CovidResearchTrials by Shray Alag


CovidResearchTrials Covid 19 Research using Clinical Trials (Home Page)


WHO recommendations (waiting condition)Wiki

Developed by Shray Alag
Clinical Trial MeSH HPO Drug Gene SNP Protein Mutation


Correlated Drug Terms (3)


Name (Synonyms) Correlation
drug328 Guided online support program Wiki 1.00
drug9 1: Usual practice Wiki 1.00
drug15 2: Usual practice + SYMBICORT RAPIHALER Wiki 1.00

Correlated MeSH Terms (4)


Name (Synonyms) Correlation
D012120 Respiration Disorders NIH 0.50
D012140 Respiratory Tract Diseases NIH 0.38
D003141 Communicable Diseases NIH 0.12
D007239 Infection NIH 0.08

Correlated HPO Terms (0)


Name (Synonyms) Correlation

There is one clinical trial.

Clinical Trials


1 Online Support for Psychosocial Stress in the Context of the COVID-19 Pandemic

The COVID-19 pandemic leads to a greatly increased risk of substantial psychological stress worldwide. We intend to evaluate an online support program aiming at reducing stress in the context of the COVID-19 pandemic. The program consists of twelve modules that participants undergo, covering a broad range of topics related to stress in the context of the COVID-19 pandemic. It has been developed together with and is provided by Selfapy GmbH, Berlin. The aim of this randomised clinical trial with observational components is to estimate the effects of the intervention as a whole, as well as individual modules and selected chapters. Further, follow-up assessments as well as information on risks and the long-term course of COVID pandemic-related stress may help to elucidate COVID-19 pandemic stress across time and what we can do to prevent long-term negative consequences.

NCT04324190 COVID-19 Psychosocial Stress Mental Health Behavioral: Guided online support program Behavioral: WHO recommendations (waiting condition)

Primary Outcomes

Description: The SF-36 is a widely used patient-reported outcome assessment tool to measure health-related quality of life and has high acceptability. The SF-36 is a standardised questionnaire with good psychometric properties.

Measure: Change in Short-Form-36 (SF-36) Health Survey - Mental Health Component Summary score

Time: Change from T1 (baseline before online support - day 1) to T2 (T1 + 2 weeks) in arm 1, versus change from T0 (baseline before waiting) to T1 (baseline before online support) in arm 2

Secondary Outcomes

Description: mental health related quality of life

Measure: Short-Form-36 (SF-36) Health Survey - Mental Health Component Summary score

Time: T2 (T1+2 weeks) (arm 2 only), T3 (T1+4 weeks), T4 (T1+12 weeks), follow ups: T1+ 6 months, T1+12 months

Description: Assessing chronic stress (Petrowski et al., 2019)

Measure: Chronic stress items (9 items)

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T2 (T1+2 weeks), T3 (T1+4 weeks), T4 (T1+12 weeks), follow ups: T1+ 6 months, T1+12 months

Description: Assessing anxiety symptoms (Löwe et al., 2008)

Measure: Generalized Anxiety Disorder Scale (GAD-7)

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T2 (T1+2 weeks), T3 (T1+4 weeks), T4 (T1+12 weeks), follow ups: T1+ 6 months, T1+12 months

Description: Assessing depressive symptoms (Kroenke et al., 2001)

Measure: Patient Health Questionnaire (PHQ8)

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T2 (T1+2 weeks), T3 (T1+4 weeks), T4 (T1+12 weeks), follow ups: T1+ 6 months, T1+12 months

Description: Assessing depressive symptoms (Toussaint et al., 2019)

Measure: Somatic Symptom Disorder (SSD-12)

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T2 (T1+2 weeks), T3 (T1+4 weeks), T4 (T1+12 weeks), follow ups: T1+ 6 months, T1+12 months

Description: Assessing somatic symptoms (Gierk et al., 2015)

Measure: Somatic Symptom Scale (SSS-8)

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T2 (T1+2 weeks), T3 (T1+4 weeks), T4 (T1+12 weeks), follow ups: T1+ 6 months, T1+12 months

Description: competence expectations to deal with difficulties and obstacles in daily life (Beierlein et al., 2014)

Measure: Allgemeine Selbstwirksamkeit Kurzskala (ASKU)

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T2 (T1+2 weeks), T3 (T1+4 weeks), T4 (T1+12 weeks), follow ups: T1+ 6 months, T1+12 months

Description: stress, anxiety, depression, social support - single item assessments to be applied repeatedly along the online support intervention (Young, Ignaszewski, Fofonoff, Kaan; 2007), including stress of children and anticipation

Measure: Screening Tool for Psychological Distress (STOP-D) - selected items

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T1+2 weeks, T1+4 weeks, T1+12 weeks, follow ups: T1+ 6 months, T1+12 months; before & after each module of the online intervention

Other Outcomes

Description: Vigorous, moderate, and walking activity (minutes/day)

Measure: Physical activity

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T1+2 weeks, T1+4 weeks, T1+12 weeks, follow ups: T1+ 6 months, T1+12 months; before & after sports and physical activity module; at baseline: before COVID-19 pandemic

Description: Questions related to home-schooling related stress & learning

Measure: Home-schooling

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T1+2 weeks, T1+4 weeks, T1+12 weeks, follow ups: T1+ 6 months, T1+12 months; before & after sports and physical activity module; at baseline: before COVID-19 pandemic

Description: Questions related to COVID-19 and SARS-CoV-2 symptoms, disease, and testing, anxiety, stressors

Measure: Information related to COVID-19 and SARS-CoV-2

Time: baseline before waiting (T0, arm 2 only); baseline before online support (day 1, T1), T1+2 weeks, T1+4 weeks, T1+12 weeks, follow ups: T1+ 6 months, T1+12 months; before & after the sports and physical activity module of the online intervention

Description: Unintended effects of online support program

Measure: Unintended effects

Time: only after undergoing online support program: T1+2 weeks, T1+4 weeks, T1+12 weeks, follow ups: T1+ 6 months, T1+12 months


No related HPO nodes (Using clinical trials)