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Self-prone position recommendationWiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug742 Serology Wiki 1.00
drug885 Usual care Wiki 1.00
drug740 Sequencing Wiki 1.00

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D018352 Coronavirus Infections NIH 0.06

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 COVID-19 smArtphone-based Trial of Non-ICU Admission Prone Positioning

Prone positioning is a well studied and validated treatment for severe acute respiratory distress syndrome (ARDS), however there are no randomized studies on the use of prone positioning in the non-intubated patient. The purpose of this trial is to investigate the use of prone positioning in SARS-CoV-2 infected patients who are not intubated. It is unknown if this intervention would be helpful in preventing further respiratory deterioration in terms of increasing supplemental oxygen requirements, endotracheal intubation, and ICU admission. The CATNAP Study is a pragmatic adaptive randomized controlled unblinded trial. CATNAP compares a smartphone tool that recommends non-ICU patients with COVID-19 or who are under evaluation for COVID-19 to lie in a prone position (i.e, with their stomach and chest facing down) to usual care.

NCT04344587 COVID-19 Other: Self-prone position recommendation Other: Usual care

Primary Outcomes

Description: Change in respiratory status will be defined as:1) admission to the ICU and/or a 2) an increase in supplemental oxygen delivery (defined as an increase in oxygen delivery rate of ≥2 liter per minute compared to the oxygen delivery rate at the time of intervention or usual care text message that is sustained for ≥12 or more hours OR the switch to an oxygen delivery method that increases the level of supplemental oxygen.

Measure: Change in respiratory status

Time: up to 30 days

Secondary Outcomes

Description: Length of time in the prone position will be assessed from the smartphone survey and measured in categories of no time, up to 6 hours, 6 hours to 11 hours, 12 hours or more.

Measure: Length of time participant spends in the prone position

Time: up to 30 days

Description: Length of time in the supine/lying on back position will be assessed from the smartphone survey and measured in categories of no time, up to 6 hours, 6 hours to 11 hours, 12 hours or more.

Measure: Length of time participant spends in the supine position

Time: up to 30 days

Description: Length of time lying on side will be assessed from the smartphone survey and measured in categories of no time, up to 6 hours, 6 hours to 11 hours, 12 hours or more.

Measure: Length of time participant spends lying on side

Time: up to 30 days

Description: Length of time sitting up will be assessed from the smartphone survey and measured in categories of no time, up to 6 hours, 6 hours to 11 hours, 12 hours or more.

Measure: Length of time participant spends sitting up

Time: up to 30 days

Description: Length of time standing or walking will be assessed from the smartphone survey and measured in categories of no time, up to 6 hours, 6 hours to 11 hours, 12 hours or more.

Measure: Length of time participant spends standing or walking

Time: up to 30 days

Description: Dyspnea will be assessed by the modified Borg Dyspnea Score (10-point ordinal scale) from 1= nothing at all to 10= maximal. Higher scores indicate more dyspnea.

Measure: Dyspnea or difficult/labored breathing

Time: up to 30 days

Description: Discomfort with proning (4-point ordinal scale: very comfortable, somewhat comfortable, somewhat uncomfortable, very uncomfortable)

Measure: Discomfort with proning

Time: up to 30 days

Description: Total number of days hospitalized will be abstracted from the electronic medical record.

Measure: Length of hospital stay

Time: up to 30 days

Description: Invasive mechanical ventilation will be abstracted from the electronic medical record.

Measure: Invasive mechanical ventilation

Time: up to 30 days

Description: Loss of IV access as a consequence of turning in bed will be reported by participant using monitoring surveys

Measure: Loss of IV access as a consequence of turning in bed

Time: up to 30 days

Description: ARDS diagnosis will be abstracted from the electronic medical record

Measure: Acute respiratory distress syndrome (ARDS) diagnosis

Time: up to 30 days

Description: Hospital mortality will be abstracted from the electronic medical record

Measure: Hospital mortality

Time: up to 30 days


No related HPO nodes (Using clinical trials)