Correlated Drug Terms (2)

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	Name (Synonyms)	Correlation
drug144	CD24Fc Wiki	1.00
drug616	Placebo Wiki	0.10

Correlated MeSH Terms (1)

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	Name (Synonyms)	Correlation
D018352	Coronavirus Infections NIH	0.06

Correlated HPO Terms (0)

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	Name (Synonyms)	Correlation

Primary Outcomes

Description: Compare the time course of body temperature (fever) between two groups over time.

Measure: Time course of body temperature (fever)

Time: 14 days

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Description: Compare viral load between two groups over time.

Measure: Viral load over time

Time: 14 days

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Secondary Outcomes

Description: PaO2/FiO2 ratio

Measure: P/F ratio over time

Time: 14 days

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Description: SOFA, including assessment of respiratory, blood, liver, circulatory, nerve, kidney, from 0 to 4 scores in each systems, the higher scores mean a worse outcome.

Measure: Sequential organ failure assessment score(SOFA score) over time

Time: 14 days

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Measure: Pulmonary Severity Index (PSI)

Time: 14 days

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Description: Based on radiologist's assessment of inflammatory exudative disease, category as follows: significant improvement, partial improvement, no improvement, increase of partial exudation, significant increase in exudation, unable to judge.

Measure: Image examination of chest over time

Time: 14 days

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Measure: Proportion of subjects who progressed to critical illness or death

Time: 14 days

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Measure: Time from first dose to conversion to normal or mild pneumonia

Time: 14 days

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Measure: T-lymphocyte counts over time

Time: 14 days

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Measure: C-reactive protein levels over time

Time: 14 days

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Measure: Angiotensin II (Ang II) changes over time

Time: 14 days

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Measure: Angiotensin 1-7 (Ang 1-7) changes over time

Time: 14 days

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Measure: Angiotensin 1-5 (Ang 1-5) changes over time

Time: 14 days

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Measure: Renin changes over time

Time: 14 days

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Measure: Aldosterone changes over time

Time: 14 days

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Measure: Angiotensin-converting enzyme (ACE) changes over time

Time: 14 days

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Measure: Angiotensin-converting enzyme 2 (ACE2) changes over time

Time: 14 days

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Measure: Interleukin 6 (IL-6) changes over time

Time: 14 days

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Measure: Interleukin 8 (IL-8) changes over time

Time: 14 days

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Measure: Soluble tumor necrosis factor receptor type II (sTNFrII) changes over time

Time: 14 days

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Measure: Plasminogen activator inhibitor type-1 (PAI-1) changes over time

Time: 14 days

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Measure: Von willebrand factor (vWF) changes over time

Time: 14 days

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Measure: Tumor necrosis factor-α (TNF-α) changes over time

Time: 14 days

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Measure: Soluble receptor for advanced glycation end products (sRAGE) changes over time

Time: 14 days

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Measure: Surfactant protein-D (SP-D) changes over time

Time: 14 days

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Measure: Angiopoietin-2 changes over time

Time: 14 days

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Measure: Frequency of adverse events and severe adverse events

Time: 14 days

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