Covid 19 Research using Clinical Trials (Home Page)
Pulmonary Physiotherapy TechniquesWiki
Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation
Correlated Drug Terms (0)
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Correlated HPO Terms (0)
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There is one clinical trial.
Clinical Trials
1 Efficacy of Pulmonary Physiotherapy on Hospitalized Patients With Novel Coronavirus 2019 Pneumonia
The aim of this study is to evaluate the efficacy of pulmonary physiotherapy on respiratory functions in hospitalized patients with Novel Coronavirus 2019 pneumonia. Patients will be randomized into 1) intervention group: receiving pulmonary physiotherapy technique to improve pulmonary function and walking training or 2) control group: Usual medical care. Patients in both groups will receive therapeutic incentive spirometer. Various outcome measurements of pulmonary functions will be evaluated before and after of interventions. Mortality rate, hospitalization duration and re-admission will be followed until one month after end of intervention. Also, patient's quality of life will be measured after one month.
NCT04357340 Covid-19 Pneumonia SARS Pneumonia Other: Pulmonary Physiotherapy Techniques MeSH:Pneumonia
HPO:Pneumonia
Primary Outcomes
Description: Partial pressure of oxygen in mixed venous blood.
Measure: Mixed venous O2 pressure (PVO2) Time: Baseline
Description: Partial pressure of oxygen in mixed venous blood.
Measure: Mixed venous O2 pressure (PVO2) Time: Day 3
Description: Partial pressure of carbon dioxide in mixed venous blood.
Measure: Mixed venous CO2 pressure (PVCO2) Time: Baseline
Description: Partial pressure of carbon dioxide in mixed venous blood.
Measure: Mixed venous CO2 pressure (PVCO2) Time: Day 3
Description: Measure of the venous blood acidity or alkalinity
Measure: PH Time: Baseline
Description: Measure of the venous blood acidity or alkalinity
Measure: PH Time: Day 3
Description: The amount of bicarbonate ion in the venous blood
Measure: HCO3 Time: Baseline
Description: The amount of bicarbonate ion in the venous blood
Measure: HCO3 Time: Day 3
Description: The amount of oxygen-saturated hemoglobin relative to total hemoglobin (unsaturated + saturated) in the venous blood
Measure: Oxygen saturation (O2 Sat) from VBG Time: Baseline
Description: The amount of oxygen-saturated hemoglobin relative to total hemoglobin (unsaturated + saturated) in the venous blood
Measure: Oxygen saturation (O2 Sat) from VBG Time: Day 3
Description: The distance a patient can walk during six minute
Measure: Six minute walk test Time: Baseline
Description: The distance a patient can walk during six minute
Measure: Six minute walk test Time: Day 3
Measure: O2 Sat after one minute walking Time: Baseline
Measure: O2 Sat after one minute walking Time: Day 3
Measure: O2 Sat after two minutes use of Partial Rebreather Time: Baseline
Measure: O2 Sat after two minutes use of Partial Rebreather Time: Day 3
Measure: O2 Sat after two minutes free air breathing Time: Baseline
Measure: O2 Sat after two minutes free air breathing Time: Day 3
Measure: O2 sat/ Fio2 Time: Baseline
Measure: O2 sat/ Fio2 Time: Day 3
Description: The amount of shortness of breath using Visual Analogue Scale (VAS). The minimum score is 0 and maximum is 10. The 0 score means no breathlessness and the 10 score is the maximum breathlessness.
Measure: breathlessness Time: Baseline
Description: The amount of shortness of breath using Visual Analogue Scale (VAS). The minimum score is 0 and maximum is 10. The 0 score means no breathlessness and the 10 score is the maximum breathlessness.
Measure: breathlessness Time: Day 3
Secondary Outcomes
Description: The number of dead subjects compared to total patients
Measure: Mortality rate Time: until one month
Description: Patients' hospitalization after discharge due to any reason
Measure: Number of participants with Rehospitalization Time: until one moth
Description: Using Short-form 36 questionnaire. The minimum score is 0 and the maximum score is 100. Higher scores mean patient's better quality of life.
