CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


Equipment with smartwatch throughout hospital stay on the general wardWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug974 lopinavir/ritonavir tablets or Arbidol or chloroquine phosphate Wiki 1.00
drug177 Carrimycin Wiki 1.00
drug929 basic treatment Wiki 0.71

Correlated MeSH Terms (3)


Name (Synonyms) Correlation
D003141 Communicable Diseases NIH 0.12
D007239 Infection NIH 0.08
D018352 Coronavirus Infections NIH 0.06

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Wearable-based COVID-19 Markers for Prediction of Clinical Trajectories. The WAVE Study.

The aim is to develop a wearable-based ICU (intensive care unit) prediction algorithm for inpatients contracted with SARS-CoV-2. Inpatients with suspicion of COVID-19 or with confirmed SARS-CoV-2 infection will be included. The participants will be equipped with a smartwatch, which gathers physiological data throughout hospitalisation.

NCT04357834 COVID COVID 19 SARS-CoV 2 Other: Equipment with smartwatch throughout hospital stay on the general ward

Primary Outcomes

Description: Accuracy of the WAVE-model will be assessed using physiological data recorded by the smartwatch (Garmin vivoactive 4) during hospitalization complemented by demographic and health-related patient-information and will be analysed using applied machine learning technology for ICU prediction.

Measure: Diagnostic accuracy of smartwatch data in predicting ICU requirement in COVID-19 contracted inpatients quantified as the area under the receiver operator characteristics curve (AUC ROC > 0.85).

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Secondary Outcomes

Description: Accuracy of the model will be assessed using physiological data routinely recorded during hospitalization and will be analysed using applied machine learning technology for ICU prediction.

Measure: Diagnostic accuracy of routine physiological data in predicting ICU requirement in COVID-19 contracted in-patients quantified as the area under the receiver operator characteristics curve (AUC ROC > 0.85).

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Accuracy of the model will be assessed using data on comorbidities, medication treatment during hospitalization and physiological data and will be analysed using casual machine-learning approaches

Measure: Diagnostic accuracy of predicting hospital discharge without ICU admission in COVID-19 contracted in-patients quantified as area under the receiver operator characteristics curve

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Heart rate will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors.

Measure: Change of heart rate from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Heart rate variability will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)

Measure: Change of heart rate variability from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Skin temperature will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)

Measure: Change of skin temperature from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Blood oxygen saturation will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors

Measure: Change of blood oxygen saturation from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Respiration rate will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors

Measure: Change of respiration rate from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Physical activity will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)

Measure: Change of physical activity from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Stress level will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)

Measure: Change of stress level from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Sleep will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)

Measure: Change of sleep pattern from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Steps per day will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S)

Measure: Change of steps per day from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Systolic blood pressure will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors

Measure: Change of systolic blood pressure from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Diastolic blood pressure will be recorded throughout the hospitalization using a smartwatch (Garmin vivoactive 4S) and using routine medical monitors

Measure: Change of diastolic blood pressure from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Body temperature will be recorded throughout the hospitalization using a routine medical thermometer

Measure: Change of body temperature from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Oxygen partial pressure (pO2) will be routinely assessed during the hospitalization in arterial or venous blood gas analyses

Measure: Change of oxygen partial pressure (pO2) from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: CO2 partial pressure (pCO2) will be routinely assessed during the hospitalization in arterial or venous blood gas analyses

Measure: Change of CO2 partial pressure (pCO2) from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Blood pH will be routinely assessed during the hospitalization in arterial or venous blood gas analyses

Measure: Change of blood pH from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Bicarbonate will be routinely assessed during the hospitalization in arterial or venous blood gas analyses

Measure: Change of bicarbonate from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Base excess will be routinely assessed during the hospitalization in arterial or venous blood gas analyses

Measure: Change of base excess from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)

Description: Oxygen flow rate will be routinely assessed during the hospitalization

Measure: Change of oxygen flow rate from baseline (hospitalization) to ICU admission

Time: until hospital discharge, transfer to ICU or palliative care is initiated (expected to be on average after 7-30 days)


No related HPO nodes (Using clinical trials)