CovidResearchTrials by Shray Alag

CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)

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Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


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Name (Synonyms) Correlation

Correlated MeSH Terms (1)

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D018352 Coronavirus Infections NIH 0.06

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Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials

1 Renin Angiotensin System - CoronaVirus

The aim of the study is to demonstrate overactivation of Renin Angiotensine System (RAS) in positives COVID-19 patient, especially in those with the most serious clinical forms where the mortality of patients in intensive care is on average 50%. We are expecting two groups: a group of 25 positive COVID 19 patients in intensive care and a group of 25 positive COVID 19 hospitalized patients in conventional hospitalisation. We will measure RAS, serum potassium and collect data on the treatment of these patients (especially antihypertensive therapy) one week apart (at the patient'entry into hospital and 7 days later). This is a preliminary study that could possibly allow the start of a therapeutic trial in order to test the effectiveness of RAS blocker treatments in this condition.

NCT04337008 COVID 19 Other: blood draw
MeSH:Coronavirus Infections

Primary Outcomes

Description: demonstrate overactivity of RAS in patients hospitalised in intensive car secondary to COVID-19 compared to control patients (COVID -19 hospitalised patients without complications ).

Measure: overactivity of the renin / aldosterone system

Time: 7 days

No related HPO nodes (Using clinical trials)