Cov2 positive molecular testing of throat/nasal swabs
Time: 6 months
Measure: Immunoglobulins (G and M) to SARS-Cov2 in plasma
Time: 6 months
Measure: Blood cytokine levels
Time: 6 months
No related HPO nodes (Using clinical trials)