Measure: The Health-Related Quality of Life (HRQOL) Time: One month after end of intervention
Related HPO nodes (Using clinical trials)
HP:0002090: Pneumonia
Genes 208
TIMM8A DNAH9 GAS8 DNAH11 TNFRSF11A TBC1D24 SPAG1 MS4A1 GAS2L2 CCDC151 NIPBL BTK LIG4 NFKB2 TCIRG1 IGLL1 RNF168 STAT3 TAF1 RSPH4A CFTR NME8 DNAAF4 LEP CCDC65 NADK2 CD55 COL11A2 NHLRC1 PEPD CFAP300 LTBP3 WAS DNAI1 TBCD IL2RG GFI1 NBN RSPH1 CCDC39 PMM2 ICOS TNFSF12 IFNGR1 CARD11 SFTPC DNAL1 OFD1 ZMYND10 IL21R FMO3 SLC35A1 PLOD1 ORC6 RAG2 CACNA1C GAS8 RYR1 CFAP298 GNPTAB TNFRSF13B KDM6A PANK2 RANBP2 CYBA USB1 UBB DOCK8 ADA DNAAF2 KMT2D SAMD9 MUC5B IL7R DNAAF1 ICOS RAG2 CARD11 PTPRC ALMS1 NOTCH3 NSMCE3 DNAI1 TNFRSF13C GRHL3 EGFR IL2RG DNAAF6 PNP DNAH5 SETBP1 CR2 CD3E ADA MASP2 SFTPA2 ACTA1 RAC1 TTC25 FCGR2A ZAP70 SPEF2 IGHM DNAAF5 NBN CD247 DDR2 CD19 ACADVL KIAA0586 TK2 BLNK ARMC4 SGCG RAG1 CXCR4 NCF1 SRP54 FOXP3 IRF8 CFAP221 RNU4ATAC KCNJ6 LRBA CD3D P4HTM SELENON CCDC114 TNFRSF13B PLG DCLRE1C SLC25A24 DCLRE1C ICOS IL7R FOXJ1 JAK3 IL2RG CASP8 RAG1 OSTM1 CFAP410 CCNO NCF2 UNC119 TNFRSF13C JAK3 RNF125 STK36 POLA1 CD19 CR2 DNAH1 RSPH3 RSPH9 CYBB DRC1 DCLRE1C CCDC103 DNAAF3 LRRC56 PIGN LRRC6 SP110 PRKCD ACP5 CCDC40 SLC35C1 BTK MTHFD1 PGM3 RAG1 TERT CHD7 CFB TGFB1 RNU4ATAC SMARCD2 NKX2-1 OFD1 ZBTB24 BTK DNAI2 WDR19 ZAP70 CD79B CD81 COL11A2 NFIX RAG2 ELANE AFF4 NFKB1 IL2RG TNFRSF13C TNFSF12 CCDC114 ADA GBA DNAJB13 RPGR CSPP1 RMRP EPM2A DNMT3B NFKB2 MCIDAS HYDIN SNP 0
Primary Outcomes
Description: Partial pressure of oxygen in mixed venous blood.
Measure: Mixed venous O2 pressure (PVO2) Time: BaselineDescription: Partial pressure of oxygen in mixed venous blood.
Measure: Mixed venous O2 pressure (PVO2) Time: Day 3Description: Partial pressure of carbon dioxide in mixed venous blood.
Measure: Mixed venous CO2 pressure (PVCO2) Time: BaselineDescription: Partial pressure of carbon dioxide in mixed venous blood.
Measure: Mixed venous CO2 pressure (PVCO2) Time: Day 3Description: Measure of the venous blood acidity or alkalinity
Measure: PH Time: BaselineDescription: Measure of the venous blood acidity or alkalinity
Measure: PH Time: Day 3Description: The amount of bicarbonate ion in the venous blood
Measure: HCO3 Time: BaselineDescription: The amount of bicarbonate ion in the venous blood
Measure: HCO3 Time: Day 3Description: The amount of oxygen-saturated hemoglobin relative to total hemoglobin (unsaturated + saturated) in the venous blood
Measure: Oxygen saturation (O2 Sat) from VBG Time: BaselineDescription: The amount of oxygen-saturated hemoglobin relative to total hemoglobin (unsaturated + saturated) in the venous blood
Measure: Oxygen saturation (O2 Sat) from VBG Time: Day 3Description: The distance a patient can walk during six minute
Measure: Six minute walk test Time: BaselineDescription: The distance a patient can walk during six minute
Measure: Six minute walk test Time: Day 3Measure: O2 Sat after one minute walking Time: Baseline
Measure: O2 Sat after one minute walking Time: Day 3
Measure: O2 Sat after two minutes use of Partial Rebreather Time: Baseline
Measure: O2 Sat after two minutes use of Partial Rebreather Time: Day 3
Measure: O2 Sat after two minutes free air breathing Time: Baseline
Measure: O2 Sat after two minutes free air breathing Time: Day 3
Measure: O2 sat/ Fio2 Time: Baseline
Measure: O2 sat/ Fio2 Time: Day 3
Description: The amount of shortness of breath using Visual Analogue Scale (VAS). The minimum score is 0 and maximum is 10. The 0 score means no breathlessness and the 10 score is the maximum breathlessness.
Measure: breathlessness Time: BaselineDescription: The amount of shortness of breath using Visual Analogue Scale (VAS). The minimum score is 0 and maximum is 10. The 0 score means no breathlessness and the 10 score is the maximum breathlessness.
Measure: breathlessness Time: Day 3Secondary Outcomes
Description: The number of dead subjects compared to total patients
Measure: Mortality rate Time: until one monthDescription: Patients' hospitalization after discharge due to any reason
Measure: Number of participants with Rehospitalization Time: until one mothDescription: Using Short-form 36 questionnaire. The minimum score is 0 and the maximum score is 100. Higher scores mean patient's better quality of life.
Measure: The Health-Related Quality of Life (HRQOL) Time: One month after end of intervention