CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


NestCell®Wiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (0)


Name (Synonyms) Correlation

Correlated MeSH Terms (1)


Name (Synonyms) Correlation
D011014 Pneumonia NIH 0.08

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Exploratory Clinical Study to Assess the Efficacy of NestCell® Mesenchymal Stem Cell to Treat Patients With Severe COVID-19 Pneumonia

This is an exploratory study to assess the efficacy of NestCell® (mesenchymal stem cell) to treat severe COVID-19 pneumonia.

NCT04315987 COVID-19 Pneumonia Biological: NestCell®
MeSH:Pneumonia
HPO:Pneumonia

Primary Outcomes

Description: Ordinal scale (WHO ordinal scale that measures illness severity over time)

Measure: Change in Clinical Condition

Time: 10 days

Secondary Outcomes

Description: Evaluation of Pneumonia change

Measure: Rate of mortality within 10-days

Time: 10 days

Description: Evaluation of Pneumonia change

Measure: Change of Clinical symptoms - respiratory rate

Time: 10 days

Description: oxygen saturation

Measure: Hypoxia

Time: 10 days

Description: oxygen saturation

Measure: PaO2 / FiO2 ratio

Time: 10 days

Description: Marker of Immunological function

Measure: CD4+ and CD8+ T cell count

Time: Days 1, 2, 4, 6 and 8.

Description: PaO2 / FiO2 ratio

Measure: Changes of blood oxygen

Time: 10 days

Description: Number of participants with treatment-related adverse events

Measure: Side effects in the treatment group

Time: 10 days

Description: Complete blood count, ALT, AST, GGT, CK, CKmB and creatinine

Measure: Complete blood count, cardiac, hepatic and renal profiles;

Time: Days 1, 2, 4, 6 and 8.


Related HPO nodes (Using clinical trials)